Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity

Biochemical transformation of calciprotein particles in uraemia

(2018) Edward R. Smith et al.   BONE

Patients with advanced chronic kidney disease and vascular calcification have a large hydrodynamic radius of secondary calciprotein particles

(2018) Wei Chen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Bone marrow lympho-myeloid malfunction in obesity requires precursor cell-autonomous TLR4

(2018) Ailing Liu et al.   Nature Communications

Identification and quantification of plasma calciprotein particles with distinct physical properties in patients with chronic kidney disease

(2018) Yutaka Miura et al.   Scientific Reports

Macrophage Recognition of Crystals and Nanoparticles

(2018) Masafumi Nakayama   Frontiers in Immunology

A novel fluorescent probe-based flow cytometric assay for mineral-containing nanoparticles in serum

(2017) Edward R. Smith et al.   Scientific Reports

Worsening calcification propensity precedes all-cause and cardiovascular mortality in haemodialyzed patients

(2017) Georg Lorenz et al.   Scientific Reports

In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice

(2016) Raymond Reif et al.   ARCHIVES OF TOXICOLOGY

Calcification of vascular smooth muscle cells is induced by secondary calciprotein particles and enhanced by tumor necrosis factor-α

(2016) Parisa Aghagolzadeh et al.   ATHEROSCLEROSIS

Blood Calcification Propensity, Cardiovascular Events, and Survival in Patients Receiving Hemodialysis in the EVOLVE Trial

(2016) Andreas Pasch et al.   Clinical Journal of the American Society of Nephrology

K+Efflux Agonists Induce NLRP3 Inflammasome Activation Independently of Ca2+Signaling

(2015) Michael A. Katsnelson et al.   JOURNAL OF IMMUNOLOGY

Calcification Propensity and Survival among Renal Transplant Recipients

(2015) C. A. Keyzer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Artefactual nanoparticle activation of the inflammasome platform: in vitro evidence with a nano-formed calcium phosphate

(2015) Laetitia Pele et al.   Nanomedicine

Serum Calcification Propensity Predicts All-Cause Mortality in Predialysis CKD

(2013) E. R. Smith et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism

(2013) Makoto Kuro-o   Nature Reviews Nephrology

Fetuin-A-Containing Calciprotein Particles Reduce Mineral Stress in the Macrophage

(2013) Edward R. Smith et al.   PLoS One

Bions: A Family of Biomimetic Mineralo-Organic Complexes Derived from Biological Fluids

(2013) Cheng-Yeu Wu et al.   PLoS One

The Role of Fetuin-A in Physiological and Pathological Mineralization

(2012) Laura Brylka et al.   CALCIFIED TISSUE INTERNATIONAL

Clearance of Fetuin-A–Containing Calciprotein Particles Is Mediated by Scavenger Receptor-A

(2012) Marietta Herrmann et al.   CIRCULATION RESEARCH

Dietary phosphate restriction ameliorates endothelial dysfunction in adenine-induced kidney disease rats

(2012) Tan Vu Van et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Nanoparticle-Based Test Measures Overall Propensity for Calcification in Serum

(2012) A. Pasch et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Effects of Phosphate Binders in Moderate CKD

(2012) G. A. Block et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

High phosphate directly affects endothelial function by downregulating annexin II

(2012) Giovana Seno Di Marco et al.   KIDNEY INTERNATIONAL

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Serum fetuin-A concentration and fetuin-A-containing calciprotein particles in patients with chronic inflammatory disease and renal failure

(2012) Edward R Smith et al.   NEPHROLOGY

Physicochemical and Biological Properties of Biomimetic Mineralo-Protein Nanoparticles Formed Spontaneously in Biological Fluids

(2012) Hsin-Hsin Peng et al.   Small

Comparison of Calcium Acetate and Sevelamer on Vascular Function and Fibroblast Growth Factor 23 in CKD Patients: A Randomized Clinical Trial

(2011) Mahmut Ilker Yilmaz et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1  Secretion through the NLRP3 Inflammasome In Vitro

(2011) B. Pazar et al.   JOURNAL OF IMMUNOLOGY

NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite-associated arthropathy

(2011) C. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation and stability kinetics of calcium phosphate–fetuin-A colloidal particles probed by time-resolved dynamic light scattering

(2011) Johanna Wald et al.   Soft Matter

Fetuin-A Is a Mineral Carrier Protein: Small Angle Neutron Scattering Provides New Insight on Fetuin-A Controlled Calcification Inhibition

(2010) Alexander Heiss et al.   BIOPHYSICAL JOURNAL

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

(2010) Fabio Martinon et al.   NATURE IMMUNOLOGY

The Case ∣ Milky ascites is not always chylous

(2009) K.M. Olde Loohuis et al.   KIDNEY INTERNATIONAL

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Hierarchical Role of Fetuin-A and Acidic Serum Proteins in the Formation and Stabilization of Calcium Phosphate Particles

(2008) Alexander Heiss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY