Are “Resting” Microglia More “M2”?

CNS myelin induces regulatory functions of DC-SIGN–expressing, antigen-presenting cells via cognate interaction with MOG

(2014) J.J. García-Vallejo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

M1 and M2 Macrophages: The Chicken and the Egg of Immunity

(2014) Charles D. Mills et al.   Journal of Innate Immunity

Phagosome maturation in polarized macrophages

(2014) Johnathan Canton   JOURNAL OF LEUKOCYTE BIOLOGY

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators

(2013) Hyeon-Sook Suh et al.   Journal of Neuroinflammation

Layer V cortical neurons require microglial support for survival during postnatal development

(2013) Masaki Ueno et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Aging enhances classical activation but mitigates alternative activation in the central nervous system

(2013) Daniel C. Lee et al.   NEUROBIOLOGY OF AGING

Microglia: A new frontier for synaptic plasticity, learning and memory, and neurodegenerative disease research

(2013) Gary P. Morris et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Factors regulating microglia activation

(2013) Katrin Kierdorf et al.   Frontiers in Cellular Neuroscience

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Neuroinflammation and Synaptic Loss

(2012) Jagadeesh S. Rao et al.   NEUROCHEMICAL RESEARCH

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Lipopolysaccharide-induced interleukin (IL)-4 receptor-α expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice

(2011) Ashley M. Fenn et al.   BRAIN BEHAVIOR AND IMMUNITY

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Alternatively activated myeloid (M2) cells enhance cognitive function in immune compromised mice

(2010) Noel C. Derecki et al.   BRAIN BEHAVIOR AND IMMUNITY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Regulation of learning and memory by meningeal immunity: a key role for IL-4

(2010) Noël C. Derecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS

(2008) Alexander H. de Haas et al.   GLIA

Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: Underlying mechanisms

(2008) J.L. Teeling et al.   NEUROSCIENCE

Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain

(2007) David J. Loane et al.   NEUROBIOLOGY OF AGING