“Small Talk” in the Innate Immune System via RNA-Containing Extracellular Vesicles

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes

(2014) Ugur Gezer et al.   CELL BIOLOGY INTERNATIONAL

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Dendritic Cell-Derived Exosomes as Immunotherapies in the Fight against Cancer

(2014) J. M. Pitt et al.   JOURNAL OF IMMUNOLOGY

Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles

(2014) Ethel Bayer-Santos et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

(2014) Kaushik Choudhuri et al.   NATURE

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

(2014) L. Vojtech et al.   NUCLEIC ACIDS RESEARCH

Exosomes: An emerging factor in stress-induced immunomodulation

(2014) Lida A. Beninson et al.   SEMINARS IN IMMUNOLOGY

Gene Expression Changes Induced byTrypanosoma cruziShed Microvesicles in Mammalian Host Cells: Relevance of tRNA-Derived Halves

(2014) Maria R. Garcia-Silva et al.   Biomed Research International

Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer

(2014) Kenji Takahashi et al.   FEBS Open Bio

tRNAs as regulators of biological processes

(2014) Medha Raina et al.   Frontiers in Genetics

CD169 mediates the capture of exosomes in spleen and lymph node

(2013) S. C. Saunderson et al.   BLOOD

Characterization of human plasma-derived exosomal RNAs by deep sequencing

(2013) Xiaoyi Huang et al.   BMC GENOMICS

Exosomes released in vitro from Epstein–Barr virus (EBV)-infected cells contain EBV-encoded latent phase mRNAs

(2013) Andrea Canitano et al.   CANCER LETTERS

Microvesicle-mediated Transfer of MicroRNA-150 from Monocytes to Endothelial Cells Promotes Angiogenesis

(2013) Jing Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Dendritic Cell-Derived Exosomes Need To Activate Both T and B Cells To Induce Antitumor Immunity

(2013) T. I. Naslund et al.   JOURNAL OF IMMUNOLOGY

MicroRNAs Transfer from Human Macrophages to Hepato-Carcinoma Cells and Inhibit Proliferation

(2013) A. Aucher et al.   JOURNAL OF IMMUNOLOGY

Exosome-Derived miRNAs and Cellular miRNAs Activate Innate Immunity

(2013) Anne Mobergslien et al.   Journal of Innate Immunity

miR-223: infection, inflammation and cancer

(2013) M. Haneklaus et al.   JOURNAL OF INTERNAL MEDICINE

Human Plasmacytoid Dendritic Cells Sense Lymphocytic Choriomeningitis Virus-Infected Cells In Vitro

(2013) S. F. Wieland et al.   JOURNAL OF VIROLOGY

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Extracellular vesicles shed by Trypanosoma cruzi are linked to small RNA pathways, life cycle regulation, and susceptibility to infection of mammalian cells

(2013) Maria R. Garcia-Silva et al.   PARASITOLOGY RESEARCH

Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells

(2013) Cheryl CY Li et al.   RNA Biology

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Microvesicles and intercellular communication in the context of parasitism

(2013) Natasha S. Barteneva et al.   Frontiers in Cellular and Infection Microbiology

Extracellular small RNAs: what, where, why?: Figure 1

(2012) Anna M. Hoy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Macrophage microvesicles induce macrophage differentiation and miR-223 transfer

(2012) N. Ismail et al.   BLOOD

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

(2012) Jasenka Guduric-Fuchs et al.   BMC GENOMICS

Short-Range Exosomal Transfer of Viral RNA from Infected Cells to Plasmacytoid Dendritic Cells Triggers Innate Immunity

(2012) Marlène Dreux et al.   Cell Host & Microbe

Immune Cell-derived Vesicles: Modulators and Mediators of Inflammation

(2012) Esther N.M. Nolte-‘t Hoen et al.   CURRENT PHARMACEUTICAL DESIGN

How the immune system talks to itself: the varied role of synapses

(2012) Jianming Xie et al.   IMMUNOLOGICAL REVIEWS

Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life

(2012) Brooke L. Deatherage et al.   INFECTION AND IMMUNITY

Toward tailored exosomes: The exosomal tetraspanin web contributes to target cell selection

(2012) Sanyukta Rana et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1  Production

(2012) M. Haneklaus et al.   JOURNAL OF IMMUNOLOGY

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

(2012) Esther N. M. Nolte-’t Hoen et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mast cell synapses and exosomes: membrane contacts for information exchange

(2012) Amanda Carroll-Portillo   Frontiers in Immunology

TLR4 signaling induces the release of microparticles by tumor cells that regulate inflammatory cytokine IL-6 of macrophages via microRNA let-7b

(2012) Dapeng Li et al.   OncoImmunology

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesicles

(2011) Arsen O Batagov et al.   BMC GENOMICS

Microvesicles and Viral Infection

(2011) D. G. Meckes et al.   JOURNAL OF VIROLOGY

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles

(2010) Adam Kulp et al.   Annual Review of Microbiology

Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease

(2010) Kevin C. Miranda et al.   KIDNEY INTERNATIONAL

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

Exosomal Hsp70 Induces a Pro-Inflammatory Response to Foreign Particles Including Mycobacteria

(2010) Paras K. Anand et al.   PLoS One

Exosomes Communicate Protective Messages during Oxidative Stress; Possible Role of Exosomal Shuttle RNA

(2010) Maria Eldh et al.   PLoS One

Functional delivery of viral miRNAs via exosomes

(2010) D. M. Pegtel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human tRNA-derived small RNAs in the global regulation of RNA silencing

(2010) D. Haussecker et al.   RNA

Extra-cellular release and blood diffusion of BART viral micro-RNAs produced by EBV-infected nasopharyngeal carcinoma cells

(2010) Claire Gourzones et al.   Virology Journal

The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs

(2009) Helena Persson et al.   NATURE CELL BIOLOGY

Silencing by small RNAs is linked to endosomal trafficking

(2009) Young Sik Lee et al.   NATURE CELL BIOLOGY

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY

MHC II in Dendritic Cells is Targeted to Lysosomes or T Cell-Induced Exosomes Via Distinct Multivesicular Body Pathways

(2009) Sonja I. Buschow et al.   TRAFFIC

Activated T cells recruit exosomes secreted by dendritic cells via LFA-1

(2008) E. N. M. Nolte-'t Hoen et al.   BLOOD

B lymphocytes and macrophages release cell membrane deposited C3-fragments on exosomes with T cell response-enhancing capacity☆

(2008) Krisztián Papp et al.   MOLECULAR IMMUNOLOGY

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE