Elucidation of Pathways Driving Asthma Pathogenesis: Development of a Systems-Level Analytic Strategy

Bayesian Inference of Multiple Gaussian Graphical Models

(2015) Christine Peterson et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Defective Respiratory Tract Immune Surveillance in Asthma

(2014) Patrick G. Holt et al.   CHEST

Erratum: Corrigendum: Unifying immunology with informatics and multiscale biology

(2014) Brian A Kidd et al.   NATURE IMMUNOLOGY

A longitudinal study of lung function from 1 month to 18 years of age

(2014) Steve Turner et al.   THORAX

Persistent Effects of Maternal Smoking during Pregnancy on Lung Function and Asthma in Adolescents

(2013) Elysia M. Hollams et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Impact of preterm birth and bronchopulmonary dysplasia on the developing lung: Long-term consequences for respiratory health

(2013) Megan O'Reilly et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Th17-mediated inflammation in asthma

(2013) Dawn C Newcomb et al.   CURRENT OPINION IN IMMUNOLOGY

Risk of childhood asthma following infant bronchiolitis during the respiratory syncytial virus season

(2013) Kristina M. James et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

(2013) Blanca E. Himes et al.   PLoS One

Bayesian Networks for Clinical Decision Support in Lung Cancer Care

(2013) M. Berkan Sesen et al.   PLoS One

A Network Inference Method for Large-Scale Unsupervised Identification of Novel Drug-Drug Interactions

(2013) Roger Guimerà et al.   PLoS Computational Biology

Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort

(2012) Ben D. Spycher et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Viral infections and atopy in asthma pathogenesis: new rationales for asthma prevention and treatment

(2012) Patrick G Holt et al.   NATURE MEDICINE

Childhood Overweight/Obesity and Asthma: Is There a Link? A Systematic Review of Recent Epidemiologic Evidence

(2012) Constantina Papoutsakis et al.   Journal of the Academy of Nutrition and Dietetics

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

(2012) Ke Hao et al.   PLoS Genetics

Cord blood Tregs with stable FOXP3 expression are influenced by prenatal environment and associated with atopic dermatitis at the age of one year

(2011) D. Hinz et al.   ALLERGY

Evidence for a Causal Relationship between Allergic Sensitization and Rhinovirus Wheezing in Early Life

(2011) Daniel J. Jackson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hospitalisation for bronchiolitis in infants is more common after elective caesarean delivery

(2011) Hannah C Moore et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Developmental regulation of Th17-cell capacity in human neonates

(2011) Allison Black et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Relationship between parental lung function and their children's lung function early in life

(2011) N. van Putte-Katier et al.   EUROPEAN RESPIRATORY JOURNAL

Relationship between past airway pathology and current lung function in preschool wheezers

(2011) S. Sonnappa et al.   EUROPEAN RESPIRATORY JOURNAL

Febrile respiratory illnesses in infancy and atopy are risk factors for persistent asthma and wheeze

(2011) M.M.H. Kusel et al.   EUROPEAN RESPIRATORY JOURNAL

Risk factors for bronchial hyperresponsiveness in teenagers differ with sex and atopic status

(2011) Rachel A. Collins et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The protective effect of farm milk consumption on childhood asthma and atopy: The GABRIELA study

(2011) Georg Loss et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effect of day care attendance on sensitization and atopic wheezing differs by Toll-like receptor 2 genotype in 2 population-based birth cohort studies

(2011) Adnan Custovic et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Gene-environment interaction for childhood asthma and exposure to farming in Central Europe

(2011) Markus J. Ege et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthma

(2011) Theresa W. Guilbert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

(2011) María Soler Artigas et al.   NATURE GENETICS

Gene-environment interactions in chronic inflammatory disease

(2011) Harald Renz et al.   NATURE IMMUNOLOGY

Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C

(2011) Yury A Bochkov et al.   NATURE MEDICINE

Effect of Bronchoconstriction on Airway Remodeling in Asthma

(2011) Christopher L. Grainge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised children

(2011) Belinda J Hales et al.   THORAX

Lung function, airway remodelling and inflammation in symptomatic infants: outcome at 3 years

(2011) K. Malmstrom et al.   THORAX

Genome-wide association studies and systems biology: together at last

(2011) Mika Ala-Korpela et al.   TRENDS IN GENETICS

T regulatory cells in childhood asthma

(2011) Deborah H. Strickland et al.   TRENDS IN IMMUNOLOGY

Beyond Atopy

(2010) Angela Simpson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Statistical inference of the time-varying structure of gene-regulation networks

(2010) Sophie Lèbre et al.   BMC Systems Biology

Th2-associated immunity to bacteria in teenagers and susceptibility to asthma

(2010) E. M. Hollams et al.   EUROPEAN RESPIRATORY JOURNAL

Association between human rhinovirus C and severity of acute asthma in children

(2010) J. Bizzintino et al.   EUROPEAN RESPIRATORY JOURNAL

Do early-life viral infections cause asthma?

(2010) Peter D. Sly et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study

(2010) Patrick G. Holt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Weekly monitoring of children with asthma for infections and illness during common cold seasons

(2010) Jaime P. Olenec et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Gene Expression Patterns of Th2 Inflammation and Intercellular Communication in Asthmatic Airways

(2010) D. F. Choy et al.   JOURNAL OF IMMUNOLOGY

Metabonomic, transcriptomic, and genomic variation of a population cohort

(2010) Michael Inouye et al.   Molecular Systems Biology

Decreased activation of inflammatory networks during acute asthma exacerbations is associated with chronic airflow obstruction

(2010) A Bosco et al.   Mucosal Immunology

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Disordered Microbial Communities in Asthmatic Airways

(2010) Markus Hilty et al.   PLoS One

Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life

(2010) N. Sigurs et al.   THORAX

An Immune Response Network Associated with Blood Lipid Levels

(2010) Michael Inouye et al.   PLoS Genetics

Establishment of the gut microbiota in Western infants

(2009) I Adlerberth et al.   ACTA PAEDIATRICA

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

(2009) Wendy C. Moore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells

(2009) Bianca Schaub et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing

(2009) John W. Upham et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Elucidation of asthma phenotypes in atopic teenagers through parallel immunophenotypic and clinical profiling

(2009) Elysia M. Hollams et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbeAcinetobacter lwoffiiF78

(2009) Melanie L. Conrad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Soothing signals: transplacental transmission of resistance to asthma and allergy: Figure 1.

(2009) Patrick G. Holt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults

(2009) T. R. Kollmann et al.   JOURNAL OF IMMUNOLOGY

Therapeutic manipulation of immune tolerance in allergic disease

(2009) Mübeccel Akdis et al.   NATURE REVIEWS DRUG DISCOVERY

The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study population

(2009) James E Gern et al.   BMC Pulmonary Medicine

Increased Airway Smooth Muscle Mass in Children with Asthma, Cystic Fibrosis, and Non-Cystic Fibrosis Bronchiectasis

(2008) Nicolas Regamey et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evidence of a Causal Role of Winter Virus Infection during Infancy in Early Childhood Asthma

(2008) Pingsheng Wu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interleukin-10/Interleukin-5 Responses at Birth Predict Risk for Respiratory Infections in Children with Atopic Family History

(2008) Guicheng Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Severe Exacerbations and Decline in Lung Function in Asthma

(2008) Paul M. O'Byrne et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Modulation of the epithelial inflammatory response to rhinovirus in an atopic environment

(2008) M. Xatzipsalti et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Induction, function and regulation of IL-17-producing T cells

(2008) Kingston H. G. Mills   EUROPEAN JOURNAL OF IMMUNOLOGY

Living on a Farm: Impact on Asthma Induction and Clinical Course

(2008) Erika von Mutius et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Impairment of T-regulatory cells in cord blood of atopic mothers

(2008) Bianca Schaub et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The cytokine network in asthma and chronic obstructive pulmonary disease

(2008) Peter J. Barnes   JOURNAL OF CLINICAL INVESTIGATION

Wheezing and bronchial hyper-responsiveness in early childhood as predictors of newly diagnosed asthma in early adulthood: a longitudinal birth-cohort study

(2008) Debra A Stern et al.   LANCET

Early identification of atopy in the prediction of persistent asthma in children

(2008) Peter D Sly et al.   LANCET

Is caesarean delivery associated with sensitization to food allergens and IgE-mediated food allergy: A systematic review

(2008) Jennifer Koplin et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Lower levels of plasmacytoid dendritic cells in peripheral blood are associated with a diagnosis of asthma 6 yr after severe respiratory syncytial virus bronchiolitis

(2008) Eli Silver et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

USING DIRECTED INFORMATION TO BUILD BIOLOGICALLY RELEVANT INFLUENCE NETWORKS

(2008) ARVIND RAO et al.   Journal of Bioinformatics and Computational Biology

A meta-analysis of the association between Caesarean section and childhood asthma

(2007) S. Thavagnanam et al.   CLINICAL AND EXPERIMENTAL ALLERGY