Article
Nutrition & Dietetics
Manfred J. Mueller, Steven B. Heymsfield, Anja Bosy-Westphal
Summary: This study evaluated the impact of changes in fat-free mass (FFM) composition on adaptive thermogenesis (AT), finding that changes in FFM composition had a significant effect on weight loss and weight gain. Adjusting for changes in anatomical and molecular composition reduced AT after caloric restriction (CR) and increased AT after overfeeding (OF), but the overall adjusted AT may not be enough to prevent weight loss or resist weight gain.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Anastasios Koutsoumparis, Luisa M. Welp, Alexander Wulf, Henning Urlaub, David Meierhofer, Stefan Boerno, Bernd Timmermann, Inka Busack, Henrik Bringmann
Summary: This study reveals the role of sleep-active neurons in promoting protective gene expression during sleep. Disturbing sleep leads to increased depolarization of sleep-active neurons and further enhances protective gene expression. The findings suggest that sleep deprivation induces a cellular stress response mediated by overactivation of sleep-active neurons.
Article
Biochemistry & Molecular Biology
Zan Song, Lin Liu, Yanyi Xu, Ruofan Cao, Xianyong Lan, Chuanying Pan, Shengxiang Zhang, Haiyu Zhao
Summary: Chronic caffeine-induced sleep restriction affects the diversity and composition of the gut microbiota in mice and substantially alters the metabolic profiles of the gut microbiome.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agronomy
Gilda Mogor, Atila Francisco Mogor, Giuseppina Pace Pereira Lima, Ricardo Augusto de Oliveira, Joao Carlos Bespalhok Filho
Summary: This study investigates the stimulation of sugarcane bud sprouting using microalgae biomass. A metabolomics approach was used to identify the effect of microalgae on sugarcane sprouting. The results indicate that microalgae biomass promotes bud sprouting and growth, which is related to polyamines in nitrogen metabolism.
Article
Plant Sciences
Octavio Augusto Costa Almeida, Natalia Oliveira de Araujo, Aline Tieppo Nogueira Mulato, Gabriela Felix Persinoti, Mauricio Luis Sforca, Maria Juliana Calderan-Rodrigues, Juliana Velasco de Castro Oliveira
Summary: Plant growth-promoting bacteria (PGPB) release volatile organic compounds (VOCs) that have been proven to promote biomass accumulation in certain crops. However, the effects of VOCs on rice growth have not been studied. This research evaluated the composition and effects of bacterial VOCs on rice growth and metabolism, and identified a bioactive compound, nonan-2-one, that promotes rice growth.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Multidisciplinary Sciences
M. Yu Kochevalina, A. B. Bukharina, V. G. Trunov, A. Pento, O. Morozova, G. A. Kogun', Ya O. Simanovsky, S. M. Nikiforov, E. Rodionova
Summary: Trained detection dogs and a novel laser ionization mass spectrometry method are able to detect chemical differences in urine related to tumor growth and track minor changes over time.
SCIENTIFIC REPORTS
(2022)
Article
Nutrition & Dietetics
Mohamed Madkour, Alexander D. Giddey, Nelson C. Soares, Mohammad H. Semreen, Yasser Bustanji, Falak Zeb, Rabih Halwani, MoezAlIslam E. Faris
Summary: The study aims to investigate the metabolomics changes during the observance of Ramadan diurnal intermittent fasting (RDIF). The results showed that there were significant reductions in some metabolites and increases in others during RDIF. Furthermore, the study found that RDIF significantly affected various metabolic pathways, including histidine metabolism, folate biosynthesis, phenylalanine, tyrosine, and tryptophan biosynthesis, aminoacyltRNA biosynthesis, caffeine metabolism, and vitamin B-6 metabolism.
FRONTIERS IN NUTRITION
(2023)
Article
Endocrinology & Metabolism
Nicholas J. Saner, Matthew J-C. Lee, Jujiao Kuang, Nathan W. Pitchford, Gregory D. Roach, Andrew Garnham, Amanda J. Genders, Tanner Stokes, Elizabeth A. Schroder, Zhiguang Huo, Karyn A. Esser, Stuart M. Phillips, David J. Bishop, Jonathan D. Bartlett
Summary: The study revealed that a five-night period of sleep restriction leads to reductions in mitochondrial respiratory function, sarcoplasmic protein synthesis, and amplitude of skin temperature diurnal rhythms, along with a concurrent reduction in glucose tolerance. However, these detrimental effects were not observed when high-intensity interval exercise (HIIE) was performed during the period of sleep restriction, suggesting HIIE may be an effective intervention to mitigate the negative physiological effects of sleep loss.
MOLECULAR METABOLISM
(2021)
Review
Medicine, Research & Experimental
Allyson K. Palmer, Michael D. Jensen
Summary: Aging and metabolism are closely linked, and age-related changes in body composition are influenced by fundamental aging processes. Sedentary lifestyle exacerbates these changes, but they can be prevented through regular physical activity. This article explores age-related changes in metabolic tissues and overall metabolism in older adults, and discusses therapeutic interventions to maintain healthy metabolism in aging based on human studies.
JOURNAL OF CLINICAL INVESTIGATION
(2022)
Article
Biology
Kosuke Tanioka, Momoko Kayaba, Sayaka Tomishima, Yoko Komada, Yuichi Inoue
Summary: This study examined sleep behaviors and issues in young people in Japan before and after the COVID-19 pandemic. Results showed a significant delay in sleep phase during the pandemic, but improvements were seen in total sleep time, social jetlag, and psychological health after the pandemic.
CHRONOBIOLOGY INTERNATIONAL
(2022)
Article
Multidisciplinary Sciences
Jeremi K. Ochab, Jerzy Szwed, Katarzyna Oles, Anna Beres, Dante R. Chialvo, Aleksandra Domagalik, Magdalena Fafrowicz, Halszka Oginska, Ewa Gudowska-Nowak, Tadeusz Marek, Maciej A. Nowak
Summary: Prolonged periods of sleep restriction have negative impacts on circadian rhythmicity, waking alertness, and cognitive function. Despite a week of recovery, the effects of chronic sleep loss on various measures in the human body are not fully reversed.
Article
Nutrition & Dietetics
Marina Martin, Amaia Rodriguez, Javier Gomez-Ambrosi, Beatriz Ramirez, Sara Becerril, Victoria Catalan, Miguel Lopez, Carlos Dieguez, Gema Fruhbeck, Maria A. Burrell
Summary: Restriction of high-fat diet intake can lead to weight loss and reduced adiposity, as well as improved metabolism; normalization of hypothalamic NPY, AgRP and POMC expression may play a role in this process.
Article
Biochemistry & Molecular Biology
Rohit Rao, Pramod Somvanshi, Elizabeth B. Klerman, Charles Marmar, Francis J. Doyle
Summary: Chronic sleep deficiency is common in modern society and is associated with increased risk of metabolic and other diseases. Cortisol, the primary hormone of the HPA axis, shows significant circadian rhythmicity and is influenced by sleep, wake states, and other physiology. Studies suggest that chronic sleep deficiency may lead to pathophysiological changes through its effects on the HPA axis.
Article
Immunology
Michela Masi-Leone, Stephen Arpadi, Chloe Teasdale, Katharine A. Yuengling, Anthony Mutiti, Mary Mogashoa, Emilia D. Rivadeneira, Elaine J. Abrams, Jennifer Jao
Summary: This study found that higher viral load at ART initiation was associated with poorer growth and lipid outcomes over time for CLHIV under 3 years old. For those aged 3 and above, the increase in pretreatment viral load was linked to different patterns in growth indicators, highlighting the need for individualized interventions based on age groups.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Review
Behavioral Sciences
Jesus Enrique Garcia-Aviles, Rebeca Mendez-Hernandez, Mara A. Guzman-Ruiz, Miguel Cruz, Natali N. Guerrero-Vargas, Javier Velazquez-Moctezuma, Gabriela Hurtado-Alvarado
Summary: Sleep plays a crucial role in learning, memory consolidation, and metabolic function. Sleep restriction may increase the accumulation of Aβ and the risk of developing AD. Chronic sleep restriction can lead to metabolic and cognitive impairments, potentially contributing to the development of AD.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE
(2021)
