Article
Public, Environmental & Occupational Health
Karen Walker-Bone, Geza Benke, Ewan MacFarlane, S. Klebe, Ken Takahashi, Fraser Brims, Malcolm Ross Sim, Tim R. Driscoll
Summary: Mesothelioma, a rare and deadly cancer associated with asbestos exposure, continues to be diagnosed in Australia despite the ban on asbestos since 2003. The Australian Mesothelioma Registry was established to gather comprehensive data on incidence, mortality, and asbestos exposure. Results show a decline in incidence and mortality rates due to effective control of occupational asbestos use, but the rates among women remain stable, suggesting other sources of exposure.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Environmental Sciences
C. Airoldi, C. Magnani, F. Lazzarato, D. Mirabelli, S. Tunesi, D. Ferrante
Summary: This study found an increasing pattern of mesothelioma risk in the area around a big AC factory, with secondary clusters of cases detected due to local exposure points, possibly associated with the use of asbestos materials.
ENVIRONMENTAL HEALTH
(2021)
Article
Environmental Sciences
Yuhe Gao, Jacek M. Mazurek, Yaming Li, David Blackley, David N. Weissman, Shirley V. Burton, Waqas Amin, Douglas Landsittel, Michael J. Becich, Ye Ye
Summary: This study examines the work histories and survival time of patients with suspected exposure to asbestos. The most frequent cases of mesothelioma occurred in patients working in manufacturing, construction, and education services. Males or individuals over 40 tended to work in traditionally asbestos-associated industries, while females or individuals aged 20-40 tended to work in non-traditionally associated industries. The results highlight the importance of considering all potential sources of asbestos exposure when evaluating mesothelioma patients.
ENVIRONMENTAL RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Alessandro Marinaccio, Davide Di Marzio, Carolina Mensi, Dario Consonni, Carmela Gioscia, Enrica Migliore, Carlo Genova, Roberta Rossetto Giaccherino, Silvia Eccher, Stefano Murano, Vera Comiati, Veronica Casotto, Corrado Negro, Lucia Mangone, Lucia Miligi, Sara Piro, Alessia Angelini, Iolanda Grappasonni, Gabriella Madeo, Ilaria Cozzi, Laura Ancona, Tommaso Staniscia, Francesco Carrozza, Domenica Cavone, Luigi Vimercati, Michele Labianca, Federico Tallarigo, Giuseppe Cascone, Massimo Melis, Michela Bonafede, Alberto Scarselli, Alessandra Binazzi
Summary: Mesothelioma incidence surveillance and individual research on asbestos exposure are important for monitoring health effects and preventing exposure risks. Young mesothelioma cases with non-occupational asbestos exposure signal potential clusters of cases.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Environmental Sciences
Trudie Vorster, Julian Mthombeni, Jim TeWaterNaude, James Ian Phillips
Summary: Asbestos mining in South Africa has resulted in asbestos contamination and related diseases. This study investigates the demographics of deceased individuals diagnosed with mesothelioma and explores the connection between mesothelioma histological morphology and asbestos characteristics.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Biology
John E. Till, Harold L. Beck, John D. Boice, H. Justin Mohler, Michael T. Mumma, Jill W. Aanenson, Helen A. Grogan
Summary: This study provides the first quantitative assessment of asbestos-related mesothelioma among military personnel who participated in above-ground nuclear weapons testing. The results show that enlisted naval personnel who participated in these tests had a significantly increased risk of developing mesothelioma, while there was no increased risk observed in other services or among naval personnel with minimal exposure to asbestos.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2022)
Article
Health Care Sciences & Services
Veronica Filetti, Carla Loreto, Luca Falzone, Claudia Lombardo, Emanuele Cannizzaro, Sergio Castorina, Caterina Ledda, Venerando Rapisarda
Summary: This study aimed to validate the diagnostic significance of hsa-miR-323a-3p, hsa-miR-101-3p, and hsa-miR-20b-5p in MM patients exposed to FE. Results showed the down-regulation of these miRNAs in MM cases, with hsa-miR-323a-3p and hsa-miR-20b-5p having diagnostic value for MM. Computational analysis suggested a potential prognostic role of hsa-miR-101-3p in MM patients, correlating higher expression with increased overall survival.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Environmental Sciences
Suresh Moolgavkar, Ellen T. Chang, E. Georg Luebeck
Summary: The current understanding is that cancer is caused by mutations in a few crucial genes, which has implications for the epidemiology of cancer. These include the impact of age on cancer risk, the role of inherited tumor predisposition syndromes, and the interaction of genetics and environmental exposures on cancer risk.
ENVIRONMENTAL RESEARCH
(2023)
Article
Oncology
Yuri Kitamura, Ling Zha, Rong Liu, Masayuki Shima, Tomoki Nakaya, Norio Kurumatani, Shinji Kumagai, Junko Goji, Tomotaka Sobue
Summary: This study aimed to quantify the risk of mesothelioma death associated with neighborhood asbestos exposure, and found a dose-dependent relationship between neighborhood exposure and mesothelioma death risk, with higher risks in the highest quintile category.
Article
Cardiac & Cardiovascular Systems
Daniel Wang, Yung Hsuan Wang, Sung Chao Chu
Summary: The article presents a case report of an early multidisciplinary clinical approach to diagnose and manage PPM, considering occupational asbestos exposure history and clinical symptoms. Bevacizumab-based chemotherapy is shown to be an option for the treatment of PPM.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Zhen Zhai, Jian Ruan, Yi Zheng, Dong Xiang, Na Li, Jingjing Hu, Jianfei Shen, Yujiao Deng, Jia Yao, Peng Zhao, Shuqian Wang, Si Yang, Linghui Zhou, Ying Wu, Peng Xu, Lijuan Lyu, Jun Lyu, Raymond Bergan, Tianhui Chen, Zhijun Dai
Summary: The incidence and mortality of mesothelioma are continuously increasing worldwide, especially in resource-limited regions with low sociodemographic index levels. Governments and medical institutions should consider formulating optimal policies and strategies for the targeted prevention and management of mesothelioma based on these findings.
Article
Public, Environmental & Occupational Health
A. Scarselli, A. Marinaccio, S. Iavicoli
Summary: The study aimed to estimate the potential health impact of naturally occurring asbestos from ophiolitic outcrops in certain areas of Calabria, southern Italy. By analyzing employment, compensation, and mortality data, statistically significant excess risks were observed in several municipalities, some of which were located in areas where asbestos outcrops had been identified.
Article
Public, Environmental & Occupational Health
Pierangela Grignani, Silvia Damiana Visona, Maria Vittoria Fronda, Paola Borrelli, Maria Cristina Monti, Barbara Bertoglio, Adelaide Conti, Paolo Fattorini, Carlo Previdere
Summary: Asbestos-related diseases, including malignant mesothelioma (MM), remain a significant global public health concern. This study investigates the relationship between six SNPs involved in iron metabolism and MM susceptibility/protection after asbestos exposure. The findings suggest that these SNPs are not useful markers for individual susceptibility to mesothelioma.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Biochemistry & Molecular Biology
Veronica Filetti, Claudia Lombardo, Carla Loreto, George Dounias, Massimo Bracci, Serena Matera, Lucia Rapisarda, Venerando Rapisarda, Caterina Ledda, Ermanno Vitale
Summary: Environmental exposure to fibers of respirable size, including fluoro-edenite, has been found to cause chronic respiratory diseases and carcinogenic effects in humans. This is a public health issue that requires the identification of biomarkers for assessing the health status of individuals exposed to fluoro-edenite fibers and for early diagnosis of malignant pleural mesothelioma in asymptomatic patients.
Review
Biochemistry & Molecular Biology
Phillip Munson, Arti Shukla
Summary: This review summarizes the role of exosomes in the development of malignant mesothelioma (MM), and discusses their potential in detection and treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
