Article
Virology
Caroline Deshayes, Anne-Sophie Gosselin-Grenet, Mylene Ogliastro, Bruno Lapied, Veronique Apaire-Marchais
Summary: A novel strategy in pest management involves using virus-like particles as synergistic agents to enhance the efficacy of insecticides.
Article
Chemistry, Physical
Qi Xu, Han Hu, Zhimin Mo, Tianyou Chen, Qianyuan He, Zushun Xu
Summary: Lenvatinib has replaced Sorafenib as the preferred treatment for hepatocellular carcinoma. To enhance its efficacy, researchers developed nanoparticle delivery systems using copper sulfide nanocrystals and gold nanoparticles wrapped in galactosamine conjugated poly(lactide-co-glycolide). These nanoparticles exhibit stability and release the drug rapidly in the tumor microenvironment, aided by near-infrared-II photothermal effect. The combination therapy significantly improves the efficacy of Lenvatinib and offers a multifunctional delivery system for enhanced HCC treatment.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Business
Matilda Dorotic, Dennis Fok, Peter C. Verhoef, Tammo H. A. Bijmolt
Summary: The study found that in loyalty programs, cannibalization among partners occurs more frequently than positive synergies, leading to a richer-get-richer effect for high-penetration partners.
JOURNAL OF THE ACADEMY OF MARKETING SCIENCE
(2021)
Article
Green & Sustainable Science & Technology
S. Rezaei, J. Behnamian
Summary: This paper investigates a competitive model in partnership supply networks and proposes a solving approach based on a combination of the Benders Decomposition method and Particle Swarm Optimization algorithm. Experimental results demonstrate the superiority of the proposed method in large-scale instances.
JOURNAL OF CLEANER PRODUCTION
(2022)
Review
Immunology
Nicolas Personnic, Patricia Doublet, Sophie Jarraud
Summary: This mini-review discusses the interplay between bacteria's persistent invasion and cellular defense mechanisms, as well as the underlying heterogeneity involved.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Multidisciplinary Sciences
Liying Xu, Jiadi Zhu, Bing Chen, Zhen Yang, Keqin Liu, Bingjie Dang, Teng Zhang, Yuchao Yang, Ru Huang
Summary: This article introduces a multi-agent hardware system that utilizes distributed Ag nanoclusters as physical agents to achieve parallel complex computing. The proposed system efficiently expresses and processes information through collaboration and competition, replacing exhaustive operations with self-organization of a physical network, thereby significantly reducing computational complexity.
NATURE COMMUNICATIONS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Giuseppe Carlucci, Robin Ippisch, Roger Slavik, Ashley Mishoe, Joseph Blecha, Shaojun Zhu
Summary: This article discusses the collaboration between UCLA and UCSF in developing the new drug Ga-68-PSMA-11 for prostate cancer PET imaging, the FDA approval process, and key CMC information provided for ANDA submission.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Article
Biotechnology & Applied Microbiology
Peiyu Liu, Yan Liu, Xinyi Ren, Zhifei Zhang, Xiang Zhao, Andrew P. Roberts, Yongxin Pan, Jinhua Li
Summary: The newly discovered magnetotactic spirillum XQGS-1 from Xingqinggong Lake in Xi'an City, Shaanxi Province, China, represents a novel genus of the Alphaproteobacteria class. In addition to forming magnetite crystals, XQGS-1 cells also biomineralize submicrometer calcium carbonate and calcium phosphate granules intracellularly, indicating that magnetotactic bacteria are an important microbial group for intracellular calcium carbonate and calcium phosphate biomineralization.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Entomology
Maiqun Gu, Jiaxin Tian, Yulu Lou, Jia Ran, Amr Mohamed, Nemat O. Keyhani, Stefan Jaronski, Guangmin Wang, Xuanyu Chen, Lian-Sheng Zang, Wei Zhang
Summary: The study found that the pathogenic fungus M. rileyi has good control effect on fall armyworm. Field trials showed that application of M. rileyi granules alone can significantly reduce fall armyworm larval populations and plant damage, and combining with other control measures can further improve the effect.
ENTOMOLOGIA GENERALIS
(2023)
Review
Medicine, General & Internal
Imma Forzano, Pasquale Mone, Gaetano Mottola, Urna Kansakar, Luigi Salemme, Antonio De Luca, Tullio Tesorio, Fahimeh Varzideh, Gaetano Santulli
Summary: Current therapeutic strategies for AHF rely on traditional inotropic agents, which often have adverse effects. There is a need for new and safer approaches. Istaroxime, a novel compound unrelated to cardiac glycosides, is being studied for AHF treatment. Its effects are related to activation of SERCA2a and inhibition of NKA activity, with advantages of lower arrhythmogenic action and increased systolic blood pressure without affecting heart rate. However, it has a limited half-life and associated adverse effects.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Computer Science, Artificial Intelligence
Wei Zhang, Andrea Valencia, Ni-Bin Chang
Summary: This article provides a comprehensive review of the application of ML in ABMs, focusing on four major scenarios and investigating related algorithms, frameworks, procedures, and applications. ML can improve prediction in ABMs by balancing variance and bias, and it can enhance sequential decision-making by reinforcing behavioral intervention for microagents and macrolevel policymakers.
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
(2023)
Article
Chemistry, Physical
Junzong Chen, Miaojuan Qiu, Shiqiang Zhang, Binbin Li, Dong Li, Xiuyu Huang, Zhirong Qian, Jing Zhao, Zhiyong Wang, Di Tang
Summary: In this study, amino-capped polyamidoamine dendrimer was used as a macromolecular template to form amino-modified calcium phosphate hollow sphere for drug delivery application. The system loaded with 5-fluorouracil performed synergistic cancer chemotherapy by inducing calcium overload and reactive oxygen species accumulation in cancer cells, leading to apoptosis. The delivery system showed high tumor inhibition via chemotherapy with minimal impact on normal cells and organs, demonstrating good biocompatibility.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Environmental Sciences
Leandro P. Franca, Ana Claudia F. Amaral, Aline de S. Ramos, Jose Luiz P. Ferreira, Ana Clara B. Maria, Kelson Mota T. Oliveira, Earle S. Araujo, Adjane Dalvana S. Branches, Jonathas N. Silva, Noam G. Silva, Gabriel de A. Barros, Francisco Celio M. Chaves, Wanderli P. Tadei, Jefferson Rocha de A. Silva
Summary: Mosquitoes, particularly Aedes aegypti and Aedes albopictus, are important vectors of diseases like dengue and Zika worldwide. Essential oils extracted from plants, such as Piper capitarianum, show insecticidal potential against these mosquitoes and are environmentally friendly.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Engineering, Biomedical
Shuai Guo, Wei Xiong, Jiaoyang Zhu, Jie Feng, Ruilong Zhou, Qingdeng Fan, Qianqian Zhang, Zongheng Li, Jing Yang, Huimin Zhou, Peiwei Yi, Yanqiu Feng, Sugeun Yang, Xiaozhong Qiu, Yikai Xu, Zheyu Shen
Summary: In this study, a STING pathway-activatable contrast agent was developed for magnetic resonance imaging (MRI)-guided tumor immunoferroptosis synergistic therapy. The effectiveness and biosafety of this therapy were demonstrated by in vivo investigations, and the mechanisms of action were studied using various indicators.
Article
Green & Sustainable Science & Technology
Surasak Jotaworn, Vilas Nitivattananon, Kyoko Kusakabe, Wenchao Xue
Summary: This study explores the synergies in waste management services in Thailand's Eastern Economic Corridor, finding different strategies and challenges for the public and private sectors. Collaboration between the two sectors can lead to more effective waste management.
Review
Pharmacology & Pharmacy
Samuel Legeay, Nicolas Clere, Veronique Apaire-Marchais, Sebastien Faure, Bruno Lapied
EUROPEAN JOURNAL OF PHARMACOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Javier Pitti Caballero, Laurence Murillo, Olivier List, Guillaume Bastiat, Annie Flochlay-Sigognault, Frank Guerino, Corinne Lefrancois, Nolwenn Lautram, Bruno Lapied, Veronique Apaire-Marchais
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Milena Jankowska, Bruno Lapied, Waldemar Jankowski, Maria Stankiewicz
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Milena Jankowska, Justyna Wisniewska, Lukasz Faltynowicz, Bruno Lapied, Maria Stankiewicz
Article
Multidisciplinary Sciences
Eleonore Moreau, Karolina Mikulska-Ruminska, Mathilde Goulu, Stephane Perrier, Caroline Deshayes, Maria Stankiewicz, Veronique Apaire-Marchais, Wieslaw Nowak, Bruno Lapied
SCIENTIFIC REPORTS
(2020)
Article
Biology
Stephane Perrier, Eleonore Moreau, Caroline Deshayes, Marine El-Adouzi, Delphine Goven, Fabrice Chandre, Bruno Lapied
Summary: Researchers found that nAChRs and intracellular calcium concentration provide a compensatory mechanism for the neurons of two resistant mosquito strains, AcerKis and KdrKis, to insecticide exposure.
COMMUNICATIONS BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Beata Niklas, Bruno Lapied, Wieslaw Nowak
Summary: This study investigated compounds that target human and insect muscarinic acetylcholine receptors, which are novel targets for synergistic agents in pest control. The researchers used molecular docking and molecular dynamics simulation to study the conformational changes of these receptors in response to different ligands and proposed a potential strategy using bitopic ligands for better insect control.
Article
Zoology
Randy Atencio, Anovel Barba, Ruben Collantes, Javier Pitti, Jorge Munoz, Bruno A. S. de Medeiros, Jennifer Giron
Summary: A new species of broad-nosed weevil, Epicaerus panamensis, is described in this study. The specimens were collected on or around potato cultivars in Tierras Altas de Chiriqui, Panama. Detailed images of the field, habitus, male and female genitalia, as well as feeding damage caused by the weevils on potato leaves, are provided. The species is compared to a closely related species, Epicaerus inaequalis, and discussed in terms of their morphological affinities and taxonomic placement.
Article
Virology
Caroline Deshayes, Anne-Sophie Gosselin-Grenet, Mylene Ogliastro, Bruno Lapied, Veronique Apaire-Marchais
Summary: A novel strategy in pest management involves using virus-like particles as synergistic agents to enhance the efficacy of insecticides.
Article
Entomology
James Devillers, Jean-Philippe David, Benoit Barres, Haoues Alout, Bruno Lapied, Sebastien Chouin, Isabelle Dusfour, Catherine Billault, Farida Mekki, Isabelle Attig, Vincent Corbel
Summary: The present work proposes an integrated plan of resistance surveillance in France and in the French Overseas territories to provide appropriate responses to the situation. The plan includes periodic monitoring of insecticide resistance at the population level using various approaches and a stratification of resistance risk at the territory level to adjust surveillance and vector control actions.
Review
Biochemistry & Molecular Biology
Caroline Deshayes, Myriam Siegwart, David Pauron, Josy-Anne Froger, Bruno Lapied, Veronique Apaire-Marchais
CURRENT MEDICINAL CHEMISTRY
(2017)
Article
Neurosciences
Bruno Lapied, Antoine Defaix, Maria Stankiewicz, Eleonore Moreau, Valerie Raymond
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2017)
Article
Biology
Erika Machtinger, Karen C. Poh, Risa Pesapane, Danielle M. Tufts
Summary: Vector-borne diseases, transmitted by insects, are a significant threat to global human and animal health. Their emergence is influenced by factors such as environmental changes, host characteristics, and human behavior. The One Health approach is necessary to comprehensively investigate tick-borne diseases and understand the complex interactions between environmental, animal, and human health.
CURRENT OPINION IN INSECT SCIENCE
(2024)
Article
Biology
Pablo Urbaneja-Bernat, Alejandro Tena, Joel Gonzalez-Cabrera, Cesar Rodriguez-Saona
Summary: This article reviews the potential role of plant guttation as a food source for natural enemies, discussing its nutritional value, effects on insect communities, and potential use in conservation biological control.
CURRENT OPINION IN INSECT SCIENCE
(2024)
Article
Biology
Alina A. Mikhailova, Sarah Rinke, Mark C. Harrison
Summary: The genomes of eusocial insects allow the production and regulation of highly distinct phenotypes, largely independent of genotype. Eusociality has evolved convergently in at least three insect orders, but eusocial phenotypes show remarkable similarity. Increased regulatory complexity and the adaptive evolution of chemical communication are common genomic signatures of eusociality. Colony life itself can shape genomes of divergent taxa in a similar manner.
CURRENT OPINION IN INSECT SCIENCE
(2024)
Article
Biology
Dequn Teng, Wei Zhang
Summary: Butterfly wings, with their rich phenotypic diversity and complex biological functions, serve as a crucial system for studying the genetic basis and evolution of phenotypic diversification. Recent studies have revealed the complex functions and genetic and environmental factors involved in determining wing patterns. These factors lead to inter-specific divergence, genetic polymorphism, and phenotypic plasticity, often controlled by key genes. Gene co-option has also been identified as an important mechanism for functional complexity and evolutionary novelty. However, further research is needed for a systematic and comprehensive understanding.
CURRENT OPINION IN INSECT SCIENCE
(2024)