Survivin-targeted immunotherapy drives robust polyfunctional T cell generation and differentiation in advanced ovarian cancer patients

Immunologic response to the survivin-derived multi-epitope vaccine EMD640744 in patients with advanced solid tumors

(2014) Volker Lennerz et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Clearance of depot vaccine SPIO-labeled antigen and substrate visualized using MRI

(2014) Kimberly D. Brewer et al.   VACCINE

Apoptosis-Regulated Low-Avidity Cancer-Specific CD8+ T Cells Can Be Rescued to Eliminate HER2/neu-Expressing Tumors by Costimulatory Agonists in Tolerized Mice

(2014) C. M. Black et al.   Cancer Immunology Research

Metronomic cyclophosphamide enhances HPV16E7 peptide vaccine induced antigen-specific and cytotoxic T-cell mediated antitumor immune response

(2014) Genevieve M Weir et al.   OncoImmunology

Activation, dysfunction and retention of T cells in vaccine sites after injection of incomplete Freund’s adjuvant, with or without peptide

(2013) Elise P. Salerno et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Lineage relationship of effector and memory T cells

(2013) Nicholas P Restifo et al.   CURRENT OPINION IN IMMUNOLOGY

Tumor-specific CD4+T cells maintain effector and memory tumor-specific CD8+T cells

(2013) Sarah E. Church et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Checkpoint blocking antibodies in cancer immunotherapy

(2013) Chrisann Kyi et al.   FEBS LETTERS

Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion

(2013) Yared Hailemichael et al.   NATURE MEDICINE

CD4+ T Cells Play a Critical Role in the Generation of Primary and Memory Antitumor Immune Responses Elicited by SA-4-1BBL and TAA-Based Vaccines in Mouse Tumor Models

(2013) Rajesh K. Sharma et al.   PLoS One

Myeloid derived suppressor cells

(2013) Todd J. Waldron et al.   OncoImmunology

Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma

(2012) Jürgen C. Becker et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial

(2012) Eva Ellebaek et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Regulatory T-cell Modulation Using Cyclophosphamide in Vaccine Approaches: A Current Perspective

(2012) D. T. Le et al.   CANCER RESEARCH

First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients

(2012) Neil L Berinstein et al.   Journal of Translational Medicine

Immune tolerance against HBV can be overcome in HBV transgenic mice by immunization with dendritic cells pulsed by HBVsvp

(2012) Mohamed M.S. Farag et al.   VACCINE

PGE2-Induced CXCL12 Production and CXCR4 Expression Controls the Accumulation of Human MDSCs in Ovarian Cancer Environment

(2011) N. Obermajer et al.   CANCER RESEARCH

Prognostic significance of tumor-infiltrating T cells in ovarian cancer: A meta-analysis

(2011) Wei-Ting Hwang et al.   GYNECOLOGIC ONCOLOGY

The HIV/AIDS Vaccine Candidate MVA-B Administered as a Single Immunogen in Humans Triggers Robust, Polyfunctional, and Selective Effector Memory T Cell Responses to HIV-1 Antigens

(2011) C. E. Gomez et al.   JOURNAL OF VIROLOGY

Cancer immunotherapy – revisited

(2011) W. Joost Lesterhuis et al.   NATURE REVIEWS DRUG DISCOVERY

Immune Modulation by Chemotherapy or Immunotherapy to Enhance Cancer Vaccines

(2011) Genevieve M. Weir et al.   Cancers

Potential Target Antigens for a Universal Vaccine in Epithelial Ovarian Cancer

(2010) Renee Vermeij et al.   Clinical & Developmental Immunology

From Vaccines to Memory and Back

(2010) Federica Sallusto et al.   IMMUNITY

A Novel Breast/Ovarian Cancer Peptide Vaccine Platform That Promotes Specific Type-1 but not Treg/Tr1-type Responses

(2010) Mohan Karkada et al.   JOURNAL OF IMMUNOTHERAPY

The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

(2009) M. A. Cheever et al.   CLINICAL CANCER RESEARCH