CD11b+Ly6G+ cells inhibit tumor growth by suppressing IL-17 production at early stages of tumorigenesis

Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression

(2013) Inbal Mishalian et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases

(2013) M. J. Riese et al.   CANCER RESEARCH

Enhancement of Antitumor Immunity in Lung Cancer by Targeting Myeloid-Derived Suppressor Cell Pathways

(2013) A. Sawant et al.   CANCER RESEARCH

Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis

(2013) D. E. Sanford et al.   CLINICAL CANCER RESEARCH

Inhibition of IL-17A in Tumor Microenvironment Augments Cytotoxicity of Tumor-Infiltrating Lymphocytes in Tumor-Bearing Mice

(2013) Keiji Hayata et al.   PLoS One

Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

(2012) Claudia A. Dumitru et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Tumor-associated neutrophils: friend or foe?

(2012) Z. G. Fridlender et al.   CARCINOGENESIS

Myeloid Cells Obtained from the Blood but Not from the Tumor Can Suppress T-cell Proliferation in Patients with Melanoma

(2012) A. Gros et al.   CLINICAL CANCER RESEARCH

Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice

(2012) Junjie Mei et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil Expression of Fas Ligand and Perforin Directs Effector CD8 T Cell Infiltration into Antigen-Challenged Skin

(2012) D. D. Kish et al.   JOURNAL OF IMMUNOLOGY

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils

(2012) Zvi G. Fridlender et al.   PLoS One

Myeloid Suppressor Cell Depletion Augments Antitumor Activity in Lung Cancer

(2012) Minu K. Srivastava et al.   PLoS One

Protumor and antitumor functions of neutrophil granulocytes

(2012) Sven Brandau et al.   Seminars in Immunopathology

The pros and cons of chemokines in tumor immunology

(2012) Antonella Viola et al.   TRENDS IN IMMUNOLOGY

Redirecting neutrophils against bladder cancer cells by BCG and Smac mimetic combination

(2012) Goodwin Jinesh G. et al.   OncoImmunology

IL-17A is a central regulator of lung tumor growth

(2012) Sarah Reppert et al.   OncoImmunology

Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung

(2011) Zvi Granot et al.   CANCER CELL

Tumor-Associated Neutrophils: New Targets for Cancer Therapy

(2011) A. D. Gregory et al.   CANCER RESEARCH

Increased IL-17-producing CD4+ T cells in patients with esophageal cancer

(2011) Deyu Chen et al.   CELLULAR IMMUNOLOGY

On the dual roles and polarized phenotypes of neutrophils in tumor development and progression

(2011) H. Piccard et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

IL-17A and TNF-  Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro

(2011) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism

(2011) Jeremy D. Waight et al.   PLoS One

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer

(2011) S. Reppert et al.   Nature Communications

Chemokines

(2010) Steven M. Dubinett et al.   CANCER JOURNAL

Increased prevalence of interleukin-17-producing CD4+ tumor infiltrating lymphocytes in human oral squamous cell carcinoma

(2010) Jang-Jaer Lee et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Successful Colon Cancer Eradication after Chemoimmunotherapy Is Associated with Profound Phenotypic Change of Intratumoral Myeloid Cells

(2010) J. Medina-Echeverz et al.   JOURNAL OF IMMUNOLOGY

IL-17 Promotes Tumor Development through the Induction of Tumor Promoting Microenvironments at Tumor Sites and Myeloid-Derived Suppressor Cells

(2010) Donggou He et al.   JOURNAL OF IMMUNOLOGY

Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties

(2010) Sven Brandau et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Regulatory Myeloid Suppressor Cells in Health and Disease

(2009) S. Nagaraj et al.   CANCER RESEARCH

Presence of Intratumoral Neutrophils Is an Independent Prognostic Factor in Localized Renal Cell Carcinoma

(2009) Hanne Krogh Jensen et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

(2009) G. Solinas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Polymorphonuclear neutrophils and cancer: Intense and sustained neutrophilia as a treatment against solid tumors

(2009) Juan Carlos Souto et al.   MEDICINAL RESEARCH REVIEWS

The role of CXC chemokines and their receptors in cancer

(2008) Jo Vandercappellen et al.   CANCER LETTERS

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

(2008) Wenjun Ouyang et al.   IMMUNITY

Macrophages define the invasive microenvironment in breast cancer

(2008) Jeffrey W. Pollard   JOURNAL OF LEUKOCYTE BIOLOGY