Review
Urology & Nephrology
Arnaud Devresse, Sophie Gohy, Arnaud Robert, Nada Kanaan
Summary: Smoking has negative impacts on kidney transplantation outcomes, with guidelines strongly recommending quitting before transplantation. Nicotine addiction is a complex disease, with smoking cessation programmes proving effective in the general population.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Substance Abuse
Philip Tonnesen, David Lawrence, Serena Tonstad
Summary: This post hoc analysis of EAGLES data found that smokers with smoking-related diseases had lower continuous abstinence rates compared to those without these comorbidities. The use of smoking cessation medication was identified as the strongest predictor of continuous abstinence.
TOBACCO INDUCED DISEASES
(2022)
Article
Substance Abuse
Rukshar K. Gobarani, Jenni Ilomaki, Stephen Wood, Michael J. Abramson, Billie Bonevski, Johnson George
Summary: This study examined the use of smoking cessation medications in Australia and found that varenicline was more commonly dispensed compared to nicotine replacement therapy and bupropion. The study also revealed that individuals who received varenicline were generally healthier.
Article
Pharmacology & Pharmacy
Paulo Roberto Xavier Tomaz, Thuane Sales Goncalves, Juliana Rocha Santos, Jaqueline Scholz, Tania Ogawa Abe, Patricia Viviane Gaya, Eduardo Costa Figueiredo, Henrique Dipe de Faria, Isarita Martins, Ana Miguel Fonseca Pego, Beatriz Aparecida Bismara, Mauricio Yonamine, Alexandre Costa Pereira, Paulo Caleb Lima Santos Junior
Summary: This study aimed to evaluate the application of nicotine metabolite ratio (NMR) in Brazilian smoking patients and analyze its association with smoking characteristics. The findings contribute to the development of personalized smoking cessation treatments and improvement of success rates.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Substance Abuse
Helena Zhang, Tara Mansoursadeghi-Gilan, Sarwar Hussain, Scott Veldhuizen, Bernard Le Foll, Peter Selby, Laurie Zawertailo
Summary: This study evaluated the effectiveness of an online treatment using first-line prescription medications for smoking cessation. The results showed that the varenicline group had higher 7-day quit rates compared to the bupropion group, and this difference persisted in the follow-up periods. However, the varenicline group also reported more adverse events.
DRUG AND ALCOHOL DEPENDENCE
(2022)
Review
Pharmacology & Pharmacy
Sabina Antonela Antoniu, Ioana Buculei, Florin Mihaltan, Radu Crisan Dabija, Antigona Carmen Trofor
Summary: The article discusses the clinical data of main studies evaluating smoking cessation therapies for COPD patients, starting from seminal studies like the Lung Health Study to more recent ones. Despite the high impact on disease progression and demonstrated benefits of pharmacological therapies, smoking cessation remains challenging in COPD. Potential approaches to increase success rates include prolonging treatment duration, combination therapy, or sequential pharmacotherapy.
EXPERT OPINION ON PHARMACOTHERAPY
(2021)
Review
Medicine, General & Internal
Nancy A. Rigotti, Gina R. Kruse, Jonathan Livingstone-Banks, Jamie Hartmann-Boyce
Summary: Cigarette smoking is the leading preventable cause of death in the US, and quitting smoking can potentially add up to 10 years of life expectancy. Most smokers want to quit and usually make multiple attempts before achieving long-term abstinence. A combination of behavioral counseling and medication, particularly varenicline, is the most effective treatment for smoking cessation.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Substance Abuse
Catherine Lobbe, Jade Bahnisch, Chenxi Lin, Apo Demirkol, Bridin Murnion
Summary: This study investigates the experience, knowledge, and attitudes of patients and clinicians in two public Australian opioid agonist treatment (OAT) clinics towards smoking cessation medications (nicotine replacement therapy [NRT], bupropion, and varenicline) and e-cigarettes. The findings show that patients prefer e-cigarettes but are more likely to consider using NRT. Patients report high rates of tobacco cessation planning but low rates of intervention. Clinicians are aware of the high prevalence of tobacco use but have low rates of smoking cessation interventions. Improving knowledge about tobacco cessation medications among patients and clinicians could enhance smoking cessation interventions and the usage of approved medications.
DRUG AND ALCOHOL REVIEW
(2023)
Article
Obstetrics & Gynecology
Henry R. Kranzler, Yukiko Washio, Leah R. Zindel, E. Paul Wileyto, Sindhu Srinivas, Dennis J. Hand, Matthew Hoffman, Cheryl Oncken, Robert A. Schnoll
Summary: This study evaluated the efficacy and safety of sustained-release bupropion for smoking cessation among pregnant women, finding that bupropion was not effective in promoting smoking cessation in this cohort. While bupropion use did not increase the risk of pregnancy complications when initiated in the second trimester, it also did not increase the likelihood of smoking cessation among pregnant women.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Article
Substance Abuse
Nayoung Kim, Danielle E. McCarthy, Megan E. Piper, Timothy B. Baker
Summary: This study compared the effects of varenicline and combination nicotine replacement therapy (C-NRT) with nicotine patch monotherapy on different phases of smoking cessation. Varenicline showed greater suppression of craving and smoking expectancies pre-cessation, while C-NRT mainly reduced craving and expectancies changes during cessation.
Review
Health Care Sciences & Services
Merel Keijsers, Maria Cecilia Vega-Corredor, Melanie Tomintz, Simon Hoermann
Summary: Virtual reality technologies have been proposed to enhance smoking cessation therapy, with cue exposure therapy being the most studied intervention. However, the long-term effects are inconsistent. Behavioral therapies like approach-avoidance tasks or gamified interventions have shown positive results.Future research should focus on multicomponent interventions and include control groups for validity.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Substance Abuse
Emma Beard, Sarah E. Jackson, Robert M. Anthenelli, Neal L. Benowitz, Lisa St. Aubin, Thomas McRae, David Lawrence, Cristina Russ, Alok Krishen, A. Eden Evins, Robert West
Summary: The study used Bayes factors for secondary analysis, showing that the use of varenicline, bupropion, or nicotine patches for smoking cessation does not increase the risk of neuropsychiatric adverse events compared to placebo in the global smoking cessation study, especially for smokers without a history of psychiatric disorders.
Review
Medicine, General & Internal
Carrie D. Patnode, Jillian T. Henderson, Erin L. Coppola, Joy Melnikow, Shauna Durbin, Rachel G. Thomas
Summary: This systematic review examined the effectiveness and safety of pharmacotherapy, behavioral interventions, and electronic cigarettes for tobacco cessation among adults, including pregnant persons. The results showed that a variety of interventions are effective in increasing smoking cessation rates in nonpregnant adults, while behavioral interventions are effective in pregnant women, but data on pharmacotherapy are limited.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Psychology, Clinical
Kangle Guo, Shizhong Wang, Xue Shang, E. Fenfen, Liangying Hou, Jieyun Li, Yanfei Li, Kehu Yang, Xiuxia Li
Summary: This study conducted a network meta-analysis to evaluate the effects of varenicline (VAR), bupropion (BUP), and nicotine replacement therapy (NRT) on smoking cessation. The results showed that VAR, BUP, and NRT alone were more effective than placebo in increasing the odds of smoking abstinence. Combined interventions were superior to monotherapy, and VAR combined with other interventions had the best smoking cessation effect.
ADDICTIVE BEHAVIORS
(2022)
Review
Multidisciplinary Sciences
Lucy Phillips, Ross Thomson, Tom Coleman-Haynes, Sue Cooper, Felix Naughton, Lisa Mcdaid, Joanne Emery, Tim Coleman
Summary: This study conducted a systematic scoping review to determine the number and nature of offspring outcomes studied following nicotine exposure to pregnant non-human mammals. The results showed that the most frequently studied outcomes were changes in the brain, physical parameters, and the respiratory system. Systematic reviews focusing on these areas may contribute to a better understanding of the impacts of gestational nicotine exposure on offspring.
