Disease-modifying treatments for Alzheimer’s disease

GSK-3 Inhibitors: A Ray of Hope for the Treatment of Alzheimer's Disease?

(2017) Ana Martinez et al.   JOURNAL OF ALZHEIMERS DISEASE

Phosphorylated Tau: Toxic, Protective, or None of the Above

(2017) Rudy J. Castellani et al.   JOURNAL OF ALZHEIMERS DISEASE

Drug Development Based on the Metals Hypothesis of Alzheimer's Disease

(2017) Ashley I. Bush   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Stress in Diabetes and Alzheimer's Disease

(2017) V. Prakash Reddy et al.   JOURNAL OF ALZHEIMERS DISEASE

Effectiveness of Cholinesterase Inhibitors and Memantine for Treating Dementia: Evidence Review for a Clinical Practice Guideline

(2013) Parminder Raina et al.   ANNALS OF INTERNAL MEDICINE

Intravenous Immunoglobulins as a Treatment for Alzheimerʼs Disease

(2010) Richard Dodel et al.   DRUGS

Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe

(2010) H. H. Feldman et al.   NEUROLOGY

Cholesterol in Alzheimers Disease: Unresolved Questions

(2009) Massimo Stefani et al.   Current Alzheimer Research

Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation

(2009) Yoshiari Shimmyo et al.   NEUROREPORT

O3-04-05: Clinical trials of bapineuzumab, a beta-amyloid-targeted immunotherapy in patients with mild to moderate Alzheimer's disease

(2008) Michael Grundman et al.   Alzheimers & Dementia

The Atorvastatin/Donepezil in Alzheimer’s Disease Study (LEADe): Design and baseline characteristics

(2008) Roy W. Jones et al.   Alzheimers & Dementia

Phase 2 Safety Trial Targeting Amyloid β Production With a γ-Secretase Inhibitor in Alzheimer Disease

(2008) Adam S. Fleisher et al.   ARCHIVES OF NEUROLOGY

Identification of pharmacophore model, synthesis and biological evaluation of N-phenyl-1-arylamide and N-phenylbenzenesulfonamide derivatives as BACE 1 inhibitors

(2008) Wenhai Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fatty acids, lipid metabolism and Alzheimer pathology

(2008) Carlijn R. Hooijmans et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease

(2008) Paul S. Aisen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

NewN4-substituted piperazine naphthamide derivatives as BACE-1 inhibitors

(2008) Y. Laras et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Etazolate, a neuroprotective drug linking GABAAreceptor pharmacology to amyloid precursor protein processing

(2008) Maryline Marcade et al.   JOURNAL OF NEUROCHEMISTRY

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

(2008) Clive Holmes et al.   LANCET

Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

(2008) Lars Lannfelt et al.   LANCET NEUROLOGY

Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial

(2008) Gordon K Wilcock et al.   LANCET NEUROLOGY

Therapeutic Strategies for Alzheimer’s Disease

(2008) Donna M. Barten et al.   MOLECULAR NEUROBIOLOGY

Tau-based treatment strategies in neurodegenerative diseases

(2008) Anja Schneider et al.   Neurotherapeutics

In vitroBACE-1 Inhibitory Phenolic Components from the Seeds ofPsoralea corylifolia

(2008) Yeon Choi et al.   PLANTA MEDICA