Predictive and prognostic molecular markers for cancer medicine

Spanish customized adjuvant trial (SCAT) based on BRCA1 mRNA levels

(2017) M. Cobo et al.   JOURNAL OF CLINICAL ONCOLOGY

Personalized Genetic Prediction: Too Limited, Too Expensive, or Too Soon?

(2013) John P.A. Ioannidis   ANNALS OF INTERNAL MEDICINE

Direct Profiling of Cancer Biomarkers in Tumor Tissue Using a Multiplexed Nanostructured Microelectrode Integrated Circuit

(2009) Zhichao Fang et al.   ACS Nano

Multigene Classifiers, Prognostic Factors, and Predictors of Breast Cancer Clinical Outcome

(2009) Jeffrey S. Ross   ADVANCES IN ANATOMIC PATHOLOGY

Circulating and Disseminated Tumor Cells in the Management of Breast Cancer

(2009) Jeffrey S. Ross et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Emerging Technologies for Assessing HER2 Amplification

(2009) Frédérique Penault-Llorca et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer

(2009) S. J. Cohen et al.   ANNALS OF ONCOLOGY

COLD-PCR: a new platform for highly improved mutation detection in cancer and genetic testing

(2009) Jin Li et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development

(2009) M.A. Karsdal et al.   BIOMARKERS

Methods comparison for high-resolution transcriptional analysis of archival material on Affymetrix Plus 2.0 and Exon 1.0 microarrays

(2009) Kim M. Linton et al.   BIOTECHNIQUES

A transcriptional sketch of a primary human breast cancer by 454 deep sequencing

(2009) Alessandro Guffanti et al.   BMC GENOMICS

Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy

(2009) J Dunn et al.   BRITISH JOURNAL OF CANCER

Clinical practice patterns and cost effectiveness of human epidermal growth receptor 2 testing strategies in breast cancer patients

(2009) Kathryn A. Phillips et al.   CANCER

Toward molecularly selected chemotherapy for advanced gastric cancer: State of the art and future perspectives

(2009) Mario Scartozzi et al.   CANCER TREATMENT REVIEWS

Circulating tumor cells (CTCs): Detection methods and their clinical relevance in breast cancer

(2009) Bianca Mostert et al.   CANCER TREATMENT REVIEWS

Novel Designs and End Points for Phase II Clinical Trials

(2009) A. A. Adjei et al.   CLINICAL CANCER RESEARCH

MicroRNAs: Novel Biomarkers for Human Cancer

(2009) C. L. Bartels et al.   CLINICAL CHEMISTRY

Critical review of microarray-based prognostic tests and trials in breast cancer

(2009) Serge Koscielny   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Comparison of accuracy of diagnostic modalities for evaluation of breast cancer with review of literature

(2009) Mulazim Hussain Bukhari et al.   DIAGNOSTIC CYTOPATHOLOGY

Breast cancer biomarkers and HER2 testing after 10 years of anti-HER2 therapy

(2009) J.S. Ross   DRUG NEWS & PERSPECTIVES

Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review

(2009) Glenn E Palomaki et al.   GENETICS IN MEDICINE

Gene signatures of pulmonary metastases of renal cell carcinoma reflect the disease-free interval and the number of metastases per patient

(2009) Daniela Wuttig et al.   INTERNATIONAL JOURNAL OF CANCER

Implementation of a novel microarray-based diagnostic test for cancer of unknown primary

(2009) Ryan K. van Laar et al.   INTERNATIONAL JOURNAL OF CANCER

Biomarkers for Response to Neoadjuvant Chemoradiation for Rectal Cancer

(2009) Jeffrey G. Kuremsky et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Long-Term Survival of Patients With Glioblastoma Treated With Radiotherapy and Lomustine Plus Temozolomide

(2009) Martin Glas et al.   JOURNAL OF CLINICAL ONCOLOGY

Aberrant DNA methylation in skin diseases

(2009) Yaping Li et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Monitoring Predominantly Cytostatic Treatment Response with 18F-FDG PET

(2009) K. B. Contractor et al.   JOURNAL OF NUCLEAR MEDICINE

DNA Microarray Expression Profiling of Bladder Cancer Allows Identification of Noninvasive Diagnostic Markers

(2009) Lourdes Mengual et al.   JOURNAL OF UROLOGY

Personalized Prediction of Tumor Response and Cancer Progression on Prostate Needle Biopsy

(2009) Michael J. Donovan et al.   JOURNAL OF UROLOGY

Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial

(2009) Ronald P DeMatteo et al.   LANCET

Exonic expression profiling of breast cancer and benign lesions: a retrospective analysis

(2009) Fabrice André et al.   LANCET ONCOLOGY

Molecular predictive and prognostic markers in non-small-cell lung cancer

(2009) Linda E Coate et al.   LANCET ONCOLOGY

A Genomic Strategy to Elucidate Modules of Oncogenic Pathway Signaling Networks

(2009) Jeffrey T. Chang et al.   MOLECULAR CELL

Key protein-design papers challenged

(2009) Erika Check Hayden   NATURE

Personalized cancer therapy gets closer

(2009) Erika Check Hayden   NATURE

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

(2009) Arun Sreekumar et al.   NATURE

Targeted capture and massively parallel sequencing of 12 human exomes

(2009) Sarah B. Ng et al.   NATURE

Virtual terminator nucleotides for next-generation DNA sequencing

(2009) Jayson Bowers et al.   NATURE METHODS

mRNA-Seq whole-transcriptome analysis of a single cell

(2009) Fuchou Tang et al.   NATURE METHODS

Programming the detection limits of biosensors through controlled nanostructuring

(2009) Leyla Soleymani et al.   Nature Nanotechnology

Next generation oncology drug development: opportunities and challenges

(2009) Martin E. Gutierrez et al.   Nature Reviews Clinical Oncology

New insights into the aetiology of colorectal cancer from genome-wide association studies

(2009) Albert Tenesa et al.   NATURE REVIEWS GENETICS

Challenges of translating genetic tests into clinical and public health practice

(2009) Wolf H. Rogowski et al.   NATURE REVIEWS GENETICS

Gene-Expression Signatures in Breast Cancer

(2009) Christos Sotiriou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Screening for Prostate Cancer — The Controversy That Refuses to Die

(2009) Michael J. Barry   NEW ENGLAND JOURNAL OF MEDICINE

Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

(2009) Eric Van Cutsem et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

(2009) Sohrab P. Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

Progress in the study of genetic disease: bringing new light to complex problems

(2009) A. Shelling   POSTGRADUATE MEDICAL JOURNAL

Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell

(2009) G. Sotiropoulou et al.   RNA

Epigenetic mechanisms in glioblastoma multiforme

(2009) Raman P. Nagarajan et al.   SEMINARS IN CANCER BIOLOGY

Epigenetic alterations in the breast: Implications for breast cancer detection, prognosis and treatment

(2009) Amy M. Dworkin et al.   SEMINARS IN CANCER BIOLOGY

Genomic Biomarkers for Molecular Imaging: Predicting the Future

(2009) Mathew L. Thakur   SEMINARS IN NUCLEAR MEDICINE

Molecular imaging in clinical trials

(2009) Debra Josephs et al.   Targeted Oncology

Genomic medicine: considerations for health professionals and the public

(2009) Denise Avard et al.   Genome Medicine

Reduced expression of a gene proliferation signature is associated with enhanced malignancy in colon cancer

(2008) A Anjomshoaa et al.   BRITISH JOURNAL OF CANCER

An E2F1-Dependent Gene Expression Program that Determines the Balance between Proliferation and Cell Death

(2008) Timothy C. Hallstrom et al.   CANCER CELL

Role of ING4 in human melanoma cell migration, invasion and patient survival

(2008) Jun Li et al.   CARCINOGENESIS

Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

(2008) Stephen Kalscheuer et al.   CARCINOGENESIS

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

(2008) Xi Chen et al.   CELL RESEARCH

HER3 Is a Determinant for Poor Prognosis in Melanoma

(2008) M. Reschke et al.   CLINICAL CANCER RESEARCH

Molecular markers detecting circulating melanoma cells by reverse transcription polymerase chain reaction: methodological pitfalls and clinical relevance

(2008) Adrianos Nezos et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

The Role of Molecular Imaging in Drug Discovery and Development

(2008) RJ Hargreaves   CLINICAL PHARMACOLOGY & THERAPEUTICS

Prognostic versus predictive value of biomarkers in oncology

(2008) C.N.A.M. Oldenhuis et al.   EUROPEAN JOURNAL OF CANCER

Trial Assessing Individualized Options for Treatment for breast cancer: the TAILORx trial

(2008) Jo Anne Zujewski et al.   Future Oncology

Microarray-based Gene Expression Profiling as a Clinical Tool for Breast Cancer Management: Are We There Yet?

(2008) Felipe Correa Geyer et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Delivery of Genomic Medicine for Common Chronic Adult Diseases

(2008) Maren T. Scheuner et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Gene Expression Signatures, Clinicopathological Features, and Individualized Therapy in Breast Cancer

(2008) Chaitanya R. Acharya   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Translational integrity and continuity: Personalized biomedical data integration

(2008) Xiaoming Wang et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Prognostic Utility of the 21-Gene Assay in Hormone Receptor–Positive Operable Breast Cancer Compared With Classical Clinicopathologic Features

(2008) Lori J. Goldstein et al.   JOURNAL OF CLINICAL ONCOLOGY

Role ofKRASandEGFRAs Biomarkers of Response to Erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21

(2008) Chang-Qi Zhu et al.   JOURNAL OF CLINICAL ONCOLOGY

Clinical Application of the 70-Gene Profile: The MINDACT Trial

(2008) Fatima Cardoso et al.   JOURNAL OF CLINICAL ONCOLOGY

Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer

(2008) Rafael G. Amado et al.   JOURNAL OF CLINICAL ONCOLOGY

Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer

(2008) Carsten Bokemeyer et al.   JOURNAL OF CLINICAL ONCOLOGY

Non-protein coding RNA biomarkers and differential expression in cancers: a review

(2008) Massimo Mallardo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Quantitative RT-PCR Detection of Colorectal Tumor Cells in Peripheral Blood—A Systematic Review

(2008) Gregory Sergeant et al.   JOURNAL OF SURGICAL RESEARCH

Diagnostic and Prognostic Molecular Markers in Renal Cell Carcinoma

(2008) Hari S.G.R. Tunuguntla et al.   JOURNAL OF UROLOGY

Translating insights from the cancer genome into clinical practice

(2008) Lynda Chin et al.   NATURE

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

(2008) Timothy J. Ley et al.   NATURE

Regulators weigh risks of consumer genetic tests

(2008) Charles Schmidt   NATURE BIOTECHNOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

The beginning of the end for microarrays?

(2008) Jay Shendure   NATURE METHODS

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE

Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer

(2008) Liqiang Xi et al.   NUCLEIC ACIDS RESEARCH

Commercialized Multigene Predictors of Clinical Outcome for Breast Cancer

(2008) J. S. Ross et al.   ONCOLOGIST

Age-Specific Differences in Oncogenic Pathway Deregulation Seen in Human Breast Tumors

(2008) Carey K. Anders et al.   PLoS One

An Integrated Approach to the Prediction of Chemotherapeutic Response in Patients with Breast Cancer

(2008) Kelly H. Salter et al.   PLoS One

A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities

(2008) K. S. Garman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated microfluidic bioprocessor for single-cell gene expression analysis

(2008) N. M. Toriello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PUBLIC HEALTH: A Case Study of Personalized Medicine

(2008) S. H. Katsanis et al.   SCIENCE

Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma

(2008) Tim F Cloughesy et al.   PLOS MEDICINE