Journal
ONCOIMMUNOLOGY
Volume 4, Issue 1, Pages -Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/21624011.2014.955683
Keywords
antigen-specific T-cells; intracellular cytokine staining; Melan-A; MAGE-A3; NY-ESO-1; survivin
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The melanoma-associated antigens Melan-A and NY-ESO-1 stimulate different T-cell responses in late-stage melanoma patients. Either CD4(+) or CD8(+) T-cell reactivity against NY-ESO-1 was associated with better prognosis, but for Melan-A, only CD8(+) but not CD4(+) T-cell responses were associated with longer survival.
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