Cervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretion

Tumor-induced perturbations of cytokines and immune cell networks

(2014) Brett Burkholder et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Tumoral RANKL activates astrocytes that promote glioma cell invasion through cytokine signaling

(2014) Jun-Kyum Kim et al.   CANCER LETTERS

What Are the Molecules Involved in Regulatory T-Cells Induction by Dendritic Cells in Cancer?

(2013) Rodrigo Nalio Ramos et al.   Clinical & Developmental Immunology

Multifunctional properties of RANKL/RANK in cell differentiation, proliferation and metastasis

(2013) Akiko Kukita et al.   Future Oncology

Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL

(2013) N C Walsh et al.   GENES AND IMMUNITY

Increased expression of programmed death (PD)-1 and its ligand PD-L1 correlates with impaired cell-mediated immunity in high-risk human papillomavirus-related cervical intraepithelial neoplasia

(2013) Wen Yang et al.   IMMUNOLOGY

Inactivation of tumor-specific CD8+ CTLs by tumor-infiltrating tolerogenic dendritic cells

(2013) Hirotomo Harimoto et al.   IMMUNOLOGY AND CELL BIOLOGY

Altered Immunity and Dendritic Cell Activity in the Periphery of Mice after Long-Term Engraftment with Bone Marrow from Ultraviolet-Irradiated Mice

(2013) R. L. X. Ng et al.   JOURNAL OF IMMUNOLOGY

Tumour Immunomodulation: Mucins in Resistance to Initiation and Maturation of Immune Response Against Tumours

(2013) A. AnandKumar et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Progesterone/RANKL Is a Major Regulatory Axis in the Human Breast

(2013) T. Tanos et al.   Science Translational Medicine

RANKL downregulates cell surface CXCR6 expression through JAK2/STAT3 signaling pathway during osteoclastogenesis

(2012) Changhong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Marginating Dendritic Cells of the Tumor Microenvironment Cross-Present Tumor Antigens and Stably Engage Tumor-Specific T Cells

(2012) John J. Engelhardt et al.   CANCER CELL

Immune suppression in the tumor microenvironment: a role for dendritic cell-mediated tolerization of T cells

(2012) Arthur A. Hurwitz et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Induction of antigen-specific human T suppressor cells by membrane and soluble ILT3

(2012) George Vlad et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Production of large numbers of plasmacytoid dendritic cells with functional activities from CD34+ hematopoietic progenitor cells: Use of interleukin-3

(2012) Stéphanie Demoulin et al.   EXPERIMENTAL HEMATOLOGY

Functional Tumor Infiltrating TH1 and TH2 Effectors in Large Early-Stage Cervical Cancer Are Suppressed by Regulatory T Cells

(2012) Sreenivas Adurthi et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Homotypic RANK signaling differentially regulates proliferation, motility and cell survival in osteosarcoma and mammary epithelial cells

(2012) Alexander G. Beristain et al.   JOURNAL OF CELL SCIENCE

Tumor microenvironment converts plasmacytoid dendritic cells into immunosuppressive/tolerogenic cells: insight into the molecular mechanisms

(2012) S. Demoulin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TRAIL and osteoprotegerin (OPG) expression in bladder urothelial carcinoma: correlation with clinicopathological parameters and prognosis

(2012) Georgia Levidou et al.   PATHOLOGY

Soluble Rank Ligand Produced by Myeloma Cells Causes Generalised Bone Loss in Multiple Myeloma

(2012) Clive Henry Buckle et al.   PLoS One

Dendritic cell subsets and immunological milieu in inflammatory human papilloma virus-related skin lesions

(2011) Yumi Nakayama et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The Role of RANK-Ligand Inhibition in Cancer: The Story of Denosumab

(2011) D. Castellano et al.   ONCOLOGIST

Cigarette smoking habit does not reduce the benefit from first line trastuzumab-based treatment in advanced breast cancer patients

(2011) Daniele Santini   ONCOLOGY REPORTS

Langerhans cells are precommitted to immune tolerance induction

(2011) E. Shklovskaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis

(2011) Daniel Schramek et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The L1 major capsid protein of HPV16 differentially modulates APC trafficking according to the vaccination or natural infection context

(2010) Ludivine Herman et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin

(2010) Nikolaus Romani et al.   IMMUNOLOGICAL REVIEWS

RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis

(2010) Eva Gonzalez-Suarez et al.   NATURE

Tumor-Expressed B7-H1 and B7-DC in Relation to PD-1+ T-Cell Infiltration and Survival of Patients with Cervical Carcinoma

(2009) R. Karim et al.   CLINICAL CANCER RESEARCH

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

The Induction of APC with a Distinct Tolerogenic Phenotype via Contact-Dependent STAT3 Activation

(2009) Devorah Gur-Wahnon et al.   PLoS One

Epithelial metaplasia: adult stem cell reprogramming and (pre)neoplastic transformation mediated by inflammation?

(2009) Michael Herfs et al.   TRENDS IN MOLECULAR MEDICINE

High expression of PGE2 enzymatic pathways in cervical (pre)neoplastic lesions and functional consequences for antigen-presenting cells

(2008) Michaël Herfs et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Increased migration of Langerhans cells in response to HPV16 E6 and E7 oncogene silencing: role of CCL20

(2008) Jean-Hubert Caberg et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Receptor activator of NF-κB Ligand (RANKL) expression is associated with epithelial to mesenchymal transition in human prostate cancer cells

(2008) Valerie A Odero-Marah et al.   CELL RESEARCH

Tumor-induced modulation of dendritic cell function

(2007) E GOTTFRIED et al.   CYTOKINE & GROWTH FACTOR REVIEWS