Myeloid cells in the tumor microenvironment: Role of adenosine

Tumor-associated macrophages as an emerging target against tumors: Creating a new path from bench to bedside

(2015) Masahisa Jinushi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Something in the Air: Hyperoxic Conditioning of the Tumor Microenvironment for Enhanced Immunotherapy

(2015) Robert D. Leone et al.   CANCER CELL

Tissue-resident macrophages: then and now

(2015) Luke C. Davies et al.   IMMUNOLOGY

Involvement of purinergic system in the release of cytokines by macrophages exposed to glioma-conditioned medium

(2015) Letícia Scussel Bergamin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-Infiltrating Dendritic Cells in Cancer Pathogenesis

(2015) Jo Marie Tran Janco et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Derived Suppressor Cells and Therapeutic Strategies in Cancer

(2015) Hiroshi Katoh et al.   MEDIATORS OF INFLAMMATION

Mast cells as targets for immunotherapy of solid tumors

(2015) Sharon A. Oldford et al.   MOLECULAR IMMUNOLOGY

Combination cancer immunotherapy and new immunomodulatory targets

(2015) Kathleen M. Mahoney et al.   NATURE REVIEWS DRUG DISCOVERY

The Evolving Role of Immune Checkpoint Inhibitors in Cancer Treatment

(2015) G. K. Pennock et al.   ONCOLOGIST

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

(2015) L Baron et al.   Cell Death & Disease

Myeloid-derived suppressor cells contribute to A2B adenosine receptor-induced VEGF production and angiogenesis in a mouse melanoma model

(2015) Claudia Sorrentino et al.   Oncotarget

Reprogramming the tumor microenvironment: tumor-induced immunosuppressive factors paralyze T cells

(2015) Annie A Wu et al.   OncoImmunology

Blockade of A2b Adenosine Receptor Reduces Tumor Growth and Immune Suppression Mediated by Myeloid-Derived Suppressor Cells in a Mouse Model of Melanoma

(2015) Raffaella Iannone et al.   NEOPLASIA

Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety

(2014) Gabriel S. Chiu et al.   BRAIN BEHAVIOR AND IMMUNITY

Myeloid Expression of Adenosine A2A Receptor Suppresses T and NK Cell Responses in the Solid Tumor Microenvironment

(2014) C. Cekic et al.   CANCER RESEARCH

Plasticity of Macrophage Function during Tumor Progression: Regulation by Distinct Molecular Mechanisms

(2014) S. K. Biswas et al.   JOURNAL OF IMMUNOLOGY

Role of TGF-β Signaling in Generation of CD39+CD73+Myeloid Cells in Tumors

(2014) Sergey V. Ryzhov et al.   JOURNAL OF IMMUNOLOGY

Targeting Cancer-Derived Adenosine:New Therapeutic Approaches

(2014) A. Young et al.   Cancer Discovery

Targeting the adenosine A2b receptor in the tumor microenvironment overcomes local immunosuppression by myeloid-derived suppressor cells

(2014) Silvana Morello et al.   OncoImmunology

Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment

(2014) Theerawut Chanmee et al.   Cancers

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells

(2013) Yuting Ma et al.   IMMUNITY

Hypoxia-induced and A2A adenosine receptor-independent T-cell suppression is short lived and easily reversible

(2013) Akio Ohta et al.   INTERNATIONAL IMMUNOLOGY

Cancer immunotherapy

(2013) Lauren Gravitz   NATURE

Blockade of A2Areceptors potently suppresses the metastasis of CD73+tumors

(2013) Paul A. Beavis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

(2013) C. J. Desmet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

Dendritic Cells in the Cancer Microenvironment

(2013) Yang Ma et al.   Journal of Cancer

Regulation of Macrophage Function by Adenosine

(2012) György Haskó et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

(2012) M. A. Swartz et al.   CANCER RESEARCH

Adenosine and cAMP signalling skew human dendritic cell differentiation towards a tolerogenic phenotype with defective CD8+T-cell priming capacity

(2012) John Challier et al.   IMMUNOLOGY

The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

(2012) Dennis Lindau et al.   IMMUNOLOGY

Comment on "Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells"

(2012) I. Shevchenko et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Mast Cells Critically Augment Myeloid-Derived Suppressor Cell Activity

(2012) S. J. Saleem et al.   JOURNAL OF IMMUNOLOGY

Myeloid-derived Suppressor Cells in Cancer Patients

(2012) Alberto J. Montero et al.   JOURNAL OF IMMUNOTHERAPY

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

Ecto-5′-Nucleotidase (CD73) Decreases Mortality and Organ Injury in Sepsis

(2011) György Haskó et al.   JOURNAL OF IMMUNOLOGY

Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells

(2011) S. Ryzhov et al.   JOURNAL OF IMMUNOLOGY

Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors

(2011) C. Cekic et al.   JOURNAL OF IMMUNOLOGY

IL-4 Amplifies the Pro-Inflammatory Effect of Adenosine in Human Mast Cells by Changing Expression Levels of Adenosine Receptors

(2011) Xiaoyang Hua et al.   PLoS One

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Mast Cells Mobilize Myeloid-Derived Suppressor Cells and Treg Cells in Tumor Microenvironment via IL-17 Pathway in Murine Hepatocarcinoma Model

(2010) Zhuoshun Yang et al.   PLoS One

Dendritic cells integrate signals from the tumor microenvironment to modulate immunity and tumor growth

(2009) Albert Lin et al.   IMMUNOLOGY LETTERS

Adenosine: roles of different receptor subtypes in mediating histamine release from human and rodent mast cells

(2009) K. H. Yip et al.   INFLAMMATION RESEARCH

The A2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells

(2009) J. M. Wilson et al.   JOURNAL OF IMMUNOLOGY

T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response

(2009) Michail V. Sitkovsky   TRENDS IN IMMUNOLOGY

SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment

(2008) B. Huang et al.   BLOOD

Adenosine receptors in regulation of dendritic cell differentiation and function

(2008) S. V. Novitskiy et al.   BLOOD

Modulation of murine dendritic cell function by adenine nucleotides and adenosine: Involvement of the A2B receptor

(2008) Abduelhakem Ben Addi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells

(2008) Ilaria Marigo et al.   IMMUNOLOGICAL REVIEWS

Effects of IL-4 and IL-13 on adenosine receptor expression and responsiveness of the human mast cell line 1

(2008) Mieke Versluis et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer

(2008) Yoshiki Mizukami et al.   INTERNATIONAL JOURNAL OF CANCER

Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells

(2008) Xiaoyang Hua et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

(2008) Naoki Umemura et al.   JOURNAL OF LEUKOCYTE BIOLOGY