Chemical synthesis of proteins using hydrazide intermediates

Blocking of the PD-1/PD-L1 Interaction by aD-Peptide Antagonist for Cancer Immunotherapy

(2015) Hao-Nan Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Efficient One-Pot Four-Segment Condensation Method for Protein Chemical Synthesis

(2015) Shan Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fast and catalyst-free hydrazone ligation via ortho-halo-substituted benzaldehydes for protein C-terminal labeling at neutral pH

(2015) Yang Xu et al.   CHEMICAL COMMUNICATIONS

Efficient generation of peptide hydrazides via direct hydrazinolysis of Peptidyl-Wang-TentaGel resins

(2015) Claudia Bello et al.   JOURNAL OF PEPTIDE SCIENCE

Chemical synthesis of crystalline proteins

(2015) Yichao Huang et al.   Science China-Chemistry

Chemical synthesis of a two-photon-activatable chemokine and photon-guided lymphocyte migration in vivo

(2015) Xin Chen et al.   Nature Communications

Development of a Chemical Methodology for the Preparation of Peptide Thioesters Applicable to Naturally Occurring Peptides Using a Sequential Quadruple Acyl Transfer System

(2015) Yusuke Tsuda et al.   ChemistryOpen

Synthesis of Highly-strained Cyclic Tetrapeptides via Peptide Hydrazide Based Ligation

(2015) Han Liu et al.   ACTA CHIMICA SINICA

Peptideo-Aminoanilides as Crypto-Thioesters for Protein Chemical Synthesis

(2014) Jia-Xing Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Semisynthesis of Biologically Active Glycoforms of the Human Cytokine Interleukin 6

(2014) Andreas Reif et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Irreversible Site-Specific Hydrazinolysis of Proteins by Use of Sortase

(2014) Yi-Ming Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-pot hydrazide-based native chemical ligation for efficient chemical synthesis and structure determination of toxin Mambalgin-1

(2014) Man Pan et al.   CHEMICAL COMMUNICATIONS

Expedient Total Synthesis of Small to Medium-Sized Membrane Proteins via Fmoc Chemistry

(2014) Ji-Shen Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-pot native chemical ligation of peptide hydrazides enables total synthesis of modified histones

(2014) Jiabin Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Photolabile Linker for the Solid-Phase Synthesis of Peptide Hydrazides and Heterocycles

(2014) Katrine Qvortrup et al.   ORGANIC LETTERS

Synthesis and folding of a mirror-image enzyme reveals ambidextrous chaperone activity

(2014) M. T. Weinstock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Facile synthesis of C-terminal peptide hydrazide and thioester of NY-ESO-1 (A39-A68) from an Fmoc-hydrazine 2-chlorotrityl chloride resin

(2014) Yi-Chao Huang et al.   TETRAHEDRON

Development of New Thioester Equivalents for Protein Chemical Synthesis

(2013) Ji-Shen Zheng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cysteine Promoted C-Terminal Hydrazinolysis of Native Peptides and Proteins

(2013) Anna L. Adams et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Convergent Chemical Synthesis of Histone H2B Protein for the Site-Specific Ubiquitination at Lys34

(2013) Peter Siman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical synthesis of proteins using peptide hydrazides as thioester surrogates

(2013) Ji-Shen Zheng et al.   Nature Protocols

A Thioethylalkylamido (TEA) Thioester Surrogate in the Synthesis of a Cyclic Peptide via a Tandem Acyl Shift

(2013) Misako Taichi et al.   ORGANIC LETTERS

H3R42me2a is a histone modification with positive transcriptional effects

(2013) F. Casadio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligation of Expressed Protein α-Hydrazides via Genetic Incorporation of an α-Hydroxy Acid

(2012) Yi-Ming Li et al.   ACS Chemical Biology

Convergent Chemical Synthesis of Proteins by Ligation of Peptide Hydrazides

(2012) Ge-Min Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Cyclic Peptides and Cyclic Proteins via Ligation of Peptide Hydrazides

(2012) Ji-Shen Zheng et al.   CHEMBIOCHEM

Sequential native peptide ligation strategies for total chemical protein synthesis

(2012) Laurent Raibaut et al.   CHEMICAL SOCIETY REVIEWS

A One-Pot Three-Segment Ligation Strategy for Protein Chemical Synthesis

(2011) Nathalie Ollivier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Chemical Synthesis by Ligation of Peptide Hydrazides

(2011) Ge-Min Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recombinant Protein Hydrazides: Application to Site-Specific Protein PEGylation

(2011) Jennifer Thom et al.   BIOCONJUGATE CHEMISTRY

N-Sulfanylethylanilide Peptide as a Crypto-Thioester Peptide

(2011) Kohei Sato et al.   CHEMBIOCHEM

Peptide Coupling Reagents, More than a Letter Soup

(2011) Ayman El-Faham et al.   CHEMICAL REVIEWS

9-Fluorenylmethoxycarbonyl-Based Solid-Phase Synthesis of Peptide α-Thioesters

(2010) Franziska Mende et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequence-Specific Ni(II)-Dependent Peptide Bond Hydrolysis for Protein Engineering. Combinatorial Library Determination of Optimal Sequences

(2010) Artur Krȩżel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bis(2-sulfanylethyl)amino Native Peptide Ligation

(2010) Nathalie Ollivier et al.   ORGANIC LETTERS

PeptidylN,N-Bis(2-mercaptoethyl)-amides as Thioester Precursors for Native Chemical Ligation†

(2010) Wen Hou et al.   ORGANIC LETTERS

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Useful Tools for Biomolecule Isolation, Detection, and Identification: Acylhydrazone-Based Cleavable Linkers

(2009) Ki Duk Park et al.   CHEMISTRY & BIOLOGY

Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology

(2009) Justin M. Chalker et al.   Chemistry-An Asian Journal

Expressed Protein Ligation (EPL) in the Study of Signal Transduction, Ion Conduction, And Chromatin Biology

(2008) Robert R. Flavell et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chemoselective Ligation and Modification Strategies for Peptides and Proteins

(2008) Christian P. R. Hackenberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total chemical synthesis of proteins

(2008) Stephen B. H. Kent   CHEMICAL SOCIETY REVIEWS

Switch Peptide via Staudinger Reaction

(2008) Natalia Nepomniaschiy et al.   ORGANIC LETTERS

Head-to-Tail Cyclized Cystine-Knot Peptides by a Combined Recombinant and Chemical Route of Synthesis

(2007) Olga Avrutina et al.   CHEMBIOCHEM