Multiple receptor tyrosine kinases promote the in vitro phenotype of metastatic human osteosarcoma cell lines

Osteosarcoma

(2016) Patrick J. Messerschmitt et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors

(2012) Y. Bai et al.   CANCER RESEARCH

E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion

(2011) Hilary Glen et al.   BMC CANCER

A comprehensive candidate gene approach identifies genetic variation associated with osteosarcoma

(2011) Lisa Mirabello et al.   BMC CANCER

The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma

(2011) Alvarez Hector et al.   CANCER BIOLOGY & THERAPY

Parathyroid hormone affects the fibroblast growth factor-proteoglycan signaling axis to regulate osteosarcoma cell migration

(2011) Georgios A. Datsis et al.   FEBS Journal

R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

(2010) S. J. Holland et al.   CANCER RESEARCH

Pharmacokinetically Guided Phase 1 Trial of the IGF-1 Receptor Antagonist RG1507 in Children with Recurrent or Refractory Solid Tumors

(2010) R. Bagatell et al.   CLINICAL CANCER RESEARCH

De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway

(2010) Raphaela Fritsche-Guenther et al.   HISTOPATHOLOGY

RET-Mediated Cell Adhesion and Migration Require Multiple Integrin Subunits

(2010) Jessica G. Cockburn et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Paracrine Regulation of Pancreatic Cancer Cell Invasion by Peripheral Nerves

(2010) Ziv Gil et al.   JNCI-Journal of the National Cancer Institute

An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors

(2010) Tingsheng Peng et al.   LABORATORY INVESTIGATION

Artemin-Stimulated Progression of Human Non-Small Cell Lung Carcinoma Is Mediated by BCL2

(2010) J.-Z. Tang et al.   MOLECULAR CANCER THERAPEUTICS

Combination of Two Insulin-Like Growth Factor-I Receptor Inhibitory Antibodies Targeting Distinct Epitopes Leads to an Enhanced Antitumor Response

(2010) J. Dong et al.   MOLECULAR CANCER THERAPEUTICS

A Fully Human Insulin-Like Growth Factor-I Receptor Antibody SCH 717454 (Robatumumab) Has Antitumor Activity as a Single Agent and in Combination with Cytotoxics in Pediatric Tumor Xenografts

(2010) Y. Wang et al.   MOLECULAR CANCER THERAPEUTICS

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Initial testing (stage 1) of AZD6244 (ARRY-142886) by the pediatric preclinical testing program

(2010) E. Anders Kolb et al.   PEDIATRIC BLOOD & CANCER

Functional genome screen for therapeutic targets of osteosarcoma

(2009) Umio Yamaguchi et al.   CANCER SCIENCE

Identification of interactive networks of gene expression associated with osteosarcoma oncogenesis by integrated molecular profiling

(2009) Bekim Sadikovic et al.   HUMAN MOLECULAR GENETICS

Validation of immature adipogenic status and identification of prognostic biomarkers in myxoid liposarcoma using tissue microarrays

(2009) Hongwei Cheng et al.   HUMAN PATHOLOGY

Lentivirus-mediated RNAi knockdown of insulin-like growth factor-1 receptor inhibits growth, reduces invasion, and enhances radiosensitivity in human osteosarcoma cells

(2009) Yin-He Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Development of IGF-IR inhibitors in pediatric sarcomas

(2009) E. Anders Kolb et al.   Current Oncology Reports

Specific Tyrosine Kinase Inhibitors Regulate Human Osteosarcoma Cells In vitro

(2008) Patrick J. Messerschmitt et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Osteosarcoma: The Addition of Muramyl Tripeptide to Chemotherapy Improves Overall Survival—A Report From the Children's Oncology Group

(2008) Paul A. Meyers et al.   JOURNAL OF CLINICAL ONCOLOGY

Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program

(2008) E. Anders Kolb et al.   PEDIATRIC BLOOD & CANCER

Phosphoproteomics, oncogenic signaling and cancer research

(2008) Poh-Kuan Chong et al.   PROTEOMICS