Article
Medicine, General & Internal
Luis D. Pacheco, Rebecca G. Clifton, George R. Saade, Steven J. Weiner, Samuel Parry, John M. Thorp Jr, Monica Longo, Ashley Salazar, Wendy Dalton, Alan T. N. Tita, Cynthia Gyamfi-Bannerman, Suneet P. Chauhan, Torri D. Metz, Kara Rood, Dwight J. Rouse, Jennifer L. Bailit, William A. Grobman, Hyagriv N. Simhan, George A. Macones
Summary: Prophylactic use of tranexamic acid during cesarean delivery did not lead to a significantly lower risk of maternal death or blood transfusion than placebo.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Biotechnology & Applied Microbiology
Xinyang Li, Moli Yin, Hongmei Wang, Shengbao Duan, Huiyan Wang, Yong Li, Tiemei Liu
Summary: The study found that the hydrogel fluoroimmunoassay can accurately measure fluorescence intensity by flow cytometry, differentiate fetal hemoglobin from adult hemoglobin, and thus provide quantitative prenatal diagnosis of fetal hemoglobin to address the immunological reaction caused by incompatibility between fetal and maternal blood types.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Obstetrics & Gynecology
Maria Gaia Dodaro, Anna Seidenari, Ignazio R. Marino, Vincenzo Berghella, Federica Bellussi
Summary: In 35 cases of brain death during pregnancy at an average gestational age of 20 weeks, maternal somatic support aimed at maximizing perinatal outcome lasted for about 7 weeks, with 77% of neonates being born alive and 85% of these infants having a normal outcome at 20 months of life. The data of this study will be helpful in counseling families and practitioners faced with such rare and complex cases.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Review
Obstetrics & Gynecology
Yasuko Sano, Michi Kasai, Satoru Shinoda, Etsuko Miyagi, Shigeru Aoki
Summary: This study aimed to investigate possible factors indicating the need for early blood transfusion and the applicability of the Japanese scoring system for PPH in patients with PA-IUFD. The results showed that indicators such as fibrinogen levels, platelet count, D-dimer levels, FDP, and heart rate on admission may suggest the need for blood transfusion in patients with PA-IUFD.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Health Care Sciences & Services
Chiharu Suemitsu, Megumi Fudaba, Kohei Kitada, Yasushi Kurihara, Mie Tahara, Akihiro Hamuro, Takuya Misugi, Akemi Nakano, Masayasu Koyama, Daisuke Tachibana
Summary: The aims of this study were to evaluate coagulation and fibrinolytic features using TEG6s (R) in different pregnancy stages and in cases with postpartum hemorrhage caused by uterine atony or deep venous thrombosis and/or pulmonary embolism. Significant changes in clot formation parameters and maintenance of low fibrinolytic parameter LY30 were observed after placental delivery and in cases with uterine atony. The effectiveness of heparin showed strong correlation with activated partial thromboplastin time.
Review
Immunology
Gabrielle Rizzuto, Adrian Erlebacher
Summary: The paradox of fetomaternal tolerance has been a mystery to immunologists and reproductive biologists for nearly 70 years. By synthesizing older observations with recent studies, this article discusses the decision between tolerance or immunity to fetoplacental antigens based on their origin and glycosylation, highlighting the different responses observed for trophoblast-derived antigens compared to fetal blood cell-derived antigens.
JOURNAL OF EXPERIMENTAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Stephen Contag, Rahel Nardos, Irina A. Buhimschi, Jennifer Almanza
Summary: A study in Minnesota found that Somali women have longer gestational ages at delivery compared to other ethnic groups, resulting in higher risks for stillbirth and neonatal death rates. However, at 42 weeks, Somali neonatal mortality decreased and was comparable to that of the U.S. born White population, and lower than that of other minorities.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Cesaltina Soares Muniz, Beatriz Frota Dias, Paula Vitoria Pereira Motoyama, Camila Timbo Catunda Almeida, Francisco Edson de Lucena Feitosa, Edward Araujo Junior, Julio Augusto Gurgel Alves
Summary: Early-onset FGR is more likely to be associated with hypertensive disorders and placental vascular insufficiency, leading to higher rates of adverse perinatal outcomes compared to late-onset FGR.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Silvia Santos Monteiro, Liliana Fonseca, Tiago S. Santos, Miguel Saraiva, Teresa Pereira, Joana Vilaverde, Fernando Pichel, Clara Pinto, Jorge Dores
Summary: This study aimed to compare fetomaternal outcomes in pregnant women with gestational diabetes mellitus (GDM) between twin and singleton pregnancies, as well as between GDM and non-GDM twin pregnancies. The results showed that twin pregnancies in GDM women had higher rates of preeclampsia, cesarean delivery, and neonatal morbidity compared to singleton pregnancies. However, there were no significant differences in fetomaternal morbidity parameters between GDM and non-GDM twin pregnancies. GDM appeared to be protective against the occurrence of small-for-gestational-age (SGA) neonates in twin pregnancies.
ACTA DIABETOLOGICA
(2022)
Article
Pathology
Precious Ann Fortes, Esteban D. Gnass, Janet Baez, Banafsheh Bayati, Zhen Mei, Andrea M. McGonigle, Alyssa Ziman, Dawn C. Ward
Summary: This article reports a case of massive fetomaternal hemorrhage and the successful prevention of Rh(D) alloimmunization using IV RhIG, resulting in a subsequent healthy pregnancy.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
(2023)
Article
Obstetrics & Gynecology
Maria Fernanda Escobar, Maria Paula Echavarria, Hilda Vasquez, Daniela Nasner, Isabella Ramos, Maria Antonia Hincapie, Stephanie Pabon, Juan Pedro Kusanovic, Diana Marcela Martinez-Ruiz, Javier Andres Carvajal
Summary: This study aimed to evaluate the impact of a model based on telehealth and education on the quality indicators of maternal and perinatal care in two hospitals in the southwestern region of Colombia. The results showed that after implementing the model, there was a reduction in perinatal mortality by 29%, a decrease in the need for blood transfusion due to postpartum hemorrhage, and a decrease in the rate of eclampsia.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Public, Environmental & Occupational Health
Ellen O. Carlsen, Quaker Harmon, Maria C. Magnus, Helle M. Meltzer, Iris Erlund, Lars C. Stene, Siri E. Haberg, Allen J. Wilcox
Summary: This study found that among women without a history of diabetes, higher HbA1c levels at 18 weeks of pregnancy were associated with important perinatal outcomes, including birth weight, large-for-gestational age, preterm delivery, and preeclampsia.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Medicine, General & Internal
Chengtian Lv, Lichan Wu, Guangyuan Liao, Yuwen Huang, Jingyi Chen, Shuyi Jiang, Dunjin Chen, Yuanmei Gao
Summary: This retrospective study analyzed the medical record data of 154 patients with Pulmonary Hypertension (PH) and found significant differences in heart failure, premature delivery, Very-Low-Birth-Weight (VLBW) infants, and Small-for-Gestational-Age (SGA) infants among different severity groups. The risk of maternal mortality was significantly higher in the severe PH group compared to the mild-moderate group, highlighting the importance of pulmonary artery pressure screening before pregnancy, early advice on contraception, and multidisciplinary care.
Article
Obstetrics & Gynecology
Roopali Donepudi, Jean-Marie Jouannic, Emeline Maisonneuve, Nicolas Sananes, Celine Muller, Ma Sanchez-Duran, Francisca Molina, Pilar Carretero, Eugenia Antolin, Inmaculada Duyos, Isabella Fabietti, Asma Khalil, Conrado M. Coutinho, Haleh Sangi-Haghpeykar, Magdalena Sanz Cortes
Summary: This study compares different techniques for treating fetal anemia and finds that intravascular transfusion is the most commonly used technique, while other techniques are more likely to be used in cases with hydrops and lower starting hematocrit. However, both techniques have no impact on outcomes, suggesting that physician experience may be the most important factor influencing results.
FETAL DIAGNOSIS AND THERAPY
(2023)
Article
Obstetrics & Gynecology
Aminu Ado Wakili, Ashraf Aswat, Rebecca Timms, Leanne Beeson, Kristie-Marie Mammoliti, Adam Devall, Baba Maiyaki Musa, Taiwo Amole, Faisal Dankishiya, Arri Coomarasamy, Ioannis D. Gallos, Hadiza S. Galadanci
Summary: There is significant variation in postpartum hemorrhage rates and adverse maternal outcomes in Nigerian healthcare facilities, highlighting the need for further understanding of the underlying causes and challenges in order to implement tailored solutions to improve maternal outcomes.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Editorial Material
Obstetrics & Gynecology
Divya Gautam, Gillian A. Ryan, Fionnuala M. McAuliffe, Nikhil Purandare
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Helena C. Bartels, Jennifer M. Walsh, Clare O'Connor, Peter McParland, Stephen Carroll, Shane Higgins, Karen M. Mulligan, Paul Downey, David Brophy, Gabrielle Colleran, Claire Thompson, Tom Walsh, Donal J. O'Brien, Donal J. Brennan, Ruaidhri McVey, Fionnuala M. McAuliffe, Jennifer Donnelly, Siobhan M. Corcoran
Summary: The objective of this study was to evaluate fetal growth in pregnancies complicated by placenta accreta spectrum (PAS) and compare fetal growth between different ultrasound stages of PAS. The results showed that the diagnosis of PAS was not associated with fetal growth restriction.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Acoustics
B. D. O'Leary, L. Kelly, M. Fitzpatrick, D. P. Keane
Summary: This study aimed to examine the prevalence of internal anal sphincter (IAS) damage in women with Grade-3a or -3b obstetric anal sphincter injury (OASI) using endoanal ultrasonography. The results showed that 1 in 11 women with Grade-3a or -3b tear had evidence of IAS damage. IAS damage is associated with fecal incontinence in women and can significantly affect future delivery planning.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Bobby D. O'Leary, Alexandra McCreery, Aisling E. Redmond, Declan P. Keane
Summary: This study analyzed patient-reported outcomes of tension-free vaginal tapes (TVT) after 16-24 years. The results showed that TVT had high levels of satisfaction and cure up to 24 years after placement. Pain was uncommon and had low impact on quality of life, while symptoms of urgency were prevalent and may be related to age.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Review
Obstetrics & Gynecology
Elizabeth Tunney, Bobby O'Leary, Fergal Malone, Michael Geary
Summary: This study reviewed the literature on obstetric rectal buttonhole injuries and provided additional cases from the institution. The results showed variations in repair techniques, but most patients had no complications after surgery.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Environmental Sciences
Doireann Roche, Anthony Rafferty, Sinead Holden, Sarah Louise Killeen, Maria Kennelly, Fionnuala M. McAuliffe
Summary: This study aimed to examine the association between early pregnancy well-being and stage of behavior change during an antenatal lifestyle intervention. The results showed that both maternal well-being and the study group significantly influenced the positive stage of behavior change, highlighting the potential importance of well-being in promoting women's engagement in a healthy lifestyle.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Obstetrics & Gynecology
Bobby D. O'Leary, Declan P. Keane
Summary: This study aimed to determine the effect of the length of the second stage of labor on self-reported pelvic floor dysfunction. The results showed that a prolonged second stage of labor is associated with more self-reported bladder dysfunction at 3 months postnatal in primiparous women. This finding is important for women and healthcare providers.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Obstetrics & Gynecology
Clare M. Crowley, Niamh A. Lang, Bobby D. O'Leary, Michael P. Geary
Summary: This retrospective study examined trends in operative vaginal deliveries over a 15-year period and found a decline in the rate of operative vaginal delivery and an increase in the use of vacuum-assisted deliveries compared to forceps-assisted deliveries. Perineal trauma rates remained unchanged during the study period.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Bobby D. O'Leary, Declan P. Keane
Summary: Childbirth is a significant risk factor for pelvic floor disorders, and accurate assessments are needed for these symptoms. Online assessment tools may be valuable in the COVID-19 era. This study validated an online version of the Australian Pelvic Floor Questionnaire (APFQ) and found it to be valid for assessing pelvic floor disorders.
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2023)
Article
Multidisciplinary Sciences
Conor Feehily, Ian J. O'Neill, Calum J. Walsh, Rebecca L. Moore, Sarah Louise Killeen, Aisling A. Geraghty, Elaine M. Lawton, David Byrne, Rocio Sanchez-Gallardo, Sai Ravi Chandra Nori, Ida Busch Nielsen, Esther Wortmann, Elizabeth Matthews, Roisin O'Flaherty, Pauline M. Rudd, David Groeger, Fergus Shanahan, Radka Saldova, Fionnuala M. McAuliffe, Douwe Van Sinderen, Paul D. Cotter
Summary: The authors combine isolation and sequencing of bacteria from both mothers and infants to investigate microbial strain transfer, particularly in the genus Bifidobacterium. They reveal that strain transfer occurs in almost 50% of dyads, with factors such as vaginal birth and avoidance of intrapartum antibiotics being important. Dual approaches, combining cultivation and metagenomic sequencing, are necessary for a comprehensive understanding of this transfer process.
NATURE COMMUNICATIONS
(2023)
Editorial Material
Obstetrics & Gynecology
Long Nguyen-Hoang, Graeme N. Smith, Lina Bergman, Fionnuala M. McAuliffe, Liona C. Poon
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Microbiology
Cara A. Yelverton, Sarah Louise Killeen, Conor Feehily, Rebecca L. Moore, Shauna L. Callaghan, Aisling A. Geraghty, David F. Byrne, Calum J. Walsh, Elaine M. Lawton, Eileen F. Murphy, Douwe Van Sinderen, Paul D. Cotter, Fionnuala M. Mcauliffe
Summary: This study explored the relationships among maternal well-being during pregnancy, breastfeeding, and the infant gut microbiome. The results showed that maternal well-being during pregnancy was not associated with infant microbial diversity. However, exclusive breastfeeding at discharge from hospital was associated with infant microbial beta diversity, and any breastfeeding at 1 month postpartum was associated with infant microbial alpha diversity, observed species, and beta diversity. Exclusive breastfeeding at 1 month postpartum was also associated with infant alpha diversity and number of observed microbial species.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Health Care Sciences & Services
Sharleen L. O'Reilly, Rachel Laws, Helle Terkildsen Maindal, Helena Teede, Cheryce Harrison, Fionnuala M. McAuliffe, Aisling Geraghty, Cristina Campoy, Mercedes G. Bermudez, Laura Pirhonen, Christy Burden, Anna Davies, Ditte Hjorth Laursen, Timothy Skinner
Summary: This study aims to explore the feasibility and implementation of the B2B&Me intervention and investigate its effectiveness in women at risk of gestational diabetes.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Obstetrics & Gynecology
Rebecca L. Moore, Conor Feehily, Sarah Louise Killeen, Cara A. Yelverton, Aisling A. Geraghty, Calum J. Walsh, Ian J. O'Neill, Ida Busch Nielsan, Elaine M. Lawton, Rocio Sanchez-Gallardo, Sai Ravi Chandra Nori, Fergus Shanahan, Eileen F. Murphy, Douwe Van Sinderen, Paul D. Cotter, Fionnuala M. McAuliffe
Summary: This study aimed to investigate if maternal probiotic supplementation in pregnancy can affect the infant gut microbiome. The results showed that direct mother-to-infant strain transfer of the supplemented probiotic occurred, albeit infrequently. This study highlights the potential for maternal supplementation to introduce microbial strains into the infant microbiome.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Review
Nutrition & Dietetics
May Loong Tan, Izz Amirah Mohd Shukri, Jacqueline J. Ho, Elizabeth J. O'Sullivan, Amal Omer-Salim, Fionnuala M. McAuliffe
Summary: A breastfeeding-friendly city is a city that provides an enabling environment to support breastfeeding throughout a child's first 2 years or more. However, there are currently no established indicators for defining a breastfeeding-friendly city. This study identified common criteria such as policy, training & education, skilled breastfeeding support, and physical infrastructure, which could be developed into indicators. Further research is needed to determine the importance of these criteria and how they can be measured.
MATERNAL AND CHILD NUTRITION
(2023)
