Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages

3-Hydroxybutyrate dehydrogenase-2 and ferritin-H synergistically regulate intracellular iron

(2014) Zhuoming Liu et al.   FEBS Journal

Regulation of mammalian siderophore 2,5-DHBA in the innate immune response to infection

(2014) Zhuoming Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endogenous Siderophore 2,5-Dihydroxybenzoic Acid Deficiency Promotes Anemia and Splenic Iron Overload in Mice

(2014) Z. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Neisseria gonorrhoeae Modulates Iron-Limiting Innate Immune Defenses in Macrophages

(2014) Susu M. Zughaier et al.   PLoS One

Persistently Elevated Serum Interleukin-6 Predicts Mortality Among Adults Receiving Combination Antiretroviral Therapy in Botswana: Results from a Clinical Trial

(2013) Bethan McDonald et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Selective, potent blockade of the IRE1 and ATF6 pathways by 4-phenylbutyric acid analogues

(2013) Hui Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease

(2013) J A Alvarez et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes

(2013) Joanna M. Warszawska et al.   JOURNAL OF CLINICAL INVESTIGATION

Association of Functional Impairment with Inflammation and Immune Activation in HIV Type 1–Infected Adults Receiving Effective Antiretroviral Therapy

(2013) Kristine M. Erlandson, Amanda A. Allshouse, Catherine M. Jankowski, Eric J. Lee, Kevin M. Rufner, Brent E. Palmer et al.   JOURNAL OF INFECTIOUS DISEASES

1,25(OH)2 vitamin D suppresses macrophage migration and reverses atherogenic cholesterol metabolism in type 2 diabetic patients

(2013) Amy E. Riek et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase

(2013) Travis D Hull et al.   LABORATORY INVESTIGATION

Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy

(2013) Howard T Chang et al.   Nutrition & Metabolism

High-dose cholecalciferol reduces parathyroid hormone in patients with early chronic kidney disease: a pilot, randomized, double-blind, placebo-controlled trial

(2012) Jessica A Alvarez et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Unfolded protein response to autophagy as a promising druggable target for anticancer therapy

(2012) Dong Hoon Suh et al.   Annals of the New York Academy of Sciences

The role of autophagy in endoplasmic reticulum stress-induced pancreatic β cell death

(2012) Jia-Jing Yin et al.   Autophagy

The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer

(2012) Subhankar Chakraborty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

(2012) Shane Deegan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Heme Oxygenase-1 and Iron in Liver Inflammation: A Complex Alliance

(2012) Stephan Immenschuh et al.   CURRENT DRUG TARGETS

Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation

(2012) R E Grossmann et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Vitamin D Suppression of Endoplasmic Reticulum Stress Promotes an Antiatherogenic Monocyte/Macrophage Phenotype in Type 2 Diabetic Patients

(2012) Amy E. Riek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Siderophore-mediated iron trafficking in humans is regulated by iron

(2012) Zhuoming Liu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue

(2012) Noritaka Kawasaki et al.   Scientific Reports

Regulation of cellular iron metabolism

(2011) Jian Wang et al.   BIOCHEMICAL JOURNAL

ER stress drives Lipocalin 2 upregulation in prostate cancer cells in an NF-κB-dependent manner

(2011) Navin R Mahadevan et al.   BMC CANCER

Converging Pathways in the Occurrence of Endoplasmic Reticulum (ER) Stress in Huntingtons Disease

(2011) R. Vidal et al.   CURRENT MOLECULAR MEDICINE

Protein folding stress in neurodegenerative diseases: a glimpse into the ER

(2011) Soledad Matus et al.   CURRENT OPINION IN CELL BIOLOGY

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective role of Toll-like receptor 4 in experimental gonococcal infection of female mice

(2011) M Packiam et al.   Mucosal Immunology

Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype

(2011) Gaetano Cairo et al.   TRENDS IN IMMUNOLOGY

Hepcidin and Disorders of Iron Metabolism

(2010) Tomas Ganz et al.   Annual Review of Medicine

Modulation of iron homeostasis in macrophages by bacterial intracellular pathogens

(2010) Xin Pan et al.   BMC MICROBIOLOGY

A Mammalian Siderophore Synthesized by an Enzyme with a Bacterial Homolog Involved in Enterobactin Production

(2010) Laxminarayana R. Devireddy et al.   CELL

Polarization dictates iron handling by inflammatory and alternatively activated macrophages

(2010) G. Corna et al.   HAEMATOLOGICA

Iron Chelation Therapy in Hereditary Hemochromatosis and Thalassemia Intermedia: Regulatory and Non Regulatory Mechanisms of Increased Iron Absorption

(2010) George J. Kontoghiorghes et al.   HEMOGLOBIN

Adiponectin and Heme Oxygenase-1 Suppress TLR4/MyD88-Independent Signaling in Rat Kupffer Cells and in Mice after Chronic Ethanol Exposure

(2010) P. Mandal et al.   JOURNAL OF IMMUNOLOGY

Neisseria meningitidis capsular polysaccharides induce inflammatory responses via TLR2 and TLR4-MD-2

(2010) Susu M. Zughaier   JOURNAL OF LEUKOCYTE BIOLOGY

Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex

(2010) Guanhu Bao et al.   Nature Chemical Biology

Anti-inflammatory pathways and alcoholic liver disease: Role of an adiponectin/interleukin-10/heme oxygenase-1 pathway

(2010) Palash Mandal   WORLD JOURNAL OF GASTROENTEROLOGY

Neutrophil Gelatinase-Associated Lipocalin induces the expression of heme oxygenase-1 and superoxide dismutase 1, 2

(2009) Parisa Bahmani et al.   CELL STRESS & CHAPERONES

Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure

(2009) A. Yndestad et al.   EUROPEAN HEART JOURNAL

Differential regulation of iron homeostasis during human macrophage polarized activation

(2009) Stefania Recalcati et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway

(2009) Y. Nakayama et al.   JOURNAL OF BIOCHEMISTRY

ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity

(2009) Susana J. Oliveira et al.   PLoS One

ER Stress Controls Iron Metabolism Through Induction of Hepcidin

(2009) C. Vecchi et al.   SCIENCE

Pathways of renal injury in systemic gram-negative sepsis

(2008) T. M. El-Achkar et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression

(2008) Milan Theurl et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Siderocalin/Enterobactin Interaction: A Link between Mammalian Immunity and Bacterial Iron Transport1

(2008) Rebecca J. Abergel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Role of Lipocalin 2 in the Regulation of Inflammation in Adipocytes and Macrophages

(2008) Jinhui Zhang et al.   MOLECULAR ENDOCRINOLOGY

Discovery and Development of Toll-Like Receptor 4 (TLR4) Antagonists: A New Paradigm for Treating Sepsis and Other Diseases

(2008) Carlos G. Leon et al.   PHARMACEUTICAL RESEARCH

Potentiometric, spectrophotometric and calorimetric study on iron(III) and copper(II) complexes with 1,2-dimethyl-3-hydroxy-4-pyridinone

(2007) Valeria M. Nurchi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY