Review
Cardiac & Cardiovascular Systems
Michael I. Brener, Amirali Masoumi, Vivian G. Ng, Khodr Tello, Marcelo B. Bastos, William K. Cornwell, Steven Hsu, Ryan J. Tedford, Philipp Lurz, Karl-Philipp Rommel, Karl-Patrik Kresoja, Sherif F. Nagueh, Manreet K. Kanwar, Navin K. Kapur, Gurumurthy Hiremath, Mohammad Sarraf, Antoon J. M. Van Den Enden, Nicolas M. Van Mieghem, Paul M. Heerdt, Rebecca T. Hahn, Susheel K. Kodali, Gabriel T. Sayer, Nir Uriel, Daniel Burkhoff
Summary: Right ventricular pressure-volume analysis is a method independent of loading conditions to evaluate myocardial chamber performance and is becoming increasingly common in clinical and research settings. This review summarizes the basic techniques for PV loop measurement, analysis, and interpretation, as well as its application in clinically relevant topics.
CIRCULATION-HEART FAILURE
(2022)
Article
Physiology
Thiago O. C. Silva, Allan R. K. Sales, Gustavo S. M. Araujo, Guilherme W. P. Fonseca, Pedro G. S. Braga, Diego Faria, Helena N. M. Rocha, Natalia G. Rocha, Marta F. Lima, Charles Mady, Carlos E. Negrao, Maria Janieire N. N. Alves
Summary: This study found that disturbed blood flow acutely decreases FMD and increases EMP levels in patients with HFrEF, indicating that these patients are more susceptible to blood flow disturbances.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Naman S. Shetty, Vibhu Parcha, Peter Abdelmessih, Nirav Patel, Ammar A. Hasnie, Rajat Kalra, Ambarish Pandey, Khadijah Breathett, Alanna A. Morris, Garima Arora, Pankaj Arora
Summary: Sex-associated differences in clinical outcomes among left ventricular assist device recipients in the United States have been recognized, but an investigation of the social and clinical determinants of sex-associated differences is lacking.
CIRCULATION-HEART FAILURE
(2023)
Article
Medicine, General & Internal
Jong Shin Woo, Yeongmin Woo, Jeong Yoon Jang, Sang Jin Ha
Summary: This study demonstrates the safety of daily 4000 IU vitamin D dosage for patients with chronic heart failure. Although it did not improve endothelial function, it did improve 6-minute walk distance, symptoms, and left atrial diameter.
Article
Cardiac & Cardiovascular Systems
Peter Ivak, Ivan Netuka, Zuzana Tucanova, Peter Wohlfahrt, Miroslav Konarik, Ondrej Szarszoi, Sarka Novakova, Milos Kubanek, Vera Lanska, Jan Pitha
Summary: The study found that in patients implanted with HM3 left-ventricular assist systems, the artificial pulsatility provided by the device did not prevent deterioration of vascular function.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Ivan Cavero-Redondo, Alicia Saz-Lara, Irene Martinez-Garcia, Bruno Bizzozero-Peroni, Valentina Diaz-Goni, Ana Diez-Fernandez, Nerea Moreno-Herraiz, Carlos Pascual-Morena
Summary: This study aims to compare the efficacy of combined training and high intensity interval training (HIIT) on exercise capacity, diastolic function, endothelial function, and arterial stiffness in participants with HFpEF. The study will be a single-blind, 3-arm, randomized clinical trial (RCT) to evaluate the efficacy of physical exercise programs on exercise capacity, diastolic function, endothelial function, and arterial stiffness in HFpEF patients. The findings will be published in a peer-reviewed journal.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
F. Lu, D-J Zhai, F-F Liu, B-J Ji
Summary: This study found that obstructive sleep apnea in patients with chronic heart failure aggravates the inflammatory response, affecting heart function and vascular endothelial function.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2021)
Article
Cardiac & Cardiovascular Systems
Lukasz Pyka, Janusz Szkodzinski, Jacek Piegza, Malgorzata Swietlinska, Mariusz Gasior
Summary: Recently published studies suggest that percutaneous coronary intervention (PCI) has no significant impact on outcomes in patients with heart failure and stable coronary artery disease. The use of percutaneous mechanical circulatory support is growing, but its value is still uncertain. In cases where large areas of viable myocardium are ischemic, complete revascularization should be emphasized, and mechanical circulatory support is vital for hemodynamic stability during the procedure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Respiratory System
Stanislav Keranov, Oliver Doerr, Leili Jafari, Christian Troidl, Christoph Liebetrau, Steffen Kriechbaum, Till Keller, Sandra Voss, Timm Bauer, Jakob Lorenz, Manuel J. Richter, Khodr Tello, Henning Gall, Hossein A. Ghofrani, Eckhard Mayer, Christoph B. Wiedenroth, Stefan Guth, Holger Loerchner, Jochen Poeling, Prakash Chelladurai, Soni Savai Pullamsetti, Thomas Braun, Werner Seeger, Christian W. Hamm, Holger Nef
Summary: The study revealed that CILP1 is a novel biomarker associated with maladaptive RV function and PH, with significant differences in its concentrations among different cardiac pathology groups, showing potential in predicting maladaptive RV function.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Soeren J. Backhaus, Torben Lange, Elisabeth F. George, Kristian Hellenkamp, Roman J. Gertz, Marcus Billing, Rolf Wachter, Michael Steinmetz, Shelby Kutty, Uwe Raaz, Joachim Lotz, Tim Friede, Martin Uecker, Gerd Hasenfuss, Tim Seidler, Andreas Schuster
Summary: Real-time cardiac magnetic resonance (RT-CMR) exercise imaging can accurately diagnose HFpEF, providing a suitable noninvasive diagnostic alternative, which may be beneficial for routine clinical use pending further multicenter studies.
Review
Cardiac & Cardiovascular Systems
Alexander Van De Bruaene, Guido Claessen, Thomas Salaets, Marc Gewillig
Summary: The Fontan circulation is an effective palliative measure for children born with a single ventricle, but it also leads to elevated systemic venous pressures and reduced cardiac output. This article critically evaluates the components of the Fontan circulation and provides clues for optimizing this circulation system and future research.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Francesca Cortese, Marco Matteo Ciccone, Michele Gesualdo, Massimo Iacoviello, Maria Frigerio, Manlio Cipriani, Cristina Giannattasio, Alessandro Maloberti, Paola Giordano
Summary: The study compared endothelial function in patients with LVAD, heart transplant recipients, and heart failure patients on the transplant list. It was found that the continuous flow related to LVAD did not worsen endothelial function. Endothelial function was mainly influenced by CRP levels, suggesting inflammation as a key determinant.
Article
Cardiac & Cardiovascular Systems
Sabina Ugovsek, Andreja Rehberger Likozar, Sanjo Finderle, Gregor Poglajen, Renata Okrajsek, Bojan Vrtovec, Miran Sebestjen
Summary: The aim of this study was to investigate the association between endothelial dysfunction and the number of CD34(+) cells and TNF-alpha levels in patients with ischemic and non-ischemic heart failure. The results suggest that FMD and TNF-alpha are significant predictors of CD34(+) cell counts.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Biochemistry & Molecular Biology
Michael Groene, Dragos Andrei Duse, Nicolas Kramser, Niklas Ophoff, Hendrik Schweers, Fabian Voss, Christine Quast, Roberto Sansone, Christian Heiss, Christian Jung, Malte Kelm, Ralf Erkens
Summary: This study investigated the effect of cocoa flavanols on cardiorespiratory fitness in healthy elderly people. The results showed that cocoa flavanols significantly improved aerobic exercise capacity, blood pressure, and vascular function. The conclusion is that cocoa flavanols have the potential to preserve cardiovascular health in the elderly.
Article
Cardiac & Cardiovascular Systems
Alexander C. Egbe, William R. Miranda, C. Charles Jain, Patrick S. Kamath, Renuka R. Katta, Kartik Andi, Ahmed Y. Goda, Heidi M. Connolly
Summary: This study retrospectively analyzed the postoperative changes in hepatic and renal function in adults with congenital heart disease (CHD) undergoing isolated heart transplant. The results showed that CHD patients experienced significant improvement in hepatic and renal function after the transplant. The study suggests that selected CHD patients may have favorable outcomes with isolated heart transplant despite reduced hepatic and renal function and preoperative hepatic fibrosis.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
