Roles of EphA2 in Development and Disease

Predicting PDZ domain mediated protein interactions from structure

(2013) Shirley Hui et al.   BMC BIOINFORMATICS

Eph Receptors and Ephrin Signaling Pathways: A Role in Bone Homeostasis

(2012) Claire M. Edwards et al.   International Journal of Medical Sciences

Vascular Endothelial Growth Factor A in Intraocular Vascular Disease

(2012) Joan W. Miller et al.   OPHTHALMOLOGY

Ephs and ephrins resurface in inflammation, immunity, and atherosclerosis

(2012) Steven Daniel Funk et al.   PHARMACOLOGICAL RESEARCH

EPHA2 Polymorphisms and Age-Related Cataract in India

(2012) Periasamy Sundaresan et al.   PLoS One

Human Cataract Mutations in EPHA2 SAM Domain Alter Receptor Stability and Function

(2012) Jeong Eun Park et al.   PLoS One

Concepts and consequences of Eph receptor clustering

(2012) Peter W. Janes et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Bone cell interactions through Eph/ephrin

(2012) Koichi Matsuo et al.   Cell Adhesion & Migration

Ephrin/ephrin receptor expression during early stages of mouse inner ear development

(2011) Bernhard M. Saeger et al.   DEVELOPMENTAL DYNAMICS

Eph/ephrin signaling in cell-cell and cell-substrate adhesion

(2011) Arvinder Singh   Frontiers in Bioscience-Landmark

EphrinA1-EphA2 Signal Induces Compaction and Polarization of Madin-Darby Canine Kidney Cells by Inactivating Ezrin through Negative Regulation of RhoA

(2011) Yuki Wakayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diverse Roles of Eph/ephrin Signaling in the Mouse Lens

(2011) Catherine Cheng et al.   PLoS One

Eph/ephrin signaling in epidermal differentiation and disease

(2011) Samantha Lin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

EphrinB/EphB Signaling Controls Embryonic Germ Layer Separation by Contact-Induced Cell Detachment

(2011) Nazanin Rohani et al.   PLOS BIOLOGY

EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation

(2010) Seth S. Margolis et al.   CELL

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Patterning a Complex Organ: Branching Morphogenesis and Nephron Segmentation in Kidney Development

(2010) Frank Costantini et al.   DEVELOPMENTAL CELL

Architecture of Eph receptor clusters

(2010) J. P. Himanen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EphrinB reverse signaling in cell-cell adhesion

(2010) Hyun-Shik Lee et al.   Cell Adhesion & Migration

EphA2 overexpression is associated with lack of hormone receptor expression and poor outcome in endometrial cancer

(2009) Aparna A. Kamat et al.   CANCER

Liver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-κB signaling pathway

(2009) Yu-Xiong Feng et al.   HEPATOLOGY

Dominant cataract formation in association with a vimentin assembly disrupting mutation

(2009) M. Muller et al.   HUMAN MOLECULAR GENETICS

Mutations of theEPHA2receptor tyrosine kinase gene cause autosomal dominant congenital cataract

(2009) Tianxiao Zhang et al.   HUMAN MUTATION

Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity

(2009) Haina Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bidirectional Signaling through EphrinA2-EphA2 Enhances Osteoclastogenesis and Suppresses Osteoblastogenesis

(2009) Naoko Irie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility

(2009) T. Yamazaki et al.   JOURNAL OF CELL SCIENCE

Regulation of Mammary Gland Branching Morphogenesis by EphA2 Receptor Tyrosine Kinase

(2009) David Vaught et al.   MOLECULAR BIOLOGY OF THE CELL

EPHA2 Is Associated with Age-Related Cortical Cataract in Mice and Humans

(2009) Gyungah Jun et al.   PLoS Genetics

Osteoclast–osteoblast communication

(2008) Koichi Matsuo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Eph Receptors and Ephrins in Cancer: Common Themes and Controversies

(2008) J. Chen et al.   CANCER RESEARCH

Mammary development in the embryo and adult: a journey of morphogenesis and commitment

(2008) C. J. Watson et al.   DEVELOPMENT

Eph/ephrin signaling: networks

(2008) D. Arvanitis et al.   GENES & DEVELOPMENT

Eph/ephrin signaling in epithelial development and homeostasis

(2008) Hui Miao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors

(2008) Roberta Noberini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Functional Analysis of Phosphorylated Tyrosine Residues within EphA2 Receptor Tyrosine Kinase

(2008) Wei Bin Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism

(2008) W. B. Fang et al.   JOURNAL OF CELL SCIENCE

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

(2008) Dana M. Brantley-Sieders et al.   JOURNAL OF CLINICAL INVESTIGATION

The EphA2 Receptor and EphrinA1 Ligand in Solid Tumors: Function and Therapeutic Targeting

(2008) J. Wykosky et al.   MOLECULAR CANCER RESEARCH

Bidirectional modulation of synaptic functions by Eph/ephrin signaling

(2008) Rüdiger Klein   NATURE NEUROSCIENCE

p75NTR Mediates Ephrin-A Reverse Signaling Required for Axon Repulsion and Mapping

(2008) Yoo-Shick Lim et al.   NEURON

SAM Domain-Based Protein Oligomerization Observed by Live-Cell Fluorescence Fluctuation Spectroscopy

(2008) Brian D. Slaughter et al.   PLoS One

Prognostic Breast Cancer Signature Identified from 3D Culture Model Accurately Predicts Clinical Outcome across Independent Datasets

(2008) Katherine J. Martin et al.   PLoS One

Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract

(2008) M. A. Cooper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA