Understanding the Molecular Circuitry of Cell Lineage Specification in the Early Mouse Embryo

Functional and Mechanistic Diversity of Distal Transcription Enhancers

(2011) Michael Bulger et al.   CELL

Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming

(2011) Yufeng Li et al.   CELL RESEARCH

Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates

(2011) Katie McDole et al.   DEVELOPMENTAL BIOLOGY

Trophectoderm Lineage Determination in Cattle

(2011) Debra K. Berg et al.   DEVELOPMENTAL CELL

A mouse is not a cow

(2011) Janet Rossant   NATURE

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

(2011) Kristine Williams et al.   NATURE

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells

(2011) Hao Wu et al.   NATURE

LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells

(2011) Antonio Adamo et al.   NATURE CELL BIOLOGY

Oct4 kinetics predict cell lineage patterning in the early mammalian embryo

(2011) Nicolas Plachta et al.   NATURE CELL BIOLOGY

Regulation of X-chromosome inactivation by the X-inactivation centre

(2011) Sandrine Augui et al.   NATURE REVIEWS GENETICS

What is the role of maternally provided Cdx2 mRNA in early mouse embryogenesis?

(2011) Alexander W. Bruce   REPRODUCTIVE BIOMEDICINE ONLINE

Cell fate in the early mouse embryo: sorting out the influence of developmental history on lineage choice

(2011) Samantha A. Morris   REPRODUCTIVE BIOMEDICINE ONLINE

Response: Cell fate in the early mouse embryo – sorting out the influence of developmental history on lineage choice

(2011) Yojiro Yamanaka   REPRODUCTIVE BIOMEDICINE ONLINE

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells

(2010) Keriayn N. Smith et al.   Cell Stem Cell

Developmental control of the early mammalian embryo: competition among heterogeneous cells that biases cell fate

(2010) Alexander W Bruce et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cellular dynamics in the early mouse embryo: from axis formation to gastrulation

(2010) Sonja Nowotschin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Initiation of trophectoderm lineage specification in mouse embryos is independent of Cdx2

(2010) G. Wu et al.   DEVELOPMENT

A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst

(2010) J. Artus et al.   DEVELOPMENT

Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2

(2010) A. Ralston et al.   DEVELOPMENT

Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo

(2010) Agnieszka Jedrusik et al.   DEVELOPMENTAL BIOLOGY

Nanog is required for primitive endoderm formation through a non-cell autonomous mechanism

(2010) Daniel M. Messerschmidt et al.   DEVELOPMENTAL BIOLOGY

Individual blastomeres of 16- and 32-cell mouse embryos are able to develop into foetuses and mice

(2010) Andrzej K. Tarkowski et al.   DEVELOPMENTAL BIOLOGY

The primitive endoderm lineage of the mouse blastocyst: Sequential transcription factor activation and regulation of differentiation by Sox17

(2010) Jérôme Artus et al.   DEVELOPMENTAL BIOLOGY

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst

(2010) Guoji Guo et al.   DEVELOPMENTAL CELL

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

(2010) K. K. Niakan et al.   GENES & DEVELOPMENT

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Epigenetic modifications in pluripotent and differentiated cells

(2010) Alexander Meissner   NATURE BIOTECHNOLOGY

Global Chromatin Architecture Reflects Pluripotency and Lineage Commitment in the Early Mouse Embryo

(2010) Kashif Ahmed et al.   PLoS One

Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo

(2010) S. A. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vertebrate Protein CTCF and its Multiple Roles in a Large-Scale Regulation of Genome Activity

(2009) L. Nikolaev et al.   CURRENT GENOMICS

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo

(2009) J. Nichols et al.   DEVELOPMENT

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

(2009) J. Rossant et al.   DEVELOPMENT

Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst

(2009) Sigolène M. Meilhac et al.   DEVELOPMENTAL BIOLOGY

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

GATA3 Is Selectively Expressed in the Trophectoderm of Peri-implantation Embryo and Directly RegulatesCdx2Gene Expression

(2009) Pratik Home et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting

(2009) Mary E. Donohoe et al.   NATURE

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Transcription-Independent Heritability of Induced Histone Modifications in the Mouse Preimplantation Embryo

(2009) Matthew D. VerMilyea et al.   PLoS One

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

X Chromosome Dosage Compensation: How Mammals Keep the Balance

(2008) Bernhard Payer et al.   Annual Review of Genetics

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst

(2008) B. Plusa et al.   DEVELOPMENT

Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse

(2008) S. J. Arnold et al.   DEVELOPMENT

Dynamic GATA6 expression in primitive endoderm formation and maturation in early mouse embryogenesis

(2008) Kathy Q. Cai et al.   DEVELOPMENTAL DYNAMICS

Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo

(2008) A. Jedrusik et al.   GENES & DEVELOPMENT

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5

(2008) Ray Kit Ng et al.   NATURE CELL BIOLOGY

Molecular Coupling of Xist Regulation and Pluripotency

(2008) P. Navarro et al.   SCIENCE

Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo

(2007) Amy Ralston et al.   DEVELOPMENTAL BIOLOGY

Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst

(2007) François Gerbe et al.   DEVELOPMENTAL BIOLOGY

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

(2007) Noriyuki Nishioka et al.   MECHANISMS OF DEVELOPMENT