Discovery of Potent Disheveled/Dvl Inhibitors Using Virtual Screening Optimized With NMR-Based Docking Performance Index

Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies

(2016) Jiwon Choi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Comprehensive evaluation of ten docking programs on a diverse set of protein–ligand complexes: the prediction accuracy of sampling power and scoring power

(2016) Zhe Wang et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Inexpensive Method for Selecting Receptor Structures for Virtual Screening

(2015) Zunnan Huang et al.   Journal of Chemical Information and Modeling

Toward a Benchmarking Data Set Able to Evaluate Ligand- and Structure-based Virtual Screening Using Public HTS Data

(2015) Martin Lindh et al.   Journal of Chemical Information and Modeling

Wnt signaling in stem and cancer stem cells

(2013) Jane D Holland et al.   CURRENT OPINION IN CELL BIOLOGY

Accidental Interaction between PDZ Domains and Diclofenac Revealed by NMR-Assisted Virtual Screening

(2013) Takeshi Tenno et al.   MOLECULES

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Drugging Wnt signalling in cancer

(2012) Paul Polakis   EMBO JOURNAL

1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1

(2011) Yoshitaka Umetsu et al.   Biomolecular NMR Assignments

Frizzled7 as an emerging target for cancer therapy

(2011) Taj D. King et al.   CELLULAR SIGNALLING

The wnt/β-catenin signaling pathway: A potential therapeutic target in the treatment of triple negative breast cancer

(2011) Taj D. King et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

FRED Pose Prediction and Virtual Screening Accuracy

(2011) Mark McGann   Journal of Chemical Information and Modeling

FZD7 has a critical role in cell proliferation in triple negative breast cancer

(2011) L Yang et al.   ONCOGENE

β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

(2010) Felipe C Geyer et al.   MODERN PATHOLOGY

Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways

(2010) Naoko Takebe et al.   Nature Reviews Clinical Oncology

SAHG, a comprehensive database of predicted structures of all human proteins

(2010) Chie Motono et al.   NUCLEIC ACIDS RESEARCH

Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled

(2009) Ho-Jin Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of tripeptides recognized by the PDZ domain of Dishevelled

(2009) Ho-Jin Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Dishevelled: The hub of Wnt signaling

(2009) Chan Gao et al.   CELLULAR SIGNALLING

Discovery and Characterization of a Small Molecule Inhibitor of the PDZ Domain of Dishevelled

(2009) David Grandy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Inhibition of Wnt signaling by Dishevelled PDZ peptides

(2009) Yingnan Zhang et al.   Nature Chemical Biology

ASEDock-Docking Based on Alpha Spheres and Excluded Volumes

(2008) Junichi Goto et al.   Journal of Chemical Information and Modeling