Article
Neurosciences
Zachary Adam Yaple, Serenella Tolomeo, Rongjun Yu
Summary: This study investigated prediction error processing in depression and schizophrenia patients through meta-analyses, finding differences in brain activity between the two patient groups, suggesting a potential role of dopamine-rich areas in encoding prediction errors in both disorders.
HUMAN BRAIN MAPPING
(2021)
Article
Biology
Jessica N. Goedhoop, Bastijn J. G. van den Boom, Rhiannon Robke, Felice Veen, Lizz Fellinger, Wouter van Elzelingen, Tara Arbab, Ingo Willuhn
Summary: This study systematically investigates the role of dopamine in processing aversive stimuli and finds that NAC dopamine primarily tracks the prediction and duration of aversive events, rather than aversive prediction errors.
Article
Anatomy & Morphology
A. Santo-Angles, P. Fuentes-Claramonte, I Argila-Plaza, M. Guardiola-Ripoll, C. Almodovar-Paya, J. Munuera, P. J. McKenna, E. Pomarol-Clotet, J. Radua
Summary: The study proposed a model fitting approach that combines behavioral and neural data to fit computational models of reinforcement learning. Q-learning outperformed actor-critic models in both behavioral and neural levels, while incorporating neuroimaging data improved the fit of actor-critic models. The research observed action-value and state-value prediction error signals in the striatum, and identified a functional hemispheric asymmetry regarding prediction-error driven learning.
BRAIN STRUCTURE & FUNCTION
(2021)
Article
Neurosciences
Serenella Tolomeo, Alex Baldacchino, J. Douglas Steele
Summary: Alcohol-related morbidities and mortality are widespread globally, leading to 3 million deaths each year in young adults directly attributable to alcohol. Cue-induced alcohol craving has been identified as an abnormal associative learning, with craving linked to the expected reward value. Harmful use of alcohol is associated with increased time spent obtaining and using alcohol, as well as self-neglect. In this study, binge drinkers showed diminished encoding of reward delivery cues and the magnitude of abnormality correlated with problematic alcohol use ratings.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Joana Carvalheiro, Vasco A. Conceicao, Ana Mesquita, Ana Seara-Cardoso
Summary: Acute stress affects individuals' behavior in seeking monetary gains and impairs neural signaling of prediction errors, particularly positive errors, during reinforcement learning.
NEUROBIOLOGY OF STRESS
(2021)
Article
Neurosciences
M. Thiele, K. S. L. Yuen, A. V. M. Gerlicher, R. Kalisch
Summary: Animal studies suggest that fear extinction learning involves prediction error signal encoded by dopamine neurons, similar to reward learning. However, the mechanisms in human fear extinction learning are still not fully understood, with previous findings indicating correlations with genetic variations related to dopamine.
Article
Neurosciences
Cristian B. Calderon, Esther De Loof, Kate Ergo, Anna Snoeck, Carsten N. Boehler, Tom Verguts
Summary: Behavioral evidence suggests that reward prediction errors play a key role in episodic memory acquisition. In a novel task where RPEs were manipulated, fMRI results confirmed that signed RPEs are encoded in the ventral striatum and mediate their effects on episodic memory accuracy. Connectivity between processing areas and the hippocampus and ventral striatum increased with RPE value, supporting their central role in episodic memory formation.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Insa Schlossmacher, Jacky Dilly, Ina Protmann, David Hofmann, Torge Dellert, Marie-Luise Roth-Paysen, Robert Moeck, Maximilian Bruchmann, Thomas Straube
Summary: This study investigated the hierarchical cortical structure of neural mismatch responses and found that the relative contributions of prediction error-related processes and adaptation processes vary across different brain regions.
Article
Anesthesiology
Robert Hoskin, Deborah Talmi
Summary: This study provides the first evidence that the left dorsal anterior insula responds to pain in a manner consistent with the adaptive coding of pain prediction error. The results advance our understanding of the neural basis of pain perception and can contribute to improving analgesic treatments.
EUROPEAN JOURNAL OF PAIN
(2023)
Article
Forestry
Elijah Allensworth, Hailemariam Temesgen, Bryce Frank, Andrew Gray
Summary: The study compared the impact factors on the accuracy of HTCB predictions and found that the NMEM model performed best when the subsample size was greater than one. Despite generally smaller RMSEs, the NMEM model still exhibited significant biases when the subsample size was less than three trees per plot.
FOREST ECOLOGY AND MANAGEMENT
(2021)
Article
Neurosciences
Gina Joue, Karima Chakroun, Janine Bayer, Jan Glaescher, Lei Zhang, Johannes Fuss, Nora Hennies, Tobias Sommer
Summary: The study found that women showed enhanced brain activity related to reward prediction error compared to men, and this effect was further amplified when estrogen levels were elevated in both sexes. However, both female sex and estrogen slowed adaptation to reward prediction errors, resulting in a smaller learning rate.
Article
Neurosciences
Yinghua Yu, Laurentius Huber, Jiajia Yang, Masaki Fukunaga, Yuhui Chai, David C. Jangraw, Gang Chen, Daniel A. Handwerker, Peter J. Molfese, Yoshimichi Ejima, Norihiro Sadato, Jinglong Wu, Peter A. Bandettini
Summary: The human brain continuously generates predictions of sensory input and calculates prediction errors to update internal predictions. Different layers in the human area 3b contribute differently to the processing of temporal prediction error during tactile tasks.
Review
Neurosciences
Yujun Deng, Da Song, Junjun Ni, Hong Qing, Zhenzhen Quan
Summary: Learning is a complex process where our opinions and decisions can be easily influenced by unexpected information. The neural mechanism underlying revision and correction during learning is still unclear.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Neurosciences
Xun Yang, Yuan Song, Yuhan Zou, Yilin Li, Jianguang Zeng
Summary: This study investigated the neural correlates of processing prediction error signals in schizophrenia patients and healthy controls. The results showed that schizophrenia patients exhibited increased activity in certain brain regions, such as the precentral gyrus and middle frontal gyrus, and reduced activity in the mesolimbic circuit when processing prediction errors. Additionally, abnormal activity was found in frontal areas and mesolimbic areas during encoding of prediction error signals in schizophrenia patients.
Review
Behavioral Sciences
Kent C. Berridge
Summary: Individuals' desires are influenced not only by memories and learned predictions, but also by the independent operating rules of motivational incentive salience. Even outcomes that are remembered and predicted to be negative can be positively wanted.
TRENDS IN COGNITIVE SCIENCES
(2023)
Article
Neurosciences
Florens Goldbeck, Alina Haipt, David Rosenbaum, Tim Rohe, Andreas J. Fallgatter, Martin Hautzinger, Ann-Christine Ehlis
FRONTIERS IN HUMAN NEUROSCIENCE
(2019)
Article
Clinical Neurology
Roy F. Riascos, Arash Kamali, Reza Hakimelahi, Benson Mwangi, Pejman Rabiei, Rachael D. Seidler, Barzin B. Behzad, Zafer Keser, Larry A. Kramer, Khader M. Hasan
JOURNAL OF NEUROIMAGING
(2019)
Article
Neurosciences
Brian Greeley, Rachael D. Seidler
JOURNAL OF NEUROPHYSIOLOGY
(2019)
Article
Neurosciences
Kaitlin Cassady, Holly Gagnon, Poortata Lalwani, Molly Simmonite, Bradley Foerster, Denise Park, Scott J. Peltier, Myria Petrou, Stephan F. Taylor, Daniel H. Weissman, Rachael D. Seidler, Thad A. Polk
Article
Clinical Neurology
Jessica K. Lee, Vincent Koppelmans, Roy F. Riascos, Khader M. Hasan, Ofer Pasternak, Ajitkumar P. Mulavara, Jacob J. Bloomberg, Rachael D. Seidler
Article
Clinical Neurology
Holly Gagnon, Molly Simmonite, Kaitlin Cassady, Jordan Chamberlain, Erin Freiburger, Poortata Lalwani, Shannon Kelley, Bradley Foerster, Denise C. Park, Myria Petrou, Rachael D. Seidler, Stephan F. Taylor, Daniel H. Weissman, Thad A. Polk
Article
Psychology, Biological
Basil Wahn, Tim Rohe, Anika Gearhart, Alan Kingstone, Scott Sinnett
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2020)
Article
Biology
Ulrik Beierholm, Tim Rohe, Ambra Ferrari, Oliver Stegle, Uta Noppeney
Article
Neurosciences
Beatrix Barth, Tim Rohe, Saskia Deppermann, Andreas Jochen Fallgatter, Ann-Christine Ehlis
Summary: This study aimed to investigate the neuroelectric mechanisms of performance monitoring in high-impulsive and low-impulsive individuals. Results showed that high-impulsive individuals exhibited less effective motor execution processes and lower parieto-occipital theta ITPC could predict higher reaction time and variability.
HUMAN BRAIN MAPPING
(2021)
Article
Geriatrics & Gerontology
Jordan D. Chamberlain, Holly Gagnon, Poortata Lalwani, Kaitlin E. Cassady, Molly Simmonite, Rachael D. Seidler, Stephan F. Taylor, Daniel H. Weissman, Denise C. Park, Thad A. Polk
Summary: With aging, there is a decline in neural distinctiveness which may be related to a decrease in GABA levels, leading to less distinct neural activation patterns in the ventral visual cortex of older adults.
NEUROBIOLOGY OF AGING
(2021)
Review
Geriatrics & Gerontology
Tyler Fettrow, Kathleen Hupfeld, Grant Tays, David J. Clark, Patricia A. Reuter-Lorenz, Rachael D. Seidler
Summary: Studies have shown that older adults exhibit increased brain activity when performing cognitive tasks, which may indicate neural dysfunction or neural compensation. Including multiple task difficulty levels in future research can lead to a more advanced understanding of age-related changes in locomotor brain activity and support the development of targeted neural rehabilitation techniques.
NEUROBIOLOGY OF AGING
(2021)
Article
Chemistry, Analytical
Tian Bao, Fatemeh Noohi, Catherine Kinnaird, Wendy J. Carender, Vincent J. Barone, Geeta Peethambaran, Susan L. Whitney, Rachael D. Seidler, Kathleen H. Sienko
Summary: Long-term balance training with vibrotactile sensory augmentation has sustained effects on balance improvement and induces changes in brain activity pattern among community-dwelling healthy older adults.
Article
Neurosciences
Grant D. Tays, Kathleen E. Hupfeld, Heather R. McGregor, Nichole E. Beltran, Igor S. Kofman, Yiri E. De Dios, Edwin R. Mulder, Jacob J. Bloomberg, Ajitkumar P. Mulavara, Scott J. Wood, Rachael D. Seidler
Summary: Altered vestibular signaling and body unloading in microgravity leads to sensory reweighting and adaptation. The effectiveness of daily artificial gravity (AG) for mitigating brain and/or behavioral changes in 60 days of head-down tilt bed rest (HDBR) was examined. Results showed that the AG group exhibited similar behavioral adaptation effects as the control group (CTRLs), but had reduced brain activation in certain areas during the late HDBR phase. These findings suggest that AG may lead to a reduced recruitment of brain activity for motor processes and sensorimotor adaptation.
Article
Neurosciences
Heather R. McGregor, Jessica K. Lee, Edwin R. Mulder, Yiri E. De Dios, Nichole E. Beltran, Scott J. Wood, Jacob J. Bloomberg, Ajitkumar P. Mulavara, Rachael D. Seidler
Summary: The study investigated how artificial gravity (AG) alters resting-state brain functional connectivity changes during head-down tilt bed rest (HDBR), a spaceflight analog. The results showed that AG can change the brain functional connectivity during HDBR and reduce balance and mobility declines. These findings suggest that AG could be an effective countermeasure for the reduced somatosensory stimulation that occurs in microgravity and HDBR.
Article
Neurosciences
Burak Erdeniz, John Done