Journal
FRONTIERS IN NEUROINFORMATICS
Volume 5, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fninf.2011.00037
Keywords
database; neuroimaging; longitudinal; multi-center; MRI; data querying; imaging data; behavioral data
Funding
- National Institute of Child Health and Human Development
- National Institute of Drug Abuse
- National Institute of Mental Health
- National Institute of Neurological Disorders and Stroke [N01-HD02-3343, N01-MH9-0002, N01-NS-9- 2314, N01-NS-9-2315, N01-NS-9-2316, N01-NS-9-2317, N01-NS-9-2319, N01-NS-9-2320]
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Longitudinal Online Research and Imaging System (LORIS) is a modular and extensible web-based data management system that integrates all aspects of a multi-center study: from heterogeneous data acquisition (imaging, clinical, behavior, and genetics) to storage, processing, and ultimately dissemination. It provides a secure, user-friendly, and streamlined platform to automate the flow of clinical trials and complex multi-center studies. A subject-centric internal organization allows researchers to capture and subsequently extract all information, longitudinal or cross-sectional, from any subset of the study cohort. Extensive error checking and quality control procedures, security, data management, data querying, and administrative functions provide LORIS with a triple capability (1) continuous project coordination and monitoring of data acquisition (2) data storage/cleaning/querying, (3) interface with arbitrary external data processing pipelines. LORIS is a complete solution that has been thoroughly tested through a full 10 year life cycle of a multi center longitudinal project(1) and is now supporting numerous international neurodevelopment and neurodegeneration research projects.
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