mTOR signaling contributes to motor skill learning in mice

Blocking mTORC1 activity by rapamycin leads to impairment of spatial memory retrieval but not acquisition in C57BL/6J mice

(2012) Alev Deli et al.   BEHAVIOURAL BRAIN RESEARCH

Mammalian Target of Rapamycin Complex 1 (mTORC1) and 2 (mTORC2) Control the Dendritic Arbor Morphology of Hippocampal Neurons

(2012) Malgorzata Urbanska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway

(2012) Delia M. Talos et al.   PLoS One

Reduced phosphorylation of the mTOR signaling pathway components in the amygdala of rats exposed to chronic stress

(2012) Agata Chandran et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

Blockade of NMDA receptors 2A subunit in the dorsal striatum impairs the learning of a complex motor skill.

(2011) Julie Lemay-Clermont et al.   BEHAVIORAL NEUROSCIENCE

Differential gene expression profiling in the mouse brain during motor skill learning: Focus on the striatum structure

(2011) Guylaine D’Amours et al.   BEHAVIOURAL BRAIN RESEARCH

Impairment of object recognition memory by rapamycin inhibition of mTOR in the amygdala or hippocampus around the time of learning or reactivation

(2011) Paulo F.C. Jobim et al.   BEHAVIOURAL BRAIN RESEARCH

Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory

(2011) Paulo F.C. Jobim et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder

(2011) Courtney S. Jernigan et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Molecular substrates of action control in cortico-striatal circuits

(2011) Michael W. Shiflett et al.   PROGRESS IN NEUROBIOLOGY

TOR on the brain

(2010) Michael G. Garelick et al.   EXPERIMENTAL GERONTOLOGY

Translational Control Mechanisms in Long-lasting Synaptic Plasticity and Memory

(2010) Christos Gkogkas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrastriatal inhibition of extracellular signal-regulated kinases impaired the consolidation phase of motor skill learning

(2010) Geneviève Bureau et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Activation of mammalian target of rapamycin signaling in spatial learning

(2010) Sihua Qi et al.   NEUROSCIENCE RESEARCH

Making synaptic plasticity and memory last: mechanisms of translational regulation

(2009) J. D. Richter et al.   GENES & DEVELOPMENT

Biphasic Activation of the mTOR Pathway in the Gustatory Cortex Is Correlated with and Necessary for Taste Learning

(2009) K. Belelovsky et al.   JOURNAL OF NEUROSCIENCE

Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill

(2009) Henry H Yin et al.   NATURE NEUROSCIENCE

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Dopaminergic Modulation of Auditory Cortex-Dependent Memory Consolidation through mTOR

(2008) Horst Schicknick et al.   CEREBRAL CORTEX

Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex

(2008) L. Sui et al.   LEARNING & MEMORY

Striatal Plasticity and Basal Ganglia Circuit Function

(2008) Anatol C. Kreitzer et al.   NEURON

Role of mTOR in physiology and pathology of the nervous system

(2007) Lukasz Swiech et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS