Non-viral gene therapy that targets motor neurons in vivo

Storage stability of optimal liposome–polyethylenimine complexes (lipopolyplexes) for DNA or siRNA delivery

(2014) Alexander Ewe et al.   Acta Biomaterialia

Specific Retrograde Transduction of Spinal Motor Neurons Using Lentiviral Vectors Targeted to Presynaptic NMJ Receptors

(2014) I Eleftheriadou et al.   MOLECULAR THERAPY

The Extracellular Domain of Neurotrophin Receptor p75 as a Candidate Biomarker for Amyotrophic Lateral Sclerosis

(2014) Stephanie R. Shepheard et al.   PLoS One

Spinal muscular atrophy: Development and implementation of potential treatments

(2013) W. David Arnold et al.   ANNALS OF NEUROLOGY

Amyotrophic lateral sclerosis: Problems and prospects

(2013) Jemeen Sreedharan et al.   ANNALS OF NEUROLOGY

Controversies and priorities in amyotrophic lateral sclerosis

(2013) Martin R Turner et al.   LANCET NEUROLOGY

Pharmacokinetics and transgene expression of implanted polyethylenimine-based pDNA complexes

(2013) Laura Rose et al.   Biomaterials Science

The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes

(2012) Lee A. Davies et al.   BIOMATERIALS

Dilemmas in the reliable estimation of the in-vitro cell viability in magnetic nanoparticle engineering: which tests and what protocols?

(2012) Clare Hoskins et al.   Nanoscale Research Letters

Special delivery: targeted therapy with small RNAs

(2011) D Peer et al.   GENE THERAPY

How to screen non-viral gene delivery systems in vitro?

(2011) Ethlinn V.B. van Gaal et al.   JOURNAL OF CONTROLLED RELEASE

Non-viral gene therapy for neurological diseases, with an emphasis on targeted gene delivery

(2011) Mary-Louise Rogers et al.   JOURNAL OF CONTROLLED RELEASE

Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations

(2011) Terese Magnusson et al.   JOURNAL OF GENE MEDICINE

Barriers to Non-Viral Vector-Mediated Gene Delivery in the Nervous System

(2011) Francisco C. Pérez-Martínez et al.   PHARMACEUTICAL RESEARCH

Cationic Nanomicelles for Delivery of Plasmids Encoding Interleukin-4 and Interleukin-10 for Prevention of Autoimmune Diabetes in Mice

(2011) Rhishikesh Mandke et al.   PHARMACEUTICAL RESEARCH

Maltose- and maltotriose-modified, hyperbranched poly(ethylene imine)s (OM-PEIs): Physicochemical and biological properties of DNA and siRNA complexes

(2010) Sabrina Höbel et al.   JOURNAL OF CONTROLLED RELEASE

ProNGF mediates death of Natural Killer cells through activation of the p75NTR–sortilin complex

(2010) Mary-Louise Rogers et al.   JOURNAL OF NEUROIMMUNOLOGY

Receptor-Mediated Abeta Amyloid Antibody Targeting to Alzheimer’s Disease Mouse Brain

(2010) Qing-Hui Zhou et al.   MOLECULAR PHARMACEUTICS

Neuroprotection by Gene Therapy Targeting Mutant SOD1 in Individual Pools of Motor Neurons Does not Translate Into Therapeutic Benefit in fALS Mice

(2010) Chris Towne et al.   MOLECULAR THERAPY

Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier

(2010) David Schaffert et al.   PHARMACEUTICAL RESEARCH

Stability of poly(ethylene glycol)-graft-polyethylenimine copolymer/DNA complexes: influences of PEG molecular weight and PEGylation degree

(2009) Xin Luo et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival

(2009) Neil A Shneider et al.   Neural Development

In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(–PEG)/siRNA complexes

(2009) Anastasia Malek et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS

Systemic AAV6 Delivery Mediating RNA Interference Against SOD1: Neuromuscular Transduction Does Not Alter Disease Progression in fALS Mice

(2008) Chris Towne et al.   MOLECULAR THERAPY

Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking

(2007) Dusan Matusica et al.   JOURNAL OF NEUROSCIENCE RESEARCH