In silico prediction of a disease-associated STIL mutant and its affect on the recruitment of centromere protein J (CENPJ)

Computational investigation of pathogenic nsSNPs in CEP63 protein

(2012) Ambuj Kumar et al.   GENE

Studies on Adaptability of Binding Residues Flap Region of TMC-114 Resistance HIV-1 Protease Mutants

(2012) Rituraj Purohit et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

In silico investigation of molecular mechanism of laminopathy caused by a point mutation (R482W) in lamin A/C protein

(2011) Vidya Rajendran et al.   AMINO ACIDS

Computational analysis of genetic network involved in pancreatic cancer in human

(2011) Mrinal Mishra et al.   BMC BIOINFORMATICS

Improving the prediction of disease-related variants using protein three-dimensional structure

(2011) Emidio Capriotti et al.   BMC BIOINFORMATICS

The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation

(2011) Chieh-Ju C Tang et al.   EMBO JOURNAL

Performance of mutation pathogenicity prediction methods on missense variants

(2011) Janita Thusberg et al.   HUMAN MUTATION

Spindle positioning in human cells relies on proper centriole formation and on the microcephaly proteins CPAP and STIL

(2011) D. Kitagawa et al.   JOURNAL OF CELL SCIENCE

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

Autosomal recessive primary microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuum

(2011) Saqib Mahmood et al.   Orphanet Journal of Rare Diseases

Relationship between mutation of serine residue at 315th position in M. tuberculosis catalase-peroxidase enzyme and Isoniazid susceptibility: An in silico analysis

(2010) Rituraj Purohit et al.   JOURNAL OF MOLECULAR MODELING

Mutations in STIL, Encoding a Pericentriolar and Centrosomal Protein, Cause Primary Microcephaly

(2009) Arun Kumar et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Automated inference of molecular mechanisms of disease from amino acid substitutions

(2009) B. Li et al.   BIOINFORMATICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Identification, analysis, and prediction of protein ubiquitination sites

(2009) Predrag Radivojac et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Genetics and Biology of Microcephaly and Lissencephaly

(2009) Ganeshwaran H. Mochida   Seminars in Pediatric Neurology

Research Spotlight: New multiparameter bioanalytical technologies for applications in personalized medicine, drug discovery and fundamental biology

(2009) Ryan C Bailey   Bioanalysis

Structural basis for the resilience of Darunavir (TMC114) resistance major flap mutations of HIV-1 protease

(2009) Rituraj Purohit et al.   Interdisciplinary Sciences-Computational Life Sciences

SCL/TAL1 Interrupting Locus Derepresses GLI1 from the Negative Control of Suppressor-of-Fused in Pancreatic Cancer Cell

(2008) K. Kasai et al.   CANCER RESEARCH

Studies on flexibility and binding affinity of Asp25 of HIV-1 protease mutants

(2008) Rituraj Purohit et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Database resources of the National Center for Biotechnology Information

(2008) E. W. Sayers et al.   NUCLEIC ACIDS RESEARCH