Article
Clinical Neurology
David Leander Rimmele, Elina Larissa Petersen, Eckhard Schlemm, Simon S. Kessner, Marvin Petersen, Carola Mayer, Bastian Cheng, Tanja Zeller, Christoph Waldeyer, Christian-Alexander Behrendt, Christian Gerloff, Gotz Thomalla
Summary: This study aimed to investigate the association between carotid plaques and flow velocities with peak width mean diffusivity and white matter hyperintensities, independent of shared risk factors. The results showed that both carotid plaques and low flow velocities were significantly associated with higher white matter hyperintensities and peak width mean diffusivity.
Article
Medicine, General & Internal
Janusz Sadowski, Ryszard Targonski, Piotr Cyganski, Paulina Nowek, Magdalena Starek-Stelmaszczyk, Katarzyna Zajac, Judyta Juranek, Joanna Wojtkiewicz, Andrzej Rynkiewicz
Summary: Current data suggests that heart failure (HF) is associated with inflammation, microvascular dysfunction, and remodeling. This study compared structural changes in retinal arterioles and carotid arteries between HF patients and patients without heart failure. The results showed that HF patients had higher arterial thickness and wall-to-lumen ratio compared to non-HF patients, and there was a correlation between retinal arterioles and carotid arteries.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Mechanics
Piru Mohan Khan, Siddharth D. Sharma, Suman Chakraborty, Somnath Roy
Summary: Increased heart rates can worsen the health of severely stenosed arteries by inducing flow instabilities and enhancing the spread and severity of recirculation zones. Understanding the flow characteristics and stress distribution in stenosed carotid arteries at different heart rates is crucial for prescribing appropriate exercise schedules for patients.
Article
Peripheral Vascular Disease
Sayuri Tokioka, Naoki Nakaya, Kumi Nakaya, Masato Takase, Mana Kogure, Rieko Hatanaka, Ippei Chiba, Ikumi Kanno, Kotaro Nochioka, Hirohito Metoki, Takahisa Murakami, Michihiro Satoh, Tomohiro Nakamura, Taku Obara, Yohei Hamanaka, Tomoko Kobayashi, Akira Uruno, Junichi Sugawara, Eiichi N. Kodama, Soichi Ogishima, Yoko Izumi, Nobuo Fuse, Shinichi Kuriyama, Ichiro Tsuji, Atsushi Hozawa
Summary: This study aimed to assess the impact of central blood pressure and carotid intima media thickness on the risk of hypertension in people with high normal blood pressure. The results showed that higher central blood pressure and thicker carotid intima media thickness at baseline were associated with the development of hypertension in individuals with high normal blood pressure.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2023)
Article
Peripheral Vascular Disease
Xiaoxiang Ma, Yue Zhuo, Yu Huang, Pengming He, Zhaoyi Huang, Li Jiang, Luyao Tong, Xiaoqin Yao, Xueping Wen, Xuemei Zhong, Shihan Yang, Changqiong Li, Yuping Liu, Zhixin Zhang
Summary: This study reveals that abnormal T-cell responses may play important roles in the progression of essential hypertension and its subclinical target organ damage. The TCR beta repertoires of patients with essential hypertension are significantly different, and are correlated with carotid plaque formation.
Article
Peripheral Vascular Disease
Antonios A. Argyris, Dimitrios Mouziouras, Stamatia Samara, Yi Zhang, Marios K. Georgakis, Jacques Blacher, Michel Safar, Petros P. Sfikakis, Athanase D. Protogerou
Summary: The study found that 24-hour aortic systolic blood pressure (aSBP) was superior in its association with indices of arterial damage compared to 24-hour brachial systolic blood pressure (bSBP). It also demonstrated better discriminatory ability in detecting carotid hypertrophy and carotid atheromatosis. Additionally, the association was more pronounced in individuals with higher SBP amplification variability.
Article
Peripheral Vascular Disease
De-Wei An, Iram Faqir Muhammad, Ming-Xuan Li, Yan Borne, Chang-Sheng Sheng, Margaretha Persson, Ren-Zhi Cai, Qian-Hui Guo, Ji-Guang Wang, Gunnar Engstrom, Yan Li, Peter M. Nilsson
Summary: The beat-to-beat variability of carotid-to-femoral pulse wave velocity (cf-PTT) was found to predict mortality and improve risk stratification in elderly individuals, particularly in terms of all-cause mortality and cardiovascular mortality. This could potentially serve as a novel risk indicator for elderly populations.
Article
Medicine, General & Internal
Genhuan Yang, Rong Zeng, Xitao Song, Changwei Liu, Leng Ni
Summary: The study demonstrates that Sophocarpine can effectively alleviate vascular intimal hyperplasia following balloon injury, potentially through its inhibitory effect on inflammation signals. This suggests the potential applicability of Sophocarpine in treating restenosis after balloon angioplasty.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Gabrielle Laloy-Borgna, Leo Puyo, Hidero Nishino, Michael Atlan, Stefan Catheline
Summary: The risk of cardiovascular events is associated with the elasticity of arteries, which can be estimated from the pulse wave velocity. However, current ultrasound imaging techniques lack accuracy and optical measurements on retinal arteries yield inconsistent results. This study presents the discovery of an antisymmetric pulse wave called the flexural pulse wave, observed for the first time. Optical system measurements on retinal arteries and veins show a velocity range of 1-10 millimeters per second. This wave mode has potential as a biomarker for blood vessel aging, and it can also be detected using ultrafast ultrasound imaging on larger carotid arteries.
Article
Mechanics
Muhamed Albadawi, Yasser Abuouf, Samir Elsagheer, Shinichi Ookawara, Mahmoud Ahmed
Summary: Carotid artery disease, characterized by narrowed arteries due to plaque buildup, can be investigated using hemodynamic parameters. A computational fluid dynamics approach based on patient-specific models can be effectively used to diagnose and predict carotid artery stenosis, indicating potential high-risk regions.
Article
Pediatrics
Ashraf Sayed Kamel, Mohamed Mohamed Ezzat AlGhawass, Muhammad Adel Sayed, Sara Aly Roby
Summary: A study found that children with nephrotic syndrome have significantly higher carotid intima media thickness compared to healthy controls, and it is positively correlated with disease duration, number of relapses, and body mass index. CIMT is also significantly higher in patients receiving non-steroid immunosuppressive therapy compared to those receiving steroids alone.
ITALIAN JOURNAL OF PEDIATRICS
(2022)
Review
Cardiac & Cardiovascular Systems
Orsolya Anna Simon, Aniko Gorbe, Peter Hegyi, Lajos Szako, Eduard Ostarijas, Fanni Dembrovszky, Szabolcs Kiss, Laszlo Czopf, Balint Eross, Imre Szabo
Summary: This study found an association between H. pylori infection and increased carotid intima-media thickness through a systematic review and meta-analysis.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Clarissa J. Wiertsema, Vincent W. V. Jaddoe, Annemarie G. M. G. J. Mulders, Romy Gaillard
Summary: Gestational hypertension and higher gestational blood pressure are associated with higher offspring blood pressure and lower carotid distensibility. However, preeclampsia is not associated with offspring vascular outcomes. These associations are more likely driven by genetic predisposition and shared lifestyle rather than by a direct intrauterine effect.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Biochemistry & Molecular Biology
Xingmeng Zhu, Yong Fan, Jie Sheng, Ling Gu, Qi Tao, Rui Huang, Kaiyong Liu, Linsheng Yang, Guimei Chen, Hongjuan Cao, Kaichun Li, Fangbiao Tao, Sufang Wang
Summary: The study found that the combined exposure of aluminum, cobalt, and vanadium was a protective factor against dyslipidemia in the elderly Chinese population, while the combined exposure of cadmium, strontium, and lead was a risk factor for dyslipidemia.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Monica Simina Mihuta, Corina Paul, Andreea Borlea, Cristina Mihaela Roi, Oana-Alexandra Velea-Barta, Ioana Mozos, Dana Stoian
Summary: Obese children have a higher risk of cardiovascular diseases. Measuring vascular biomarkers can be helpful in assessing arterial stiffness, subclinical atherosclerosis, and hypertension in these children. The study found that all vascular biomarkers were increased in obese children compared to normal-weight children. Various cut-off values for different age groups can be used to detect obesity-related vascular damage. Waist circumference and waist-to-height ratio showed correlation with all vascular parameters. Insulin resistance played a role in predicting vascular damage, except for carotid intima-media thickness. Detection of acanthosis nigricans can be predicted by specific cut-off values. Elevated levels of certain markers and low levels of HDL-c and vitamin D were correlated with higher arterial stiffness and CIMT values. CIMT and markers of arterial stiffness are useful in the early detection of vascular damage in obese children.
