Role of tumor microenvironment in the pathobiology of ovarian cancer: Insights and therapeutic opportunities
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Title
Role of tumor microenvironment in the pathobiology of ovarian cancer: Insights and therapeutic opportunities
Authors
Keywords
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Journal
Cancer Medicine
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-08-23
DOI
10.1002/cam4.1741
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Note: Only part of the references are listed.- SPP1 promotes ovarian cancer progression via Integrin β1/FAK/Akt signaling pathway
- (2018) Biao zeng et al. OncoTargets and Therapy
- Changes in regulatory T cells in patients with ovarian cancer undergoing surgery: Preliminary results
- (2017) Meng Wu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance
- (2017) Cecilia S. Leung et al. JOURNAL OF CLINICAL INVESTIGATION
- Mesothelial-to-mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer
- (2017) Angela Rynne-Vidal et al. JOURNAL OF PATHOLOGY
- The emerging roles and therapeutic potential of exosomes in epithelial ovarian cancer
- (2017) Xiaoduan Li et al. Molecular Cancer
- Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer
- (2017) et al. JAMA Oncology
- Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer
- (2017) Yuliya Klymenko et al. Cancers
- The Unique Molecular and Cellular Microenvironment of Ovarian Cancer
- (2017) Thomas Worzfeld et al. Frontiers in Oncology
- Functional prediction of long non-coding RNAs in ovarian cancer-associated fibroblasts indicate a potential role in metastasis
- (2017) Fatemeh Vafaee et al. Scientific Reports
- LPA receptor 1 mediates LPA-induced ovarian cancer metastasis: an in vitro and in vivo study
- (2016) Xuechen Yu et al. BMC CANCER
- Ascites modulates cancer cell behavior, contributing to tumor heterogeneity in ovarian cancer
- (2016) Soochi Kim et al. CANCER SCIENCE
- Notch and TGFβ form a positive regulatory loop and regulate EMT in epithelial ovarian cancer cells
- (2016) Jiesi Zhou et al. CELLULAR SIGNALLING
- Adipose Tissue Hypoxia, Inflammation, and Fibrosis in Obese Insulin-Sensitive and Obese Insulin-Resistant Subjects
- (2016) Helen M. Lawler et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Interaction between Treg cells and tumor-associated macrophages in the tumor microenvironment of epithelial ovarian cancer
- (2016) Qinyi Zhu et al. ONCOLOGY REPORTS
- Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
- (2016) Solene M. Evrard et al. Nature Communications
- Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2, Src, and HIF1α signaling nexus
- (2016) Ji Hee Ha et al. Oncotarget
- Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment
- (2016) Elena Zoico et al. Oncotarget
- Inflammation-regulating factors in ascites as predictive biomarkers of drug resistance and progression-free survival in serous epithelial ovarian cancers
- (2015) Denis Lane et al. BMC CANCER
- Infiltration of dendritic cells and T lymphocytes predicts favorable outcome in epithelial ovarian cancer
- (2015) Z Zhang et al. CANCER GENE THERAPY
- Analysis of CD8+ Treg cells in patients with ovarian cancer: a possible mechanism for immune impairment
- (2015) Shuping Zhang et al. Cellular & Molecular Immunology
- TGFβ signaling regulates epithelial–mesenchymal plasticity in ovarian cancer ascites-derived spheroids
- (2015) Samah Rafehi et al. ENDOCRINE-RELATED CANCER
- Risk of Ovarian Cancer Relapse Score
- (2015) Ivana Rizzuto et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Clinical significance of plasma lysophosphatidic acid levels in the differential diagnosis of ovarian cancer
- (2015) Yun-Jie Zhang et al. Journal of Cancer Research and Therapeutics
- Ovary and fimbrial stem cells: biology, niche and cancer origins
- (2015) Annie Ng et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma
- (2015) Pi-Lin Sung et al. Oncotarget
- Decitabine Enhances Lymphocyte Migration and Function and Synergizes with CTLA-4 Blockade in a Murine Ovarian Cancer Model
- (2015) L. Wang et al. Cancer Immunology Research
- CTLA-4 Blockade Synergizes Therapeutically with PARP Inhibition in BRCA1-Deficient Ovarian Cancer
- (2015) T. Higuchi et al. Cancer Immunology Research
- The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis
- (2015) Angela Rynne-Vidal et al. Cancers
- SPARC Ameliorates Ovarian Cancer-Associated Inflammation
- (2015) Neveen A. Said et al. NEOPLASIA
- Differential Roles of uPAR in Peritoneal Ovarian Carcinomatosis
- (2015) Nada N. Al-Hassan et al. NEOPLASIA
- Anti-vascular therapies in ovarian cancer: moving beyond anti-VEGF approaches
- (2014) Hyun-Jin Choi et al. CANCER AND METASTASIS REVIEWS
- Indoleamine 2,3-dioxygenase promotes peritoneal metastasis of ovarian cancer by inducing an immunosuppressive environment
- (2014) Yuko Tanizaki et al. CANCER SCIENCE
- New insights into cancer immunoediting and its three component phases—elimination, equilibrium and escape
- (2014) Deepak Mittal et al. CURRENT OPINION IN IMMUNOLOGY
- The dual PI3K/mTOR inhibitor NVP-BEZ235 prevents epithelial–mesenchymal transition induced by hypoxia and TGF-β1
- (2014) Guanyu Lin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The non-canonical Wnt ligand, Wnt5a, is upregulated and associated with epithelial to mesenchymal transition in epithelial ovarian cancer
- (2014) C.E. Ford et al. GYNECOLOGIC ONCOLOGY
- Hypoxia promotes vasculogenic mimicry formation by inducing epithelial–mesenchymal transition in ovarian carcinoma
- (2014) Jing Du et al. GYNECOLOGIC ONCOLOGY
- Mesenchymal gene program–expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance
- (2014) Rachel A. Davidowitz et al. JOURNAL OF CLINICAL INVESTIGATION
- Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion
- (2014) Hilary A. Kenny et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors
- (2014) Gregory T Motz et al. NATURE MEDICINE
- Reactive oxygen species promote ovarian cancer progression via the HIF-1α/LOX/E-cadherin pathway
- (2014) YU WANG et al. ONCOLOGY REPORTS
- T-Cell and NK-Cell Infiltration into Solid Tumors: A Key Limiting Factor for Efficacious Cancer Immunotherapy
- (2014) I. Melero et al. Cancer Discovery
- Milky Spots Promote Ovarian Cancer Metastatic Colonization of Peritoneal Adipose in Experimental Models
- (2013) Robert Clark et al. AMERICAN JOURNAL OF PATHOLOGY
- TGF- Modulates Ovarian Cancer Invasion by Upregulating CAF-Derived Versican in the Tumor Microenvironment
- (2013) T.-L. Yeung et al. CANCER RESEARCH
- Adipocyte-Derived Fibroblasts Promote Tumor Progression and Contribute to the Desmoplastic Reaction in Breast Cancer
- (2013) L. Bochet et al. CANCER RESEARCH
- A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
- (2013) C. L.-L. Chiang et al. CLINICAL CANCER RESEARCH
- Altered expression of inflammation-associated genes in oviductal cells following follicular fluid exposure: Implications for ovarian carcinogenesis
- (2013) Angela Lau et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Myeloid-Derived Suppressor Cells Enhance Stemness of Cancer Cells by Inducing MicroRNA101 and Suppressing the Corepressor CtBP2
- (2013) Tracy X. Cui et al. IMMUNITY
- The Stem-Cell Profile of Ovarian Surface Epithelium is Reproduced in the Oviductal Fimbriae, with Increased Stem-Cell Marker Density in Distal Parts of the Fimbriae
- (2013) Nelly Auersperg INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
- Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis
- (2013) Pilar Sandoval et al. JOURNAL OF PATHOLOGY
- A Phase I vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer
- (2013) Lana E Kandalaft et al. Journal of Translational Medicine
- The Role of Nuclear β-Catenin Accumulation in the Twist2-Induced Ovarian Cancer EMT
- (2013) Yubin Mao et al. PLoS One
- ‘Cancer associated fibroblasts’ – more than meets the eye
- (2013) Shalom Madar et al. TRENDS IN MOLECULAR MEDICINE
- An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
- (2013) R Y-J Huang et al. Cell Death & Disease
- Tumor Endothelial Cells
- (2013) A. C. Dudley Cold Spring Harbor Perspectives in Medicine
- Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research
- (2013) Nuzhat Ahmed et al. Frontiers in Oncology
- Does tumour biology determine surgical success in the treatment of epithelial ovarian cancer? A systematic literature review
- (2012) J Borley et al. BRITISH JOURNAL OF CANCER
- Fibrillar Type I Collagen Matrices Enhance Metastasis/Invasion of Ovarian Epithelial Cancer Via β1 Integrin and PTEN Signals
- (2012) Yufei Shen et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Epithelial–Mesenchymal Transition in Ovarian Carcinoma
- (2012) Ben Davidson et al. Frontiers in Oncology
- Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion
- (2011) Yuan Zhang et al. CANCER LETTERS
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- PGE2-Induced CXCL12 Production and CXCR4 Expression Controls the Accumulation of Human MDSCs in Ovarian Cancer Environment
- (2011) N. Obermajer et al. CANCER RESEARCH
- Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness
- (2011) J. Cai et al. CARCINOGENESIS
- Immune Response in Ovarian Cancer: How Is the Immune System Involved in Prognosis and Therapy: Potential for Treatment Utilization
- (2011) Nikos G. Gavalas et al. Clinical & Developmental Immunology
- Prognostic significance of tumor-infiltrating T cells in ovarian cancer: A meta-analysis
- (2011) Wei-Ting Hwang et al. GYNECOLOGIC ONCOLOGY
- Immunity and immune suppression in human ovarian cancer
- (2011) Claudia C Preston et al. Immunotherapy
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- Ovarian Cancer Spheroids Use Myosin-Generated Force to Clear the Mesothelium
- (2011) Marcin P. Iwanicki et al. Cancer Discovery
- Ovarian Cancer Development and Metastasis
- (2010) Ernst Lengyel AMERICAN JOURNAL OF PATHOLOGY
- Lysophosphatidic acid (LPA)—a perspective marker in ovarian cancer
- (2010) Iva Sedláková et al. TUMOR BIOLOGY
- Vascular Cell Adhesion Molecule-1 Is a Regulator of Ovarian Cancer Peritoneal Metastasis
- (2009) Jill K. Slack-Davis et al. CANCER RESEARCH
- Lysophosphatidic Acid-Induced Transcriptional Profile Represents Serous Epithelial Ovarian Carcinoma and Worsened Prognosis
- (2009) Mandi M. Murph et al. PLoS One
- Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via 5-Integrin, which Is a Therapeutic Target
- (2008) K. Sawada et al. CANCER RESEARCH
- The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin
- (2008) Hilary A. Kenny et al. JOURNAL OF CLINICAL INVESTIGATION
- “Re-educating” tumor-associated macrophages by targeting NF-κB
- (2008) Thorsten Hagemann et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NK cells and cancer immunosurveillance
- (2008) I Waldhauer et al. ONCOGENE
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