Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway

Towards carborane-functionalised structures for the treatment of brain cancer

(2018) Gianpiero Calabrese et al.   DRUG DISCOVERY TODAY

Redox regulation of the tumor suppressor PTEN by the thioredoxin system and cumene hydroperoxide

(2017) Seong-Jeong Han et al.   FREE RADICAL BIOLOGY AND MEDICINE

Matrine increases the inhibitory effects of afatinib on H1975 cells via the IL-6/JAK1/STAT3 signaling pathway

(2017) Shui-Fang Chen et al.   Molecular Medicine Reports

Targeting nitric oxide and NMDA receptor-associated pathways in treatment of high grade glial tumors. Hypotheses for nitro-memantine and nitrones

(2017) Meric A. Altinoz et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Matrine inhibits the metastatic properties of human cervical cancer cells via downregulating the p38 signaling pathway

(2017) Xiaoling Wu et al.   ONCOLOGY REPORTS

Berberine induces oxidative DNA damage and impairs homologous recombination repair in ovarian cancer cells to confer increased sensitivity to PARP inhibition

(2017) Dong Hou et al.   Cell Death & Disease

Matrine inhibits cell proliferation and induces apoptosis of human rhabdomyosarcoma cells via downregulation of the extracellular signal-regulated kinase pathway

(2017) Penghui Yan et al.   Oncology Letters

SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation

(2016) Ganye Zhao et al.   Aging-US

Matrine Attenuates COX-2 and ICAM-1 Expressions in Human Lung Epithelial Cells and Prevents Acute Lung Injury in LPS-Induced Mice

(2016) Chian-Jiun Liou et al.   MEDIATORS OF INFLAMMATION

PIM-1 modulates cellular senescence and links IL-6 signaling to heterochromatin formation

(2015) Bo Jin et al.   AGING CELL

Implementing a Class of Permutation Tests: ThecoinPackage

(2015) Torsten Hothorn et al.   Journal of Statistical Software

High-grade glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2014) R. Stupp et al.   ANNALS OF ONCOLOGY

Molecular Genetics of Gliomas

(2014) Christina L. Appin et al.   CANCER JOURNAL

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Natural Products: Promising Resources for Cancer Drug Discovery

(2012) Susmita Mondal et al.   Anti-Cancer Agents in Medicinal Chemistry

Matrine Inhibits Breast Cancer Growth ViamiR-21/PTEN/AktPathway in MCF-7 Cells

(2012) Lin-Qiang Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Primary brain tumours in adults

(2012) Damien Ricard et al.   LANCET

Baicalein inhibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo

(2012) Naveenkumar Chandrashekar et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

IGF-1 induced HIF-1α-TLR9 cross talk regulates inflammatory responses in glioma

(2011) Sanchari Sinha et al.   CELLULAR SIGNALLING

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE