Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction

Uncoupling Protein-4 (UCP4) Increases ATP Supply by Interacting with Mitochondrial Complex II in Neuroblastoma Cells

(2012) Philip Wing-Lok Ho et al.   PLoS One

Age and sex-related changes in rat brain mitochondrial oxidative status

(2011) Rocío Guevara et al.   EXPERIMENTAL GERONTOLOGY

UCP4 overexpression improves fatty acid oxidation and insulin sensitivity in L6 myocytes

(2011) Chun-Lin Gao et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Caenorhabditis elegansUCP4 Protein Controls Complex II-mediated Oxidative Phosphorylation through Succinate Transport

(2011) Matthew Pfeiffer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of mitochondrial uncoupling protein 4 in rat inner ear

(2011) Alina Smorodchenko et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain

(2011) William T. Senapedis et al.   MOLECULAR BIOLOGY OF THE CELL

Regulated expression of neuronal SIRT1 and related genes by aging and neuronal β2-containing nicotinic cholinergic receptors

(2011) P.-S. Huang et al.   NEUROSCIENCE

The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease

(2011) D.J. Surmeier et al.   NEUROSCIENCE

Mitochondrial UCP4 and bcl-2 expression in imprints of breast carcinomas: Relationship with DNA ploidy and classical prognostic factors

(2011) Maria Gonidi et al.   PATHOLOGY RESEARCH AND PRACTICE

Association of anUCP4(SLC25A27) haplotype with ultra-resistant schizophrenia

(2011) Fayçal Mouaffak et al.   PHARMACOGENOMICS

Association of the Sirtuin and Mitochondrial Uncoupling Protein Genes with Carotid Plaque

(2011) Chuanhui Dong et al.   PLoS One

A homozygous genetic variant of mitochondrial uncoupling protein 4 affects the occurrence of leukoaraiosis

(2010) Z. Szolnoki et al.   ACTA NEUROLOGICA SCANDINAVICA

Targeting Forkhead Box O1 from the Concept to Metabolic Diseases: Lessons from Mouse Models

(2010) Zhiyong Cheng et al.   ANTIOXIDANTS & REDOX SIGNALING

Enhancing T3 and cAMP responsive gene participation in the thermogenic regulation of fuel oxidation pathways

(2010) Karina Kores Dorsa et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Mitochondrial proton and electron leaks

(2010) Martin Jastroch et al.   Essays in Biochemistry

Transcriptional regulation of UCP4 by NF-κB and its role in mediating protection against MPP+ toxicity

(2010) Jessica Wing-Man Ho et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial UCP5 is neuroprotective by preserving mitochondrial membrane potential, ATP levels, and reducing oxidative stress in MPP+ and dopamine toxicity

(2010) Ken Hon-Hung Kwok et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased energy metabolism rescues glia-induced pathology in a Drosophila model of Huntington's disease

(2010) Marie-Thérèse Besson et al.   HUMAN MOLECULAR GENETICS

Truncation of PITX2 differentially affects its activity on physiological targets

(2010) M.-H. Quentien et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

CREB: a multifaceted regulator of neuronal plasticity and protection

(2010) Kensuke Sakamoto et al.   JOURNAL OF NEUROCHEMISTRY

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

(2010) Jaime N. Guzman et al.   NATURE

The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury

(2010) A Lanzillotta et al.   Cell Death & Disease

Superoxide Anion Regulates the Mitochondrial Free Ca2+ Through Uncoupling Proteins

(2009) Zhaofei Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Saturated fatty acids stimulate and insulin suppresses BMCP1 expression in bovine mammary epithelial cells

(2009) Tomo Yonezawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Comparative Study on Conformation and Ligand Binding of the Neuronal Uncoupling Proteins

(2009) Marina V. Ivanova et al.   BIOCHEMISTRY

Comparative analysis of uncoupling protein 4 distribution in various tissues under physiological conditions and during development

(2009) Alina Smorodchenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Hydrogen Peroxide Regulates the Mitochondrial Content of Uncoupling Protein 5 in Colon Cancer Cells

(2009) Francisca M. Santandreu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Estrogen down-regulates uncoupling proteins and increases oxidative stress in breast cancer

(2009) Jorge Sastre-Serra et al.   FREE RADICAL BIOLOGY AND MEDICINE

Absolute levels of transcripts for mitochondrial uncoupling proteins UCP2, UCP3, UCP4, and UCP5 show different patterns in rat and mice tissues

(2009) Lukáš Alán et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

(2009) J. N. Guzman et al.   JOURNAL OF NEUROSCIENCE

A Homozygous Genetic Variant of Mitochondrial Uncoupling Protein 4 Exerts Protection Against the Occurrence of Multiple Sclerosis

(2009) Zoltan Szolnoki et al.   NEUROMOLECULAR MEDICINE

The Brain Uncoupling Protein UCP4 Attenuates Mitochondrial Toxin-Induced Cell Death: Role of Extracellular Signal-Regulated Kinases in Bioenergetics Adaptation and Cell Survival

(2009) Zelan Wei et al.   NEUROTOXICITY RESEARCH

Sex-dependent differences in aged rat brain mitochondrial function and oxidative stress

(2008) Rocío Guevara et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial UCP4 attenuates MPP+- and dopamine-induced oxidative stress, mitochondrial depolarization, and ATP deficiency in neurons and is interlinked with UCP2 expression

(2008) Andrew Chi-Yuen Chu et al.   FREE RADICAL BIOLOGY AND MEDICINE

BMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production

(2003) Jeong Sook Kim-Han et al.   JOURNAL OF NEUROCHEMISTRY

ΔΨm-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

(2003) Tatyana V. Votyakova et al.   JOURNAL OF NEUROCHEMISTRY