Suppressive Effects of Plumbagin on Invasion and Migration of Breast Cancer Cells via the Inhibition of STAT3 Signaling and Down-regulation of Inflammatory Cytokine Expressions

STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma

(2012) Bing Tu et al.   CANCER LETTERS

Plumbagin Inhibits Breast Tumor Bone Metastasis and Osteolysis by Modulating the Tumor-Bone Microenvironment

(2012) Z. Li et al.   CURRENT MOLECULAR MEDICINE

The RhoA pathway mediates MMP-2 and MMP-9-independent invasive behavior in a triple-negative breast cancer cell line

(2012) Katerina D. Fagan-Solis et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Curcuminoids Block TGF-β Signaling in Human Breast Cancer Cells and Limit Osteolysis in a Murine Model of Breast Cancer Bone Metastasis

(2012) Laura E. Wright et al.   JOURNAL OF NATURAL PRODUCTS

High expression of CD147 and MMP-9 is correlated with poor prognosis of triple-negative breast cancer (TNBC) patients

(2012) Shu Zhao et al.   MEDICAL ONCOLOGY

Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression

(2011) Akihisa Fukuda et al.   CANCER CELL

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), isolated from Plumbago zeylanica, inhibits ultraviolet radiation-induced development of squamous cell carcinomas

(2011) J. M. Sand et al.   CARCINOGENESIS

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

(2011) Kanjoormana Manu et al.   Molecular Cancer

Plumbagin Inhibits Osteoclastogenesis and Reduces Human Breast Cancer-Induced Osteolytic Bone Metastasis in Mice through Suppression of RANKL Signaling

(2011) B. Sung et al.   MOLECULAR CANCER THERAPEUTICS

Notch, IL-1 and Leptin Crosstalk Outcome (NILCO) Is Critical for Leptin-Induced Proliferation, Migration and VEGF/VEGFR-2 Expression in Breast Cancer

(2011) Shanchun Guo et al.   PLoS One

Anti-inflammatory effects of plumbagin are mediated by inhibition of NF-kappaB activation in lymphocytes

(2009) Rahul Checker et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TGF-β signalling-related markers in cancer patients with bone metastasis

(2008) Jose Baselga et al.   BIOMARKERS

Plumbagin, a Medicinal Plant–Derived Naphthoquinone, Is a Novel Inhibitor of the Growth and Invasion of Hormone-Refractory Prostate Cancer

(2008) Moammir H. Aziz et al.   CANCER RESEARCH

Frequency and Risk Factors Associated With Osteonecrosis of the Jaw in Cancer Patients Treated With Intravenous Bisphosphonates

(2008) Ana O Hoff et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-κB and Bcl-2

(2008) Aamir Ahmad et al.   JOURNAL OF CELLULAR BIOCHEMISTRY