Methotrexate Inhibits NF-κB Activity Via Long Intergenic (Noncoding) RNA-p21 Induction

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

(2013) Tomer Cooks et al.   CANCER CELL

Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect

(2013) Fan Yang et al.   MOLECULAR CELL

Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining

(2013) V. Oksenych et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

LincRNA-p21 Suppresses Target mRNA Translation

(2012) Je-Hyun Yoon et al.   MOLECULAR CELL

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress

(2012) S. Liu et al.   NUCLEIC ACIDS RESEARCH

Increased sensitivity to apoptosis induced by methotrexate is mediated by JNK

(2011) Charles F. Spurlock et al.   ARTHRITIS AND RHEUMATISM

Methotrexate increases expression of cell cycle checkpoint genes via JNK activation

(2011) Charles F. Spurlock et al.   ARTHRITIS AND RHEUMATISM

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

(2011) Tiffany Hung et al.   NATURE GENETICS

Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation

(2011) Eric J. Gapud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis

(2010) Lan Shao et al.   EMBO Molecular Medicine

p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism

(2010) Prashanth Ak et al.   FASEB JOURNAL

The ATM Inhibitor KU-55933 Suppresses Cell Proliferation and Induces Apoptosis by Blocking Akt In Cancer Cells with Overactivated Akt

(2010) Y. Li et al.   MOLECULAR CANCER THERAPEUTICS

Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

(2010) Mitchell Guttman et al.   NATURE BIOTECHNOLOGY

Methotrexate—how does it really work?

(2010) Edwin S. L. Chan et al.   Nature Reviews Rheumatology

Pathologies Associated with the p53 Response

(2010) A. V. Gudkov et al.   Cold Spring Harbor Perspectives in Biology

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis

(2009) Lan Shao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

Telomerase insufficiency in rheumatoid arthritis

(2009) H. Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why do people with rheumatoid arthritis still die prematurely?

(2008) S E Gabriel   ANNALS OF THE RHEUMATIC DISEASES

An Integrated Approach for the Analysis of Biological Pathways using Mixed Models

(2008) Lily Wang et al.   PLoS Genetics