Bone- and Cartilage-Protective Effects of a Monoclonal Antibody Against Colony-Stimulating Factor 1 Receptor in Experimental Arthritis

A unique anti-CD115 monoclonal antibody which inhibits osteolysis and skews human monocyte differentiation from M2-polarized macrophages toward dendritic cells

(2013) Hélène Haegel et al.   mAbs

Therapeutic Effects of Anti-CD115 Monoclonal Antibody in Mouse Cancer Models through Dual Inhibition of Tumor-Associated Macrophages and Osteoclasts

(2013) Laetitia Fend et al.   PLoS One

Monoclonal antibodies against macrophage colony-stimulating factor diminish the number of circulating intermediate and nonclassical (CD14++CD16+/CD14+CD16++) monocytes in rheumatoid arthritis patient

(2012) M. Korkosz et al.   BLOOD

SB1578, a Novel Inhibitor of JAK2, FLT3, and c-Fms for the Treatment of Rheumatoid Arthritis

(2012) B. Madan et al.   JOURNAL OF IMMUNOLOGY

Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis

(2012) Seung-Jun Hwang et al.   ARTHRITIS RESEARCH & THERAPY

Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients

(2011) M Chemel et al.   ANNALS OF THE RHEUMATIC DISEASES

Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation

(2011) Jason C Lenzo et al.   IMMUNOLOGY AND CELL BIOLOGY

M-CSF Potently Augments RANKL-Induced Resorption Activation in Mature Human Osteoclasts

(2011) Jason M. Hodge et al.   PLoS One

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

(2010) K. P. A. MacDonald et al.   BLOOD

Association between colony-stimulating factor 1 receptor gene polymorphisms and asthma risk

(2010) Eun Kyong Shin et al.   HUMAN GENETICS

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis

(2010) Marc Baud'Huin et al.   JOURNAL OF PATHOLOGY

The multiple faces of autoimmune-mediated bone loss

(2010) Georg Schett et al.   Nature Reviews Endocrinology

c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis

(2010) Ricardo T Paniagua et al.   ARTHRITIS RESEARCH & THERAPY

Effects of the cFMS Kinase Inhibitor 5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in Normal and Arthritic Rats

(2008) J. G. Conway et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The orally-active and selective c-Fms tyrosine kinase inhibitor Ki20227 inhibits disease progression in a collagen-induced arthritis mouse model

(2007) Hiroaki Ohno et al.   EUROPEAN JOURNAL OF IMMUNOLOGY