Article
Rheumatology
Katharina Ziegeler, Virginie Kreutzinger, Fabian Proft, Denis Poddubnyy, Kay Geert A. Hermann, Torsten Diekhoff
Summary: This study found that patients with mechanical joint disease had the highest proportion of atypical joints, with females showing significantly higher proportions than males, and symptomatic joint disease males having significantly higher proportions of atypical joints compared to controls.
Article
Radiology, Nuclear Medicine & Medical Imaging
Suleyman Kasar, Mesut Ozturk, Ahmet Veysel Polat
Summary: The study found that T2 values of both active and inactive sacroiliac joint cartilages of SpA patients were increased, indicating T2 mapping may be used in the diagnosis of SpA.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maxime Pastor, Cedric Lukas, Sonia Ramos-Pascual, Mo Saffarini, William Wantz, Catherine Cyteval
Summary: This study compared sacroiliac joint (SIJ) lesions on MRI in women with and without axial spondyloarthritis (ax-SpA) and established an algorithm to determine whether such lesions are due to ax-SpA. Women with ax-SpA had more bone marrow edema, sclerosis, erosions, and ankylosis, but less osteophytes compared to women without ax-SpA. The new algorithm for MRI diagnosis of ax-SpA in women achieved higher accuracy.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yitong Li, Yan Xiong, Bowen Hou, Chanyuan Liu, Jingyi Wang, Weiyin Vivian Liu, Xiaoming Li
Summary: The study found that ZTE MRI outperformed routine T1-weighted MRI in depicting structural lesions of sacroiliac joints. Compared to T1 FSE, ZTE MRI showed higher diagnostic accuracy for bone erosions, sclerosis, and joint space changes in the sacroiliac joints, with reliability comparable to CT.
EUROPEAN RADIOLOGY
(2022)
Article
Clinical Neurology
Andy Ton, Kevin Mertz, Marc Abdou, Nicole Hang, Emily S. Mills, Raymond J. Hah, Ram K. Alluri, Jeffrey C. Wang
Summary: This study examines the utilization and demographic trends for sacroiliac joint (SIJ) fusions in the US. It found that the annual utilization of SIJ fusion has been increasing and is projected to continue to grow in the future. Establishing evidence-based guidelines and improving diagnostic strategies are crucial to support the growing use of SIJ fusion in clinical practice.
GLOBAL SPINE JOURNAL
(2023)
Editorial Material
Rheumatology
Simon Cadiou, Guillaume Coiffier, Stephane Jouneau, Patrick Jego, Aleth Perdriger, Nicolas Belhomme, Raphael Guillin, Pascal Guggenbuhl
Summary: Only 3 out of 217 patients with confirmed sarcoidosis were found to have sacroiliitis by CT, and 4 patients had SpA. Degenerative changes in the sacroiliac joints were present in 28.1% of patients and were associated with age, pregnancy, rural lifestyle, and specific bone abnormalities. Further studies are needed to explore the relationship between SpA and sarcoidosis.
RHEUMATOLOGY INTERNATIONAL
(2022)
Review
Medicine, General & Internal
Brian Fiani, Manraj Sekhon, Thao Doan, Brianne Bowers, Claudia Covarrubias, Michaela Barthelmass, Frank De Stefano, Athanasios Kondilis
Summary: Pelvic girdle pain (PGP) affects nearly half of all pregnant women, with SIJ dysfunction caused by various biomechanical mechanisms. Studies show that female patients with PGP continue to experience pain postpartum, with improvement in pain scores seen in those treated with SIJ fusion compared to non-operatively treated patients. Further research is needed to optimize surgical outcomes for postpartum women with SIJ dysfunction.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lieve Morbee, Elke Vereecke, Frederiek Laloo, Min Chen, Nele Herregods, Lennart B. O. Jans
Summary: The purpose of this study was to determine the prevalence of incidental findings on sacroiliac joint MRI and the added value of MRI-based synthetic CT for detecting and evaluating these findings. The results showed that incidental findings were more common than sacroiliitis on sacroiliac joint MRI, and more than half of these findings were only visible on synthetic CT.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Clinical Neurology
Noojan Kazemi, Muhammad Abu-Rmaileh, Sidhant Dalal, Matthew Helton, Jerry Walters
Summary: The study investigated a novel technique of performing minimally invasive sacroiliac joint fusions in the lateral decubitus position, which showed promising surgical parameters and feasibility indicators, with 93% of patients reporting improvement in postoperative pain. A future study comparing traditional perioperative parameters with surgical ergonomics is recommended for further evaluation.
WORLD NEUROSURGERY
(2021)
Article
Orthopedics
Samina Yasin, Outi Makitie, Sadaf Naz
Summary: Loss or gain of function variants in Filamin B (FLNB) can cause recessive or dominant skeletal disorders. Spondylocarpotarsal synostosis syndrome (SCT) is a rare autosomal recessive disorder characterized by short stature and bone fusion. A novel homozygous pathogenic variant in FLNB was identified in a family with skeletal malformations, short stature, and vertebral deformities. This report highlights the importance of assessing the heights of carriers of FLNB recessive variants in relation to idiopathic short stature.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Clinical Neurology
Jeffrey E. Wessell, Brian F. Saway, Laura Wolgamott, Christopher Litts, John A. Glaser, Sunil J. Patel, Stephen P. Kalhorn
Summary: This study investigates the impact of patient factors and sacroiliac joint anatomical structure on SIJ fusion outcomes. The results suggest that variant joint anatomy is more prevalent in pathological SIJ and there may be differences in surgical outcomes based on SIJ anatomy. Larger sample sizes are needed for future research to confirm these differences.
WORLD NEUROSURGERY
(2022)
Article
Anesthesiology
Nagy Mekhail, Youssef Saweris, Diana Sue Mehanny, Natalya Makarova, Maged Guirguis, Shrif Costandi
Summary: The study aimed to evaluate the sensitivity and specificity of clinical tests for diagnosing SIJ pain and determine their predictive value. Results showed that the combination of Patrick and Mekhail tests demonstrated the best accuracy, with an increase in sensitivity but a decrease in specificity when adding simultaneous tests.
Review
Physiology
Clement Prati, Thierry Lequerre, Benoit Le Goff, Bernard Cortet, Hechmi Toumi, Anne Tournadre, Hubert Marotte, Eric Lespessailles
Summary: A detailed anatomical description of the sacroiliac joint is crucial for understanding spondyloarthropathy, as sacroiliitis is its earliest and most common sign. Additionally, understanding the histopathology and immunological mechanisms of sacroiliac entheses is essential for comprehending the disease causation. This review focuses on the anatomical, histological, and immunohistological observations related to the development of sacroiliitis and discusses the sequencing of enthesitis, synovitis, and subchondral bone changes in spondyloarthropathy.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Immunology
Yimeng Zhang, Zikang Guo, Lisong Wang, Ying Zhan, Jin Qu, Xinwei Lei
Summary: Fat metaplasia in axial spondyloarthritis (axSpA) patients predicts backfill progression, suggesting an important mechanism in this disease.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Anesthesiology
Rajesh Naidu Janapala, Emilija Knezevic, Nebojsa Nick Knezevic, Rachana Pasupuleti, Mahendra R. Sanapati, Alan D. Kaye, Vidyasagar Pampati, Laxmaiah Manchikanti
Summary: The present systematic review and meta-analysis provide evidence that intraarticular injections in the sacroiliac joint are a fair therapeutic option for managing low back pain of sacroiliac joint origin. However, further studies are needed to confirm these findings and address the limitations identified.
Review
Clinical Neurology
Julia Vavken, Patrick Vavken, Alexander Mameghani, Carlo Camathias, Stefan Schaeren
EUROPEAN SPINE JOURNAL
(2016)
Article
Clinical Neurology
Julia Vavken, Alexander Mameghani, Patrick Vavken, Stefan Schaeren
EUROPEAN SPINE JOURNAL
(2016)
Article
Radiology, Nuclear Medicine & Medical Imaging
Malwina Kaniewska, Johannes Maria de Beus, Frank Ahlhelm, Alexander Mameghani, Karim Eid, Rahel A. Kubik-Huch, Suzanne E. Anderson
Article
Orthopedics
C. W. Mueller, T. Goesling, A. Mameghani, R. Stier, M. Klein, T. Huefner, C. Krettek
Letter
Emergency Medicine
A. Mameghani
Article
Clinical Neurology
Lukas Urbanschitz, Sascha Merat, Susanne Bensler, Christopher G. Lenz, Alexander T. Mameghani, Karim Eid
Summary: This study found that as cervical disc degeneration progresses, the distance between surgical landmarks and the vertebral artery decreases, increasing the risk of vertebral artery injury. Surgeons should be aware of this loss of distance when dealing with high-grade cervical disc degeneration.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Review
Clinical Neurology
Julia Vavken, Patrick Vavken, Alexander Mameghani, Stefan Schaeren
GLOBAL SPINE JOURNAL
(2016)
Article
Urology & Nephrology
J Galle, A Mameghani, SS Bolz, S Gambaryan, M Görg, T Quaschning, U Raff, H Barth, S Seibold, C Wanner, U Pohl
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2003)
Article
Pharmacology & Pharmacy
C Ibarra-Alvarado, J Galle, VO Melichar, A Mameghani, HHHW Schmidt
MOLECULAR PHARMACOLOGY
(2002)