Lithium Protects Against Cartilage Degradation in Osteoarthritis

Annexin A6 Interacts With p65 and Stimulates NF-κB Activity and Catabolic Events in Articular Chondrocytes

(2013) Kirk A. Campbell et al.   ARTHRITIS AND RHEUMATISM

A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes

(2012) Bin Ma et al.   ARTHRITIS AND RHEUMATISM

Intracellular Modulation of Signaling Pathways by Annexin A6 Regulates Terminal Differentiation of Chondrocytes

(2012) Takeshi Minashima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased inflammatory cytokine expression in the vastus lateralis of patients with knee osteoarthritis

(2011) Itamar Levinger et al.   ARTHRITIS AND RHEUMATISM

Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes

(2011) Nahid Akhtar et al.   BMC Complementary and Alternative Medicine

Prolyl Oligopeptidase, Inositol Phosphate Signalling and Lithium Sensitivity

(2011) Adrian J. Harwood   CNS & Neurological Disorders-Drug Targets

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

IL-1  and TNF -initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis

(2011) T. Mori et al.   INTERNATIONAL IMMUNOLOGY

Interleukin-6 Synthesis in Human Chondrocytes Is Regulated via the Antagonistic Actions of Prostaglandin (PG)E2 and 15-deoxy-Δ12,14-PGJ2

(2011) Pu Wang et al.   PLoS One

Advanced glycation end products cause collagen II reduction by activating Janus kinase/signal transducer and activator of transcription 3 pathway in porcine chondrocytes

(2011) C.-Y. Huang et al.   RHEUMATOLOGY

Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation: MAPK phosphatase 1 as a novel target for antirheumatic drugs

(2010) Riina Nieminen et al.   ARTHRITIS AND RHEUMATISM

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Novel Insights into Lithium’s Mechanism of Action: Neurotrophic and Neuroprotective Effects

(2010) Jorge A. Quiroz et al.   NEUROPSYCHOBIOLOGY

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Lithium protects cartilage from cytokine-mediated degradation by reducing collagen-degrading MMP production via inhibition of the P38 mitogen-activated protein kinase pathway

(2010) Wang Hui et al.   RHEUMATOLOGY

Intra-articular drug delivery systems for the treatment of rheumatic diseases: A review of the factors influencing their performance

(2009) N. Butoescu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease

(2009) Ian D Welch et al.   ARTHRITIS RESEARCH & THERAPY

WNT signaling in osteoarthritis and osteoporosis: What is the biological significance for the clinician?

(2009) Liesbet Lodewyckx et al.   Current Rheumatology Reports

Reduced limb length and worsened osteoarthritis in adult mice after genetic inhibition of p38 MAP kinase activity in cartilage

(2008) Surena Namdari et al.   ARTHRITIS AND RHEUMATISM

Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

(2008) Mei Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wnt–β-catenin signaling in the pathogenesis of osteoarthritis

(2008) Maripat Corr   Nature clinical practice. Rheumatology