Estrogen Receptor α Regulates Tripartite Motif-Containing Protein 21 Expression, Contributing to Dysregulated Cytokine Production in Systemic Lupus Erythematosus

17 -Estradiol Alters the Activity of Conventional and IFN-Producing Killer Dendritic Cells

(2014) M. C. Siracusa et al.   JOURNAL OF IMMUNOLOGY

The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN-  Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3

(2014) R. Higgs et al.   JOURNAL OF IMMUNOLOGY

Estradiol differentially regulates calreticulin: a potential link with abnormal T cell function in systemic lupus erythematosus?

(2013) JM Ward et al.   LUPUS

Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21

(2013) William A McEwan et al.   NATURE IMMUNOLOGY

B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus-Prone Mice

(2012) S.-H. Hwang et al.   JOURNAL OF IMMUNOLOGY

Murine BAFF expression is up-regulated by estrogen and interferons: Implications for sex bias in the development of autoimmunity

(2012) Ravichandran Panchanathan et al.   MOLECULAR IMMUNOLOGY

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(2012) Vaishali Moulton et al.   MOLECULAR MEDICINE

The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA

(2012) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

Enhanced interferon regulatory factor 3 binding to the interleukin-23p19 promoter correlates with enhanced interleukin-23 expression in systemic lupus erythematosus

(2011) Siobhán Smith et al.   ARTHRITIS AND RHEUMATISM

Autoantibodies to estrogen receptor α interfere with T lymphocyte homeostasis and are associated with disease activity in systemic lupus erythematosus

(2011) Tania Colasanti et al.   ARTHRITIS AND RHEUMATISM

Oestrogen is a potent disease accelerator in SLE-prone MRL lpr/lpr mice

(2010) H. CARLSTEN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Unexplained Female Predominance of Systemic Lupus Erythematosus: Clues from Genetic and Cytokine Studies

(2010) Corinna E. Weckerle et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors

(2010) Rowan Higgs et al.   PLoS One

Gender-dependent Expression of Murine Irf5 Gene: Implications for Sex Bias in Autoimmunity

(2010) H. Shen et al.   Journal of Molecular Cell Biology

Polyreactive autoantibodies in systemic lupus erythematosus have pathogenic potential

(2009) Jie Zhang et al.   JOURNAL OF AUTOIMMUNITY

Vicious circle: systemic autoreactivity in Ro52/TRIM21-deficient mice: Figure 1.

(2009) Silvia Bolland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway

(2009) Alexander Espinosa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Sequestosome 1/p62 Attenuates Cytokine Gene Expression in Activated Macrophages by Inhibiting IFN Regulatory Factor 8 and TNF Receptor-Associated Factor 6/NF- B Activity

(2009) J. Y. Kim et al.   JOURNAL OF IMMUNOLOGY

Female and Male Sex Hormones Differentially Regulate Expression of Ifi202, an Interferon-Inducible Lupus Susceptibility Gene within the Nba2 Interval

(2009) R. Panchanathan et al.   JOURNAL OF IMMUNOLOGY

The Cyclic AMP Response Element Modulator   Suppresses CD86 Expression and APC Function

(2009) M. Ahlmann et al.   JOURNAL OF IMMUNOLOGY

17β-Estradiol Enhances the Response of Plasmacytoid Dendritic Cell to CpG

(2009) Xiaoxi Li et al.   PLoS One

Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse

(2008) John L. Svenson et al.   CLINICAL IMMUNOLOGY

TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved

(2008) A. H. Keeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA