Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules

Restoration of Adenosine Deaminase-Deficient Human Thymocyte Development In Vitro by Inhibition of Deoxynucleoside Kinases

(2014) M. L. Joachims et al.   JOURNAL OF IMMUNOLOGY

Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease

(2013) Tingting Weng et al.   FASEB JOURNAL

Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography

(2013) Jennifer M. Murphy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress

(2012) Wayne R. Austin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Post-Translational Phosphorylation of Serine 74 of Human Deoxycytidine Kinase Favors the Enzyme Adopting the Open Conformation Making It Competent for Nucleoside Binding and Release

(2011) Saugata Hazra et al.   BIOCHEMISTRY

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization

(2011) James Wesley Fairman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Requirement for deoxycytidine kinase in T and B lymphocyte development

(2010) G. Toy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors

(2009) Theodore C. Jessop et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase

(2009) James E. Tarver et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Elucidation of Different Binding Modes of Purine Nucleosides to Human Deoxycytidine Kinase

(2008) Elisabetta Sabini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural Basis for Substrate Promiscuity of dCK

(2008) Elisabetta Sabini et al.   JOURNAL OF MOLECULAR BIOLOGY

The intracellular activation of lamivudine (3TC) and determination of 2′-deoxycytidine-5′-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells

(2003) Stephen Kewn et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY