Ink4-Arf locus in cancer and aging

Expression of p16INK4a prevents cancer and promotes aging in lymphocytes

(2011) Y. Liu et al.   BLOOD

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells

(2011) Faiyaz Notta et al.   NATURE

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Linking functional decline of telomeres, mitochondria and stem cells during ageing

(2010) Ergün Sahin et al.   NATURE

Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

(2010) Axel Visel et al.   NATURE

Mechanisms of Stem Cell Self-Renewal

(2009) He Shenghui et al.   Annual Review of Cell and Developmental Biology

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Bmi1 regulates mitochondrial function and the DNA damage response pathway

(2009) Jie Liu et al.   NATURE

INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis

(2009) Yan Liu et al.   PLoS One

Small DNA tumor viruses: Large contributors to biomedical sciences

(2009) Peter M. Howley et al.   VIROLOGY

Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development

(2008) Ruprecht Wiedemeyer et al.   CANCER CELL

Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL

(2008) C. G. Mullighan et al.   GENES & DEVELOPMENT

Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf

(2008) R. A.J. Signer et al.   GENES & DEVELOPMENT

Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors

(2008) Omobolaji O. Akala et al.   NATURE

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE