Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation

The turn formation at positions 22 and 23 in the 42-mer amyloid β peptide: The emerging role in the pathogenesis of Alzheimer's disease

(2015) Kazuma Murakami et al.   Geriatrics & Gerontology International

Structural dynamics of the ΔE22 (Osaka) familial Alzheimer’s disease-linked amyloid β-protein

(2011) Mohammed Inayathullah et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Clinical Course of Patients with Familial Early-Onset Alzheimer’s Disease Potentially Lacking Senile Plaques Bearing the E693Δ Mutation in Amyloid Precursor Protein

(2011) Hiroyuki Shimada et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

The Osaka FAD Mutation E22Δ Leads to the Formation of a Previously Unknown Type of Amyloid β Fibrils and Modulates Aβ Neurotoxicity

(2011) Oxana Yu. Ovchinnikova et al.   JOURNAL OF MOLECULAR BIOLOGY

Intraneuronal APP, Not Free A  Peptides in 3xTg-AD Mice: Implications for Tau versus A -Mediated Alzheimer Neurodegeneration

(2011) M. J. Winton et al.   JOURNAL OF NEUROSCIENCE

Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo

(2011) Tomohiro Umeda et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Intracellular Aβ-oligomers and early inflammation in a model of Alzheimer's disease

(2011) Maria Teresa Ferretti et al.   NEUROBIOLOGY OF AGING

Monoclonal Antibody Against the Turn of the 42-Residue Amyloid β-Protein at Positions 22 and 23

(2010) Kazuma Murakami et al.   ACS Chemical Neuroscience

Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

(2010) Gunnar K. Gouras et al.   ACTA NEUROPATHOLOGICA

Hereditary Cerebral Hemorrhage With Amyloidosis Associated With the E693K Mutation of APP

(2010) Orso Bugiani et al.   ARCHIVES OF NEUROLOGY

Cerebral amyloid angiopathy: pathogenetic mechanisms and link to dense amyloid plaques

(2010) S. Kumar-Singh   GENES BRAIN AND BEHAVIOR

A Mouse Model of Amyloid   Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo

(2010) T. Tomiyama et al.   JOURNAL OF NEUROSCIENCE

The E693Δ Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid β Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Cells

(2009) Kazuchika Nishitsuji et al.   AMERICAN JOURNAL OF PATHOLOGY

Spatial memory: Theoretical basis and comparative review on experimental methods in rodents

(2009) Carrillo-Mora Paul et al.   BEHAVIOURAL BRAIN RESEARCH

Hereditary and Sporadic Forms of Aβ-Cerebrovascular Amyloidosis and Relevant Transgenic Mouse Models

(2009) Samir Kumar-Singh   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Recombinant Amyloid-β Peptide Aβ1–42 Aggregates Faster and Is More Neurotoxic than Synthetic Aβ1–42

(2009) Verena H. Finder et al.   JOURNAL OF MOLECULAR BIOLOGY

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

(2009) Jennifer L. Tomic et al.   NEUROBIOLOGY OF DISEASE

Amyloid-β E22Δ variant induces synaptic alteration in mouse hippocampal slices

(2009) Hiroshi Takuma et al.   NEUROREPORT

A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis

(2009) G. Di Fede et al.   SCIENCE

A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia

(2008) Takami Tomiyama et al.   ANNALS OF NEUROLOGY

Parenchymal and vascular Aβ-deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease

(2008) Dietmar Rudolf Thal et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE