Roles of ERK1/2 and PI3K/AKT signaling pathways in mitochondria-mediated apoptosis in testes of hypothyroid rats

Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways

(2016) JIMING LIU et al.   ONCOLOGY REPORTS

Crosstalk Between MAPK/ERK and PI3K/AKT Signal Pathways During Brain Ischemia/Reperfusion

(2015) Jing Zhou et al.   ASN Neuro

Gene expression profiling of the hippocampal dentate gyrus in an adult toxicity study captures a variety of neurodevelopmental dysfunctions in rat models of hypothyroidism

(2015) Ayako Shiraki et al.   JOURNAL OF APPLIED TOXICOLOGY

Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling

(2015) Pei-Li Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of hypothyroidism on oxidative stress, c-Fos expression, cell cycle, and apoptosis in rats testes

(2015) Jun-Ling Wang et al.   TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY

Enhanced proliferation of bone marrow mesenchymal stem cells by co-culture with TM4 mouse Sertoli cells: involvement of the EGF/PI3K/AKT pathway

(2014) Huan Tian et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mitochondrial estrogen receptor β inhibits cell apoptosis via interaction with Bad in a ligand-independent manner

(2014) Jiayi Liang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Overexpression of DDX43 Mediates MEK Inhibitor Resistance through RAS Upregulation in Uveal Melanoma Cells

(2014) G. Ambrosini et al.   MOLECULAR CANCER THERAPEUTICS

Osthole Exhibits Anti-Cancer Property in Rat Glioma Cells Through Inhibiting PI3K/Akt and MAPK Signaling Pathways

(2013) Daofang Ding et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Carboxypeptidase E/NFα1: A New Neurotrophic Factor against Oxidative Stress-Induced Apoptotic Cell Death Mediated by ERK and PI3-K/AKT Pathways

(2013) Yong Cheng et al.   PLoS One

PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1

(2013) H. Ebi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2,3,7,8-Tetrachlorodibenzo-p-dioxin stimulates proliferation of HAPI microglia by affecting the Akt/GSK-3β/cyclin D1 signaling pathway

(2013) Guangfei Xu et al.   TOXICOLOGY LETTERS

Oxidant Stress and Mitochondrial Signaling Regulate Reversible Changes of ERα Expression and Apoptosis in Aging Mouse Glomeruli and Mesangial Cells

(2012) Simone Pereira-Simon et al.   ENDOCRINOLOGY

The G Protein–Coupled Receptor GPR30 Mediates the Nontranscriptional Effect of Estrogen on the Activation of PI3K/Akt Pathway in Endometrial Cancer Cells

(2012) Xin Ge et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Estrogen receptor β stimulates Egr-1 transcription via MEK1/Erk/Elk-1 cascade in C6 glioma cells

(2011) Ji-Ha Kim et al.   BMB Reports

Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer

(2011) E E Vincent et al.   BRITISH JOURNAL OF CANCER

Estrogen signaling in testicular cells

(2011) S. Carreau et al.   LIFE SCIENCES

Disruption of spermatogenesis and differential regulation of testicular estrogen receptor expression in mice after polychlorinated biphenyl exposure

(2011) Jiali Cai et al.   TOXICOLOGY

Estrogen receptors and function in the male reproductive system

(2010) Maria Fatima Magalhães Lazari et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Expression and Signaling of G Protein-Coupled Estrogen Receptor 1 (GPER) in Rat Sertoli Cells1

(2010) Thaís F. G. Lucas et al.   BIOLOGY OF REPRODUCTION

Thyroid Function and Human Reproductive Health

(2010) G. E. Krassas et al.   ENDOCRINE REVIEWS

T3 fails to restore mitochondrial thiol redox status altered by experimental hypothyroidism in rat testis

(2010) Sutapa Chattopadhyay et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Direct antioxidant and protective effect of estradiol on isolated mitochondria

(2009) Consuelo Borrás et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Novel Estrogen Receptor, G Protein-Coupled Receptor 30, Mediates the Proliferative Effects Induced by 17β-Estradiol on Mouse Spermatogonial GC-1 Cell Line

(2008) Rosa Sirianni et al.   ENDOCRINOLOGY

Steroid and thyroid hormone receptors in mitochondria

(2008) Anna-Maria G. Psarra et al.   IUBMB LIFE

Propylthiouracil-induced congenital hypothyroidism upregulates vimentin phosphorylation and depletes antioxidant defenses in immature rat testis

(2008) Ariane Zamoner et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Estradiol facilitates neurite maintenance by a Src/Ras/ERK signalling pathway

(2008) Alfredo Miñano et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain

(2008) Ariane Zamoner et al.   NEUROTOXICOLOGY

The proliferative effect of estradiol on human prostate stromal cells is mediated through activation of ERK

(2008) Zhisong Zhang et al.   PROSTATE

Hypothyroidism impairs antioxidant defence system and testicular physiology during development and maturation

(2007) Dipak K. Sahoo et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY