Article
Pharmacology & Pharmacy
Qiyuan Shan, Gang Tian, Xin Han, Hui Hui, Mai Yamamoto, Min Hao, Jingwei Wang, Kuilong Wang, Xianan Sang, Luping Qin, Guanqun Chen, Gang Cao
Summary: This study conducted subacute toxicity and metabolomics research on Tetradium ruticarpum (TR). The results showed that rats did not show obvious subacute toxicity when receiving three times the recommended dose of TR, but high doses caused liver damage. Processing could effectively reduce the toxicity of TR, and metabolomics analysis revealed the toxicity metabolic regulatory network. The study is important for understanding the toxicity mechanisms of TR, supporting traditional processing theory, and guiding clinical use.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Environmental Sciences
M. Solis, N. Cappelletti, C. Bonetto, M. Franco, S. Fanelli, J. Amalvy, H. Mugni
Summary: This study found that riparian wetlands can mitigate pesticide pollution, playing an important role in protecting the aquatic ecosystem.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biotechnology & Applied Microbiology
Farhad Shafiei, Mathew P. Watts, Lukas Pajank, John W. Moreau
Summary: This study experimentally tested the tolerance of an autotrophic SCN--degrading bacterial consortium enriched from gold mine tailings for Zn, Cu, Ni, Cr, and As. The results showed that all selected metals inhibited SCN- biodegradation to different extents depending on concentration, highlighting the importance of considering metal co-contamination in bioreactor design for SCN- bioremediation at mine sites.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Environmental Sciences
Yi-Cheng Xu, Nan Li, Xiufeng Yan, Hui-Xi Zou
Summary: In this study, the interaction between metal ions and four types of siderophore was modeled and analyzed. The results showed that the siderophores exhibited different levels of selectivity towards various metal ions, which was determined by the electronegativity and ionic radius of the siderophore functional groups and metals, as well as the interaction between them. Moreover, cyclic siderophores were found to be more stable than linear ones for metal binding.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Shaked Uzi-Gavrilov, Zohar Tik, Omer Sabti, Michael M. Meijler
Summary: Chemical communication between P. aeruginosa and S. aureus in biofilms of cystic fibrosis patients was found to promote cooperation, leading to increased disease severity and antibiotic resistance. Through metabolomics analysis and synthetic validation, it was discovered that S. aureus can convert pyochelin into a compound with reduced affinity for iron, allowing it to coexist more readily with P. aeruginosa and forming robust dual-species biofilms.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Marine & Freshwater Biology
Yanina L. Idaszkin, Rosana Polifroni, Jennifer Mesa-Marin
Summary: This study isolated various bacteria with plant growth promoting attributes in the Patagonian salt marshes, primarily from the rhizosphere of halophytes in heavy metal polluted areas of San Antonio salt marsh. The results indicated that bacteria in polluted soils were more likely to possess plant growth promoting properties, suggesting that coastal hazardous scenarios may be a good opportunity to seek for PGPR.
ESTUARINE COASTAL AND SHELF SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Arsha Antony, Tiju Thomas, Cyril Augustine
Summary: Iron is an essential metal for living organisms, but its distribution in tissues is constrained. Insolubility of Fe(III) ions in aqueous systems reduces direct uptake by cells, while free-Fe entities can lead to cell destruction. Therefore, a protective coordination environment is necessary for Fe acquisition, transport, storage, and utilization in tissues. Siderophores are polydentate ligands used by bacterial cells to acquire Fe(III) ions with a high affinity. This research focuses on the coordination chemistry of the siderophore cepabactin (Cep), confirming that the Fe-III(Cep)(3) complex is octahedral and high spin, with Cep's oxygen atoms acting as electron donors.
JOURNAL OF MOLECULAR MODELING
(2023)
Review
Agronomy
Soundarya Rajapitamahuni, Bo Ram Kang, Tae Kwon Lee
Summary: Arbuscular mycorrhizal fungi form a vital symbiotic relationship with plants to enhance plant-iron homeostasis and improve nutrient uptake. This symbiosis facilitates iron solubility by altering root architecture and producing iron-binding root exudates. Additionally, interactions with soil bacteria, including siderophore-producing bacteria, further enhance the benefits of mycorrhizal symbiosis. However, molecular mechanisms involved in these intricate networks are still largely unknown.
Review
Environmental Sciences
Gema Rodriguez-Moro, Sara Ramirez-Acosta, Belen Callejon-Leblic, Ana Arias-Borrego, Tamara Garcia-Barrera, Jose-Luis Gomez-Ariza
Summary: The increasing interest in the environment, climate change, and quality of life has led to new methodological proposals, particularly in the field of omics methodology, which represents a milestone in environmental studies. The study of toxic metals is of special interest, with new instrumental platforms and methodological approaches being developed to address these issues.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Microbiology
Habtamu Asrat, Jevon Samaroo-Campbell, Subhan Ata, John Quale
Summary: The development of resistance to cefiderocol among multidrug resistant Acinetobacter baumannii has been attributed to downregulation in iron transport systems and a variety of beta-lactamases. However, the precise contribution of each in clinical isolates remains to be determined. This study investigated 16 clinical isolates with varying degrees of cefiderocol resistance, analyzing the expression of iron transport systems and beta-lactamases, as well as determining the impact of silencing the bla(ADC) gene and the addition of avibactam. The results showed that resistance to cefiderocol in Acinetobacter baumannii is associated with over-expression of specific bla(ADC) subtypes, along with repression of ferric uptake systems.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2023)
Article
Biochemistry & Molecular Biology
Wojciech Swiatkowski, Barbara Budzynska, Monika Maciag, Agnieszka Swiatkowska, Przemko Tylzanowski, Mansur Rahnama-Hezavah, Piotr Stachurski, Renata Chalas
Summary: Tobacco smoking poses a serious health problem, as even small doses of nicotine can have potentially lethal effects on adults. The administration method of nicotine also affects its toxicity. Cytisine, a popular medication for nicotine addiction treatment, was evaluated in this study for its effects on nicotine-induced embryotoxicity using zebrafish larvae. Nicotine increased mortality and delayed hatching of zebrafish larvae, while cytisine did not affect mortality and only caused hatching delay at high concentrations. The combination of the two compounds partially reduced the adverse teratogenic effect of nicotine. This study provides insights for future research or treatments related to nicotine addiction or prenatal nicotine exposure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Fei Han, Jihao Li, Wenrui Wang, Mouhua Wang, Linfan Li
Summary: In this study, a simple and fast synthesis method for silver nanoclusters (AgNCs) was developed. The synthesized AgNCs exhibited fluorescence properties, which could be controlled by various factors. The fluorescence emission of the AgNCs depended on the excitation wavelength. Furthermore, the AgNCs were used as fluorescent probes for the detection of Cr3+ ions.
Article
Chemistry, Multidisciplinary
Giancarla Alberti, Camilla Zanoni, Vittorio Losi, Sara Rovertoni, Lisa Rita Magnaghi, Osian Fonquernie, Stephane Brandes, Agnese Amati, Jean-Claude Chambron, Nicolas Maudoux, Raffaela Biesuz, Michel Meyer
Summary: This study presents a new solid-phase sorbent, DFO@Purolite, obtained by functionalizing a commercial epoxy methacrylate resin with desferrioxamine B (DFO), for the sorption of iron(III) and zirconium(IV). The sorption properties were investigated in detail, including kinetics, isotherms, and pH dependence. The stoichiometry and complexation constants were determined using the Gibbs-Donnan model, revealing good agreement with previous studies in homogeneous solutions and providing insights into a controversial speciation model.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Environmental Sciences
Marta Marcinczyk, Patrycja Krasucka, Aleksandra Bogusz, Beata Tomczyk, Wenyan Duan, Bo Pan, Patryk Oleszczuk
Summary: This study aims to evaluate the ecotoxicological effects of different methods of zinc-modified biochar (BC-Zn). Invertebrates (Folsomia candida, Daphnia magna) and bacteria (Aliivibrio fischeri) were used to assess the toxicity of different BC-Zn treatments. The post-treated and calcined composites had higher levels of total polycyclic aromatic hydrocarbons (C-tot PAHs) compared to the pre-modified BC-Zn, but they had limited impact on the luminescence activity of bacteria.
Article
Biochemistry & Molecular Biology
Muriel Viau, Laurene Sonzogni, Melanie L. Ferlazzo, Elise Berthel, Sandrine Pereira, Larry Bodgi, Adeline Granzotto, Clement Devic, Beatrice Fervers, Laurent Charlet, Nicolas Foray
Summary: Studies suggest that metals may induce DSB through the nucleo-shuttling of ATM, affecting toxicity and carcinogenicity. The properties, concentration, and tissue type of different metals can all have an impact on this process.
