In vitro anti-inflammatory and antimicrobial potential of leaf extract from Artemisia nilagirica (Clarke) Pamp

In the present investigation, the bioactive compounds from the leaf extract of Artemisia nilagirica showed potent anti-inflammatory and antimicrobial activity. The leaf extract showed a maximum protection of human red blood cells (HRBC) with 74.63% at 20 mu g/mL concentration, and the minimum hemolysis was 25.37% in a hypotonic solution with diclofenac as the control. The in vitro antimicrobial activity of plant extract against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhi, Proteus vulgaris, Yersinia enterocolitica, Bacillus subtilis, and Candida albicans was evaluated at various concentrations (50, 100, 150, and 200 mu g). The maximum zone of inhibition was observed against P. aeruginosa followed by B. subtilis, S. typhi, S. aureus and E. coli. The leaf extract also showed potent activity against C. albicans. (C) 2018 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.