PML body meets telomere

Expression of Telomeres in Astrocytoma WHO Grade 2 to 4: TERRA Level Correlates with Telomere Length, Telomerase Activity, and Advanced Clinical Grade

(2014) Sandra Sampl et al.   Translational Oncology

Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer

(2012) Jian Hu et al.   CELL

A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics

(2012) Ellen Van Damme et al.   International Journal of Biological Sciences

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Telomerase-Independent Paths to Immortality in Predictable Cancer Subtypes

(2012) Stephen T Durant   Journal of Cancer

Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes

(2011) Christopher M. Heaphy et al.   AMERICAN JOURNAL OF PATHOLOGY

A three-dimensional colocalization RNA interference screening platform to elucidate the alternative lengthening of telomeres pathway

(2011) Sarah Osterwald et al.   Biotechnology Journal

Nuclear organization in genome stability: SUMO connections

(2011) Shigeki Nagai et al.   CELL RESEARCH

Normal mammalian cells negatively regulate telomere length by telomere trimming

(2011) H. A. Pickett et al.   HUMAN MOLECULAR GENETICS

De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation

(2011) I. Chung et al.   JOURNAL OF CELL SCIENCE

The alternative lengthening of telomeres pathway may operate in non-neoplastic human cells

(2011) Tania L Slatter et al.   JOURNAL OF PATHOLOGY

HP1-Mediated Formation of Alternative Lengthening of Telomeres-Associated PML Bodies Requires HIRA but Not ASF1a

(2011) Wei-Qin Jiang et al.   PLoS One

Altered Telomeres in Tumors with ATRX and DAXX Mutations

(2011) C. M. Heaphy et al.   SCIENCE

Pilocytic Astrocytomas Have Telomere-Associated Promyelocytic Leukemia Bodies without Alternatively Lengthened Telomeres

(2010) Tania Slatter et al.   AMERICAN JOURNAL OF PATHOLOGY

Prognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis

(2010) Lorenza Venturini et al.   BMC CANCER

The Telomerase Inhibitor Imetelstat Depletes Cancer Stem Cells in Breast and Pancreatic Cancer Cell Lines

(2010) I. Joseph et al.   CANCER RESEARCH

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner

(2010) Martin J. Law et al.   CELL

Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers

(2010) Jeremy D. Henson et al.   FEBS LETTERS

Alternative lengthening of telomeres pathway: Recombination-mediated telomere maintenance mechanism in human cells

(2010) A. Nabetani et al.   JOURNAL OF BIOCHEMISTRY

Three-dimensional organization of promyelocytic leukemia nuclear bodies

(2010) M. Lang et al.   JOURNAL OF CELL SCIENCE

SUMOylation-Dependent Localization of IKKɛ in PML Nuclear Bodies Is Essential for Protection against DNA-Damage-Triggered Cell Death

(2010) Florian Renner et al.   MOLECULAR CELL

Alternative lengthening of telomeres: models, mechanisms and implications

(2010) Anthony J. Cesare et al.   NATURE REVIEWS GENETICS

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PML Nuclear Bodies

(2010) V. Lallemand-Breitenbach et al.   Cold Spring Harbor Perspectives in Biology

Telomere length maintenance – an ALTernative mechanism

(2009) N.J. Royle et al.   CYTOGENETIC AND GENOME RESEARCH

Control of telomere length by a trimming mechanism that involves generation of t-circles

(2009) Hilda A Pickett et al.   EMBO JOURNAL

Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins

(2009) Wei-Qin Jiang et al.   JOURNAL OF CELL BIOLOGY

Telomere biology in neuroblastoma: telomere binding proteins and alternative strengthening of telomeres

(2009) Yoshiyuki Onitake et al.   JOURNAL OF PEDIATRIC SURGERY

Dynamics of Telomeres and Promyelocytic Leukemia Nuclear Bodies in a Telomerase-negative Human Cell Line

(2009) Thibaud Jegou et al.   MOLECULAR BIOLOGY OF THE CELL

Telomeric DNA Mediates De Novo PML Body Formation

(2009) Anneke K. Brouwer et al.   MOLECULAR BIOLOGY OF THE CELL

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity

(2009) Jeremy D Henson et al.   NATURE BIOTECHNOLOGY

Telomere recombination requires the MUS81 endonuclease

(2009) Sicong Zeng et al.   NATURE CELL BIOLOGY

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions

(2009) Anthony J Cesare et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription

(2009) Laura J. Ng et al.   NUCLEIC ACIDS RESEARCH

Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination

(2009) I. Draskovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Genome organization: Balancing stability and plasticity

(2008) Malte Wachsmuth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma

(2008) C J Cairney et al.   BRITISH JOURNAL OF CANCER

Telomere elongation involves intra-molecular DNA replication in cells utilizing alternative lengthening of telomeres

(2008) A. Muntoni et al.   HUMAN MOLECULAR GENETICS

Dynamics of component exchange at PML nuclear bodies

(2008) S. Weidtkamp-Peters et al.   JOURNAL OF CELL SCIENCE

Live Cell Dynamics of Promyelocytic Leukemia Nuclear Bodies upon Entry into and Exit from Mitosis

(2008) Yi-Chun M. Chen et al.   MOLECULAR BIOLOGY OF THE CELL

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

(2008) Nadya Dimitrova et al.   NATURE

New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163

(2008) Rintaro Hashizume et al.   NEURO-ONCOLOGY

Telomere uncapping and alternative lengthening of telomeres

(2007) Anthony J. Cesare et al.   MECHANISMS OF AGEING AND DEVELOPMENT