Shelterin complex and associated factors at human telomeres

The telomere protein tankyrase 1 regulates DNA damage responses at telomeres

(2016) Sandy Chang   Aging-US

LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection

(2016) Samantha A. Sheppard et al.   Aging-US

Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs

(2016) Ryan C. Dregalla et al.   Aging-US

MCPH1 patient cells exhibit delayed release from DNA damage-induced G2/M checkpoint arrest 

(2011) Ioannis Gavvovidis et al.   CELL CYCLE

TRF2 and Apollo Cooperate with Topoisomerase 2α to Protect Human Telomeres from Replicative Damage

(2010) Jing Ye et al.   CELL

Evolution of CST function in telomere maintenance

(2010) Carolyn Price et al.   CELL CYCLE

SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair

(2010) Yung C Lam et al.   EMBO JOURNAL

The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response

(2010) Helga B Landsverk et al.   EMBO REPORTS

Multiple roles of ATM in monitoring and maintaining DNA integrity

(2010) Frederick A. Derheimer et al.   FEBS LETTERS

TERRA biogenesis, turnover and implications for function

(2010) Sascha Feuerhahn et al.   FEBS LETTERS

FEN1 Ensures Telomere Stability by Facilitating Replication Fork Re-initiation

(2010) Abhishek Saharia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomerase Inhibitor PinX1 Provides a Link between TRF1 and Telomerase to Prevent Telomere Elongation

(2010) Christina Y. Soohoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Revealing Novel Telomere Proteins Usingin VivoCross-linking, Tandem Affinity Purification, and Label-free Quantitative LC-FTICR-MS

(2010) Thalia Nittis et al.   MOLECULAR & CELLULAR PROTEOMICS

Genome-wide YFP Fluorescence Complementation Screen Identifies New Regulators for Telomere Signaling in Human Cells

(2010) Ok-Hee Lee et al.   MOLECULAR & CELLULAR PROTEOMICS

Apollo—Taking the Lead in Telomere Protection

(2010) Jay F. Sarthy et al.   MOLECULAR CELL

A Shld1-Controlled POT1a Provides Support for Repression of ATR Signaling at Telomeres through RPA Exclusion

(2010) Yi Gong et al.   MOLECULAR CELL

CST Meets Shelterin to Keep Telomeres in Check

(2010) Marie-Josèphe Giraud-Panis et al.   MOLECULAR CELL

Apollo Contributes to G Overhang Maintenance and Protects Leading-End Telomeres

(2010) Peng Wu et al.   MOLECULAR CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase

(2010) Sophie Redon et al.   NUCLEIC ACIDS RESEARCH

RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination

(2010) E.-J. Uringa et al.   NUCLEIC ACIDS RESEARCH

The Protein Network Surrounding the Human Telomere Repeat Binding Factors TRF1, TRF2, and POT1

(2010) Richard J. Giannone et al.   PLoS One

Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndrome

(2010) F. Touzot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling

(2010) Z. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of Rap1 Induces Telomere Recombination in the Absence of NHEJ or a DNA Damage Signal

(2010) A. Sfeir et al.   SCIENCE

Multiple Roles of BRIT1/MCPH1 in DNA Damage Response, DNA Repair, and Cancer Suppression

(2010) Shiaw-Yih Lin et al.   YONSEI MEDICAL JOURNAL

Dyskeratosis congenita, stem cells and telomeres

(2009) Michael Kirwan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Purification of Proteins Associated with Specific Genomic Loci

(2009) Jérôme Déjardin et al.   CELL

Telomere Extension Occurs at Most Chromosome Ends and Is Uncoupled from Fill-In in Human Cancer Cells

(2009) Yong Zhao et al.   CELL

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

The Shelterin Protein TRF2 Inhibits Chk2 Activity at Telomeres in the Absence of DNA Damage

(2009) Giacomo Buscemi et al.   CURRENT BIOLOGY

14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response

(2009) Duaa H. Mohammad et al.   DNA REPAIR

Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ

(2009) Susan J. Hsiao et al.   JOURNAL OF CELL BIOLOGY

GNL3L stabilizes the TRF1 complex and promotes mitotic transition

(2009) Qubo Zhu et al.   JOURNAL OF CELL BIOLOGY

Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells

(2009) Silvia Canudas et al.   JOURNAL OF CELL BIOLOGY

Telomeric armor: the layers of end protection

(2009) L. Oganesian et al.   JOURNAL OF CELL SCIENCE

The Mre11 Complex and the Response to Dysfunctional Telomeres

(2009) C. L. Attwooll et al.   MOLECULAR AND CELLULAR BIOLOGY

Cell Cycle-Dependent Role of MRN at Dysfunctional Telomeres: ATM Signaling-Dependent Induction of Nonhomologous End Joining (NHEJ) in G1 and Resection-Mediated Inhibition of NHEJ in G2

(2009) N. Dimitrova et al.   MOLECULAR AND CELLULAR BIOLOGY

Arginine Methylation Regulates Telomere Length and Stability

(2009) T. R. H. Mitchell et al.   MOLECULAR AND CELLULAR BIOLOGY

Telomere Protection by TPP1 Is Mediated by POT1a and POT1b

(2009) T. Kibe et al.   MOLECULAR AND CELLULAR BIOLOGY

RPA-like Mammalian Ctc1-Stn1-Ten1 Complex Binds to Single-Stranded DNA and Protects Telomeres Independently of the Pot1 Pathway

(2009) Yasuyuki Miyake et al.   MOLECULAR CELL

TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

(2009) Zhong Deng et al.   MOLECULAR CELL

Multiple roles for MRE11 at uncapped telomeres

(2009) Yibin Deng et al.   NATURE

TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs

(2009) Hyeung Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ku86 represses lethal telomere deletion events in human somatic cells

(2009) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CpG-island promoters drive transcription of human telomeres

(2009) S. G. Nergadze et al.   RNA

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Flap Endonuclease 1 Contributes to Telomere Stability

(2008) Abhishek Saharia et al.   CURRENT BIOLOGY

Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2

(2008) A. Konishi et al.   GENES & DEVELOPMENT

Engineered telomere degradation models dyskeratosis congenita

(2008) D. Hockemeyer et al.   GENES & DEVELOPMENT

How ATR turns on: TopBP1 goes on ATRIP with ATR

(2008) A. E. Burrows et al.   GENES & DEVELOPMENT

Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres

(2008) Yasutoshi Tatsumi et al.   GENES TO CELLS

Human XPF controls TRF2 and telomere length maintenance through distinctive mechanisms

(2008) Yili Wu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

WRN Controls Formation of Extrachromosomal Telomeric Circles and Is Required for TRF2 B-Mediated Telomere Shortening

(2008) B. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Telomeric RNA enters the game

(2008) Béatrice Horard et al.   NATURE CELL BIOLOGY

Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

(2008) Tae Ho Lee et al.   NATURE CELL BIOLOGY

Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase

(2008) Gregory Sowd et al.   NUCLEIC ACIDS RESEARCH

Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links

(2008) J-B Bae et al.   ONCOGENE

A Shared Docking Motif in TRF1 and TRF2 Used for Differential Recruitment of Telomeric Proteins

(2008) Y. Chen et al.   SCIENCE

Tankyrase function at telomeres, spindle poles, and beyond

(2007) Susan J. Hsiao et al.   BIOCHIMIE

Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities

(2004) Shingo Hanaoka et al.   PROTEIN SCIENCE