Addressing health disparities in Hispanic breast cancer: accurate and inexpensive sequencing of BRCA1 and BRCA2

New recurrent BRCA1/2 mutations in Polish patients with familial breast/ovarian cancer detected by next generation sequencing

(2015) Anna Kluska et al.   BMC Medical Genomics

Next-Generation Sequencing of the BRCA1 and BRCA2 Genes for the Genetic Diagnostics of Hereditary Breast and/or Ovarian Cancer

(2015) Daniel Trujillano et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Validation of an NGS Approach for Diagnostic BRCA1/BRCA2 Mutation Testing

(2015) Daniela Dacheva et al.   Molecular Diagnosis & Therapy

Nonoptical Massive Parallel DNA Sequencing ofBRCA1andBRCA2Genes in a Diagnostic Setting

(2015) José Luis Costa et al.   HUMAN MUTATION

Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genes

(2014) Zhen Yeo et al.   BMC GENOMICS

Population-based screening for breast and ovarian cancer risk due toBRCA1andBRCA2

(2014) Efrat Gabai-Kapara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Decades After BRCA: Setting Paradigms in Personalized Cancer Care and Prevention

(2014) F. J. Couch et al.   SCIENCE

Risk of having BRCA1 mutation in high-risk women with triple-negative breast cancer: a meta-analysis

(2013) NM Tun et al.   CLINICAL GENETICS

Streamlined ion torrent PGM-based diagnostics: BRCA1 and BRCA2 genes as a model

(2013) Julien Tarabeux et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The new sequencer on the block: comparison of Life Technology’s Proton sequencer to an Illumina HiSeq for whole-exome sequencing

(2013) Joseph F. Boland et al.   HUMAN GENETICS

A Clinically Validated Diagnostic Second-Generation Sequencing Assay for Detection of Hereditary BRCA1 and BRCA2 Mutations

(2013) Ian E. Bosdet et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial

(2013) Shahneen K Sandhu et al.   LANCET ONCOLOGY

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Prevalence and Type of BRCA Mutations in Hispanics Undergoing Genetic Cancer Risk Assessment in the Southwestern United States: A Report From the Clinical Cancer Genetics Community Research Network

(2012) Jeffrey N. Weitzel et al.   JOURNAL OF CLINICAL ONCOLOGY

Long-Range PCR and Next-Generation Sequencing of BRCA1 and BRCA2 in Breast Cancer

(2012) Hilmi Ozcelik et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Development of a Next-Generation Sequencing Method for BRCA Mutation Screening

(2012) Maurice Chan et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Identification of the prevalent BRCA1 and BRCA2 mutations in the female population of Puerto Rico

(2012) Julie Dutil et al.   Cancer Genetics

Triple-negative breast cancer in Hispanic patients

(2011) Fernando Lara-Medina et al.   CANCER

Risk of cancer other than breast or ovarian in individuals with BRCA1 and BRCA2 mutations

(2011) A. Moran et al.   Familial Cancer

Underutilization of BRCA1/2 testing to guide breast cancer treatment: Black and Hispanic women particularly at risk

(2011) Douglas E Levy et al.   GENETICS IN MEDICINE

Massive parallel amplicon sequencing of the breast cancer genes BRCA1 and BRCA2: opportunities, challenges, and limitations

(2011) Kim De Leeneer et al.   HUMAN MUTATION

Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

(2011) T. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Molecular Phylogeny of Living Primates

(2011) Polina Perelman et al.   PLoS Genetics

Prevalence of BRCA1 and BRCA2 Mutations in Women with Breast Carcinoma In Situ and Referred for Genetic Testing

(2010) M. J. Hall et al.   Cancer Prevention Research

Genetic diagnosis of familial breast cancer using clonal sequencing

(2010) Joanne E. Morgan et al.   HUMAN MUTATION

Poly(ADP)-Ribose Polymerase Inhibition: Frequent Durable Responses inBRCACarrier Ovarian Cancer Correlating With Platinum-Free Interval

(2010) Peter C. Fong et al.   JOURNAL OF CLINICAL ONCOLOGY

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

(2010) Andrew Tutt et al.   LANCET

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

(2010) M William Audeh et al.   LANCET

The prevalence of BRCA1 mutations among young women with triple-negative breast cancer

(2009) SR Young et al.   BMC CANCER

Influence of Race/Ethnicity on Genetic Counseling and Testing for Hereditary Breast and Ovarian Cancer

(2009) Andrea D. Forman et al.   Breast Journal

BRCA1andBRCA2mutations in women of different ethnicities undergoing testing for hereditary breast-ovarian cancer

(2009) Michael J. Hall et al.   CANCER

Performance of Prediction Models for BRCA Mutation Carriage in Three Racial/Ethnic Groups: Findings from the Northern California Breast Cancer Family Registry

(2009) A. W. Kurian et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Associations of High-Grade Prostate Cancer with BRCA1 and BRCA2 Founder Mutations

(2009) I. Agalliu et al.   CLINICAL CANCER RESEARCH

Variation in breast cancer subtypes with age and race/ethnicity

(2009) Carol A. Parise et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Hereditary ovarian carcinoma: Heterogeneity, molecular genetics, pathology, and management

(2009) Henry T. Lynch et al.   Molecular Oncology

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of PARP inhibitors in oncology

(2008) Jordi Rodon et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

(2008) S. Rottenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA