Journal
NANOSCALE RESEARCH LETTERS
Volume 8, Issue -, Pages -Publisher
SPRINGEROPEN
DOI: 10.1186/1556-276X-8-482
Keywords
Au nanoparticle; AFM; Quantum dots; Blinking
Funding
- National Science Council of Taiwan [102-2627-M-007-002, 99-2120-M-007-009, 98-2120-M-007-001, 98-2627-M-007-002, 98-2627-M-007-001]
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This paper presents a novel method for the attachment of a 1.8-nm Au nanoparticle (Au-NP) to the tip of an atomic force microscopy (AFM) probe through the application of a current-limited bias voltage. The resulting probe is capable of picking up individual objects at the sub-4-nm scale. We also discuss the mechanisms involved in the attachment of the Au-NP to the very apex of an AFM probe tip. The Au-NP-modified AFM tips were used to pick up individual 4-nm quantum dots (QDs) using a chemically functionalized method. Single QD blinking was reduced considerably on the Au-NP-modified AFM tip. The resulting AFM tips present an excellent platform for the manipulation of single protein molecules in the study of single protein-protein interactions.
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