Article
Clinical Neurology
Qianqian Huang, Dinghong Lin, Shishi Huang, Yungang Cao, Yun Jin, Bo Wu, Linyu Fan, Wenzhan Tu, Lejian Huang, Songhe Jiang
Summary: This study investigated the global and local topological properties of the brain functional connectome in stroke patients and their associations with clinical measurements. The study found that the brain functional topologies in stroke patients were altered, although not significantly associated with upper extremity recovery. However, significant associations were observed between local degree in the right lateral occipital cortex and motor performance and recovery in right-sided stroke patients.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
David J. Lin, Kimberly S. Erler, Samuel B. Snider, Anna K. Bonkhoff, Julie A. DiCarlo, Nicole Lam, Jessica Ranford, Kristin Parlman, Audrey Cohen, Jennifer Freeburn, Seth P. Finklestein, Lee H. Schwamm, Leigh R. Hochberg, Steven C. Cramer
Summary: The study found that cognitive demands influenced upper extremity motor performance during recovery from acute stroke, with patients performing significantly worse on tasks with higher cognitive demands. Motor performance was related to cognitive dysfunction, especially in tasks involving cognitive demands, and neuroanatomic injury was associated with both the type of task and the location of the injury.
Article
Multidisciplinary Sciences
Guillermo Mendez-Rebolledo, Amanda L. Ager, Diana Ledezma, Julieta Montanez, Juan Guerrero-Henriquez, Carlos Cruz-Montecinos
Summary: This study aimed to investigate the association between active joint position sense (AJPS) of the shoulder complex and the performance of college volleyball players in functional tests. The results showed that AJPS at 90 degrees of internal rotation at 90 degrees of abduction was associated with performance in the Y-Balance Test-Upper Quarter and Seated Medicine Ball Throw.
Article
Engineering, Biomedical
Andrea M. Kuczynski, Adam Kirton, Jennifer A. Semrau, Sean P. Dukelow
Summary: This study explored the relationship between position sense and reaching ability in children with hemiparetic upper limbs following perinatal stroke using robotic technology and clinical measures. The findings suggest that deficits in sensory and motor function measured by robots are only moderately correlated with clinical tests, indicating relative independence between position sense and reaching with the contralesional limb in children with stroke.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Article
Clinical Neurology
J. Lee, H. Kim, J. Kim, H. -J. Lee, W. H. Chang, Y. -H. Kim
Summary: Our study found that predictive factors for upper extremity (UE) and lower extremity (LE) motor recovery post-stroke differ. Recovery of UE motor function is associated with age, NIHSS, MMSE, CST lesion load, lesion volume, ipsilesional CST integrity and interhemispheric homotopic functional connectivity, while LE motor recovery is related to ipsilesional and contralesional CST integrity and MMSE. Importantly, LE recovery is more closely linked to the preservation of cognitive function compared to UE.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Clinical Neurology
Nefeli Valyraki, Adrien Goujon, Marjorie Mateos, Adrien Lecoeuvre, Augustin Lecler, Igor Raynouard, Candice Sabben, Michael Obadia, Julien Savatovsky, Pierre Seners
Summary: The presence of MRI spot sign in patients with acute intracerebral hemorrhage is independently associated with hematoma expansion and poor functional outcome. The number of spot signs shows a dose-dependent effect on hematoma expansion and poor functional outcome.
JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Ying Song, ZhiFang Sun, WeiZhen Sun, MeiLing Luo, YiJun Du, Jing Jing, YongHui Wang
Summary: This study investigated the changes in resting-state functional connectivity (rsFC) in the sensorimotor cortex after strokes with left or right hemiplegia, considering lateralization and neuroplasticity. The results showed that the asymmetry of rsFC between the motor components in the left and right hemisphere disappeared in stroke groups. Additionally, the right hemiplegia group exhibited stronger rsFC between the left S1 and left M1, which correlated with motor function. The study also found a negative correlation between rsFC within the ipsi-lesioned M1 and motor function of the affected limb. The research has implications for brain-computer interfaces and transcranial magnetic regulation for cortical plasticity.
Article
Mathematical & Computational Biology
Hongming Liu, Yunyuan Gao, Wei Huang, Rihui Li, Michael Houston, Julia S. Benoit, Jinsook Roh, Yingchun Zhang
Summary: This study examines the alterations in inter-muscular coherence among upper extremity muscles in stroke patients. The results demonstrate higher coherence in synergistic muscle pairs in both control and stroke groups, with certain muscles showing weaker or stronger coherence in stroke patients in specific frequency ranges.
MATHEMATICAL BIOSCIENCES AND ENGINEERING
(2022)
Article
Orthopedics
Hui Xie, Gongcheng Xu, Congcong Huo, Wenhao Li, Haihong Zhao, Zeping Lv, Zengyong Li
Summary: The study found that in patients with ischemic stroke, there was a significant increase in wavelet amplitude values in the motor cortex under ISPC conditions, while there was no significant difference in hemorrhagic stroke patients. Additionally, ISPC may have a positive impact on the laterality index of the prefrontal cortex and motor cortex.
Article
Physiology
Shashwati Geed, Megan L. Grainger, Abigail Mitchell, Cassidy C. Anderson, Henrike L. Schmaulfuss, Seraphina A. Culp, Eilis R. McCormick, Maureen R. McGarry, Mystee N. Delgado, Allysa D. Noccioli, Julia Shelepov, Alexander W. Dromerick, Peter S. Lum
Summary: This study investigates the validity of using machine learning to measure real-world functional upper extremity use in stroke patients. The study hypothesizes that machine learning classification using wrist-worn accelerometry is as accurate as frame-by-frame video labeling. The study also validates the machine learning classification against measures of impairment, function, dexterity, and self-reported use. The results show that machine learning is a valid method for measuring functional upper extremity use.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Chemistry, Analytical
Pawel Sip, Marta Kozlowska, Dariusz Czysz, Przemyslaw Daroszewski, Przemyslaw Lisinski
Summary: Stroke is a major cause of disability, including loss of hand manipulative skills. Virtual reality (VR) is increasingly being used as a physiotherapeutic method. This study compared the effectiveness of VR application Virtual Mirror Hand 1.0 to classical mirror therapy in restoring post-stroke hand function. The results showed that VR application had subjective advantages in ameliorating pain and sensory impressions.
Article
Clinical Neurology
Youxin Sui, Chaojie Kan, Shizhe Zhu, Tianjiao Zhang, Jin Wang, Sheng Xu, Ren Zhuang, Ying Shen, Tong Wang, Chuan Guo
Summary: This study used functional near-infrared spectroscopy (fNIRS) to investigate the upper extremity motor impairment in subacute stroke patients and found that different degrees of upper extremity impairment were associated with functional connectivity between different brain regions. The connection between the ipsilesional dorsolateral prefrontal cortex (DLPFC) and bilateral primary motor cortex (M1) may play an important role in motor-related plasticity.
FRONTIERS IN NEUROLOGY
(2022)
Article
Rehabilitation
Adam de Havenon, Laura Heitsch, Abimbola Sunmonu, Robynne Braun, Keith R. Lohse, John W. Cole, Eva Mistry, Arne Lindgren, Bradford B. Worrall, Steven C. Cramer
Summary: The study aimed to develop a simple and effective risk score for predicting persistent impairment of upper extremity motor function in stroke patients at 90 days poststroke. By analyzing data from multiple clinical trials, the researchers identified the PUPPI index as a predictive tool in the validation cohort.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Rehabilitation
Shashwati Geed, Christianne J. Lane, Monica A. Nelsen, Steven L. Wolf, Carolee J. Winstein, Alexander W. Dromerick
Summary: The study found that in stroke rehabilitation trials, using a Rasch-rescaled UEFM can improve the accuracy of effect size, reduce the required sample size, decrease costs, shorten duration, and decrease the number of subjects exposed to experimental risks compared to using the simple summation of ordinal UEFM items.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Clinical Neurology
Hong Pan, Shamay S. M. Ng, Tai Wa Liu, Joshua Tsoh, Thomson W. L. Wong
Summary: This study aimed to culturally adapt and examine the psychometric properties of the Chinese (Cantonese) version of the Upper Extremity Functional Index (C-UEFI) in people with chronic stroke. The results showed that the C-UEFI demonstrated good test-retest reliability and excellent internal consistency. It is reliable and valid for assessing functional recovery of upper extremity activity in Chinese people with chronic stroke.
FRONTIERS IN NEUROLOGY
(2023)