5′ tRNA Halves: The Next Generation of Immune Signaling Molecules

Deep sequencing identifies circulating mouse miRNAs that are functionally implicated in manifestations of aging and responsive to calorie restriction

(2016) Joseph M Dhahbi et al.   Aging-US

Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C

(2015) Sara R. Selitsky et al.   Scientific Reports

tRNA fragments in human health and disease

(2014) Paul Anderson et al.   FEBS LETTERS

Angiogenin-Cleaved tRNA Halves Interact with Cytochrome c, Protecting Cells from Apoptosis during Osmotic Stress

(2014) M. Saikia et al.   MOLECULAR AND CELLULAR BIOLOGY

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

(2014) L. Vojtech et al.   NUCLEIC ACIDS RESEARCH

Identification and characterization of an ancient class of small RNAs enriched in serum associating with active infection

(2014) Yunfang Zhang et al.   Journal of Molecular Cell Biology

Gene Expression Changes Induced byTrypanosoma cruziShed Microvesicles in Mammalian Host Cells: Relevance of tRNA-Derived Halves

(2014) Maria R. Garcia-Silva et al.   Biomed Research International

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

(2013) Joseph M Dhahbi et al.   BMC GENOMICS

Beyond microRNA – Novel RNAs derived from small non-coding RNA and their implication in cancer

(2013) Elena S. Martens-Uzunova et al.   CANCER LETTERS

5′-YRNA fragments derived by processing of transcripts from specific YRNA genes and pseudogenes are abundant in human serum and plasma

(2013) Joseph M. Dhahbi et al.   PHYSIOLOGICAL GENOMICS

Identification of stable, high copy number, medium-sized RNA degradation intermediates that accumulate in plants under non-stress conditions

(2013) Martyna Nowacka et al.   PLANT MOLECULAR BIOLOGY

Extracellular small RNAs: what, where, why?: Figure 1

(2012) Anna M. Hoy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A novel class of tRNA-derived small RNAs extremely enriched in mature mouse sperm

(2012) Hongying Peng et al.   CELL RESEARCH

Genome-wide Identification and Quantitative Analysis of Cleaved tRNA Fragments Induced by Cellular Stress

(2012) Mridusmita Saikia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 2′-O-methylation status of a single guanosine controls transfer RNA–mediated Toll-like receptor 7 activation or inhibition

(2012) Stefanie Jöckel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification and Functional Characterization of tRNA-derived RNA Fragments (tRFs) in Respiratory Syncytial Virus Infection

(2012) Qingrong Wang et al.   MOLECULAR THERAPY

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

(2012) Esther N. M. Nolte-’t Hoen et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small RNAs derived from longer non-coding RNAs

(2011) Susanne Röther et al.   BIOCHIMIE

Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation

(2011) Pavel Ivanov et al.   MOLECULAR CELL

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

MicroRNAs in body fluids—the mix of hormones and biomarkers

(2011) Maria Angelica Cortez et al.   Nature Reviews Clinical Oncology

Transfer RNA-derived fragments: origins, processing, and functions

(2011) Andrew Sobala et al.   Wiley Interdisciplinary Reviews-RNA

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly

(2010) Mohamed M. Emara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A population of tRNA-derived small RNAs is actively produced in Trypanosoma cruzi and recruited to specific cytoplasmic granules

(2010) Maria Rosa Garcia-Silva et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

Discovery of microRNAs and other small RNAs in solid tumors

(2010) Eti Meiri et al.   NUCLEIC ACIDS RESEARCH

Capture and sequence analysis of RNAs with terminal 2',3'-cyclic phosphates

(2010) K. Schutz et al.   RNA

Stressing Out over tRNA Cleavage

(2009) Debrah M. Thompson et al.   CELL

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)

(2009) Yong Sun Lee et al.   GENES & DEVELOPMENT

The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress inSaccharomyces cerevisiae

(2009) Debrah M. Thompson et al.   JOURNAL OF CELL BIOLOGY

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

The Phloem-Delivered RNA Pool Contains Small Noncoding RNAs and Interferes with Translation

(2009) S. Zhang et al.   PLANT PHYSIOLOGY

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

(2009) A. Zernecke et al.   Science Signaling

Hidden layers of human small RNAs

(2008) Hideya Kawaji et al.   BMC GENOMICS

Stress induces tRNA cleavage by angiogenin in mammalian cells

(2008) Hanjiang Fu et al.   FEBS LETTERS

Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis

(2008) Christoph Jöchl et al.   NUCLEIC ACIDS RESEARCH

tRNA cleavage is a conserved response to oxidative stress in eukaryotes

(2008) D. M. Thompson et al.   RNA